Method of Testing for Endometriosis and Treatment Therefor

ABSTRACT

The present invention relates to novel genetic markers associated with endometriosis and risk of developing endometriosis, and methods and materials for determining whether a human subject has endometriosis or is at risk of developing endometriosis and the use of such risk information in selectively administering a treatment that at least partially prevents or compensates for an endometriosis related symptom.

CROSS REFERENCE TO RELATED APPLICATIONS

This nonprovisional utility patent application is a continuation of and claims the benefit under 35 USC §120 to co-pending U.S. application Ser. No. 13/789,082 filed Mar. 7, 2013 and scheduled to issue Sep. 6, 2016 as U.S. Pat. No. 9,434,991 and which is incorporated herein in its entirety by this reference.

FIELD OF THE INVENTION

The present invention relates to endometriosis prognosis, diagnosis and therapy. In particular, the present invention relates to a novel algorithmic combination of endometriosis associated single nucleotide polymorphisms (SNPs) and Rare Variants (RVs), and endometriosis related clinical analysis to result in an endometriosis predictive and/or diagnostic test and related treatment therefor.

BACKGROUND OF THE INVENTION

Endometriosis may include autoimmune endometriosis, mild endometriosis, moderate endometriosis, severe endometriosis, superficial (peritoneal) endometriosis, deep (invasive) endometriosis, ovarian endometriosis, endometriosis-related cancers, and “endometriosis-associated conditions”. For the purpose of this invention the term endometriosis is used to describe any of these conditions.

Endometriosis is most generally defined as the presence of endometrium (glands and stroma) at sites outside of the uterus (ectopic endometrial tissues rather than eutopic or within the uterus). The most common sites are the ovaries, pelvic peritoneum, uterosacral ligaments, pouch of Douglas, and rectovaginal septum although implants have been identified on the peritoneal surfaces of the abdomen (these may grow into the intestines, ureters or bladder), in the thorax, at the umbilicus, and at incision sites of prior surgeries (Child T J, Tan S L (2001) Endometriosis: aetiology, pathogenesis and treatment, Drugs 61:1735-1750; Giudice et al. (1998) Status of current research on endometriosis, The Journal of reproductive medicine 43:252-262).

Endometriosis is a common gynecologic disorder. The prevalence is difficult to know. It has been estimated that it affects approximately 14% of all women (range 1-43%), 40-60% of women with pelvic pain and 30%-50% of infertile women (Di Blasio et al. (2005) Genetics of endometriosis, Minerva ginecologica 57:225-236; Schindler AE (2004) Pathophysiology, diagnosis and treatment of endometriosis, Minerva ginecologica 56:419-435).

A non-surgical method of clinically assessing a predisposition to endometriosis is to determine the answer to three distinct endometriosis related questions, each question having an associated Odds Ratio (OR), as shown in FIG. 1. The results of answers to the FIG. 1 questions are then complied according to the endometriosis clinical factor assessment chart as shown in FIG. 2 resulting in a Raw Clinical Probability Value (RCPV). The RCPV is preferably multiplied by a Relevance Factor (RF) based on a patient's age and race to result in a Final Clinical Probability Value (FCPV). Alternatively, the RCPV may be used with data collected in population surveys.

MultiDimensional Analysis (MDA) is an analysis process that groups data into two or more categories (e.g. cases and controls or patients having a high probability of endometriosis and patients having a low probability of endometriosis).

Logistic regression analysis is a process that is used for prediction of the probability of occurrence of an event by fitting data to a logit function logistic curve.

Bayesian analysis or Bayesian interference is a method of statistical inference in which evidence is used to estimate parameters and predictions in a probability model.

It is known to treat or prevent endometriosis, especially in women who have no outwardly manifest symptoms of endometriosis, by the prophylactic administration of a therapeutic. The administered therapeutic may be any of a hormonal treatment such as an estrogen containing composition, a progesterone containing composition, a progestin containing composition, a gonadotropin releasing-hormone (GnRH) agonist, or other ovulation suppression composition, an advanced reproductive therapy or ART (ART is used to treat endometriosis related infertility and may include any fertility treatments in which the egg or sperm are “handled” in vitro as part of the treatment), or a combination thereof. In particular, the therapeutic may be administered in the form of an oral contraceptive (OC). The GnRH therapeutic may take the form of a GnRH agonist in combination with a patient specific substantially low dose of estrogen, progestin, or tibolone. Such administration of a low dose of estrogen, progestin, or tibolone in combination with a GnRH agonist to compensate potential side effects of the GnRH agonist are commonly referred to as an “add-back” therapy. It is noted that in such add-back therapy, the dosage of estrogen, progestin, or tibolone is relatively small so as to not reduce the effectiveness of the GnRH agonist.

Various genetic markers are known to have a predictive association with endometriosis. Such genetic markers and methods are disclosed for instance in U.S. patent application Ser. Nos. 12/056,754, 12/120,322, 12/566,933, 12/765,643, 13/159,132, 13/602,409, 13/603,284, 13/603,297, 13/652,018, 61/721,219, 61/717,048, and 61/717,053, all of which are incorporated herein in their entirety by this reference.

SUMMARY OF THE INVENTION

The present invention defines a method for endometriosis diagnosis/prognosis that preferably combines known endometriosis clinical factor assessment methods with endometriosis associated biomarkers such as single nucleotide polymorphisms (SNPs), indels, insertions, deletions, genomic rearrangements, Rare Variants (RVs), and more especially the biomarkers identified in table 1 (or diagnostically and predicatively functionally comparable biomarkers), preferably via a statistical assessment method such as MultiDimensional Scaling analysis (MDS), logistic regression, or Bayesian analysis. The markers and related statistical data shown in table 1 were discovered by analyzing a number of endometriosis cases and controls much as has been described in the prior patent applications incorporated herein by reference. It is noted that all of the biomarkers of table 1, being variations or mutations in and of the same structure (i.e. the human genome), share a single structural similarity in that all of the biomarkers of table 1 are endometriosis associated nucleotide substitutions of the same DNA sequence—the human genome DNA sequence, and that the common use of endometriosis diagnosis and prognosis of all of the biomarkers of table 1 flow from such single structural similarity. The present invention further preferably includes the treatment of a subject determined to have or be predisposed to endometriosis by administering to such subject a therapeutic such as an OC that at least partially compensates for endometriosis or that prevents or reduces the severity of endometriosis that the subject would otherwise develop or that prevents endometriosis related complications, cancers, or associated disorders. It shall be noted that preventing or cancelling a procedure, especially an invasive procedure, such as a laparoscopy, that would otherwise have been performed on a subject but for the results of a (negative) diagnosis/prognosis disclosed herein being performed on said subject, shall be consider within the scope of treatment or the “administration of a therapeutic”.

It shall be noted that for the purposes of this application, a SNP is understood to be a genetic polymorphism having a Minor Allele Frequency (MAF) of at least 1% in a population (such as for instance the Caucasian population or the CEU population) and an RV is understood to be a genetic polymorphism having a Minor Allele Frequency (MAF) of less than 1% in a population (such as for instance the Caucasian population or the CEU population).

It shall be noted that “Linkage disequilibrium” or “LD” means that a particular combination of alleles (alternative nucleotides) or genetic markers at two or more different SNP (or RV) sites are non-randomly co-inherited (i.e., the combination of alleles at the different SNP (or RV) sites occurs more or less frequently in a population than the separate frequencies of occurrence of each allele or the frequency of a random formation of haplotypes from alleles in a given population). The term “LD” differs from “linkage,” which describes the association of two or more loci on a chromosome with limited recombination between them. LD is also used to refer to any non-random genetic association between allele(s) at two or more different SNP (or RV) sites. Therefore, when a SNP (or RV) is in LD with other SNPs (or RVs), the particular allele of the first SNP (or RV) often predicts which alleles will be present in those SNPs (or RVs) in LD. LD is generally, but not exclusively, due to the physical proximity of the two loci along a chromosome. Hence, genotyping one of the SNP (or RV) sites will give almost the same information as genotyping the other SNP (or RV) site that is in LD. Linkage disequilibrium is caused by fitness interactions between genes or by such non-adaptive processes as population structure, inbreeding, and stochastic effects.

It shall also be noted that LD is the non-random association of alleles adjacent loci. When a particular allele at one locus is found together on the same chromosome with a specific allele at a second locus—more often than expected if the loci were segregating independently in a population—the loci are in disequilibrium. This concept of LD is formalized by one of the earliest measures of disequilibrium to be proposed (symbolized by D). D, in common with most other measures of LD, quantifies disequilibrium as the difference between the observed frequency of a two-locus haplotype and the frequency it would be expected to show if the alleles are segregating at random. A wide variety of statistics have been proposed to measure the amount of LD, and these have different strengths, depending on the context. Although the measure D has the intuitive concepts of LD, its numerical value is of little use for measuring the strength of and comparing levels of LD. This is due to the dependence of D on allele frequencies. The two most common measures are the absolute value of D′ and r². The absolute value of D′ is determined by dividing D by its maximum possible value, given the allele frequencies at the two loci. The case of D′=1 is known as complete LD (or CLD). The measure r² is in some ways complementary to D′. An r² value of 1 indicates complete LD as well while an r² value of 0 indicates linkage equilibrium. Complete LD demonstrates complete dependency. In other words, in complete LD the number of counts of the minor allele in loci 1 corresponds to the counts of minor allele in loci 2. Although in complete LD the alleles themselves might be different the frequency of Minor allele in loci 1 will be equal to the frequency of Minor allele in loci 2. For example, in comparing two loci such as rs1 having (A/G) and rs2 having (G/C), if it is known that rs1 and rs2 are in complete LD, and if it is known that a person carries a genotype AG on rs1, then it is known that the genotype on rs2 is GC for that person. Similarly in complete LD, if A is the minor allele of rs1 and is associated with the disease (or conversely is not associated with the disease) then the corresponding minor allele of rs² is also associated with the disease (or conversely or is not associated with the disease). Furthermore in complete LD, in any analysis of the disease, genotype for rs1 could easily be substituted for rs2 and vice versa.

In yet another embodiment, the invention also provides a kit comprising SNP detection reagents, and methods for detecting the SNPs disclosed herein by employing detection reagents and a questionnaire of non-genetic clinical factors. In one embodiment, the questionnaire would be completed by a medical professional based on medical history physical exam or other clinical findings. In yet another embodiment, the questionnaire would include any other non-genetic clinical factors known to be associated with the risk of developing endometriosis.

In yet another embodiment, the novel SNPs disclosed in '754 as well as other genetic markers are used in the selection of patients to whom a therapeutic will be administered based on the patient's assessed risk of developing endometriosis or based on the patient's assessed risk of endometriosis progression. The administered therapeutic may preferably be a patient specific gene or protein based therapy enabled and informed by SNPs discovered to be associated with endometriosis. Further, the administered therapeutic may be any of a hormonal treatment such as an estrogen containing composition, a progesterone containing composition, a progestin containing composition, a gonadotropin releasing-hormone (GnRH) agonist, or other ovulation suppression composition, or a combination thereof. In particular, the therapeutic may be administered in the form of an OC. Furthermore, the GnRH therapeutic may take the form of a GnRH agonist in combination with a patient specific substantially low dose of estrogen, progestin, or tibolone. Such administration of a low dose of estrogen, progestin, or tibolone in combination with a GnRH agonist to compensate potential side effects of the GnRH agonist are commonly referred to as an “add-back” therapy. It is noted that in such add-back therapy, the dosage of estrogen, progestin, or tibolone is relatively small so as to not reduce the effectiveness of the GnRH agonist.

It shall also be noted that unless indicated otherwise, when a genetic marker (e.g. SNP or RV) is identified as the genetic marker associated with a disease (in this instance endometriosis), it shall be understood that it is the minor allele (MA) of the particular genetic marker that is associated with the disease. Further it shall also be noted that unless indicated otherwise, if the Odds Ratio (OR) of the MA is greater than 1.0, the MA of the genetic marker (in this instance the endometriosis associated genetic marker) is correlated with an increased risk of endometriosis in a case subject as compared to a control subject and shall be considered a causative marker (C), and if the OR of the MA less than 1.0, the MA of the genetic marker is correlated with a decreased risk of endometriosis in a case subject as compared to a control subject and shall be considered a protective marker (P).

It shall also be noted that unless indicated otherwise, the phrase “functional equivalent” as used herein with respect to biomarkers shall mean that a second biomarker is substantially equivalent in its diagnostic and/or prognostic value with respect to a given disease as is a first biomarker's diagnostic and/or prognostic value with respect to the given disease. A second biomarker that is in complete LD with a first biomarker shall be expressly included within the scope of “functional equivalent” with respect to the relationship between the second biomarker to the first biomarker.

DESCRIPTION OF DRAWINGS

In order that the advantages of the invention will be readily understood, a more particular description of the invention briefly described above will be rendered by reference to specific embodiments that are illustrated in the appended drawings. Understanding that these drawings depict only typical embodiments of the invention and are not therefore to be considered to be limiting of its scope, the invention will be described and explained with additional specificity and detail through the use of the accompanying drawings, in which:

FIG. 1 depicts a “Three Endometriosis Related Clinical Questions” chart, and;

FIG. 2 depicts an “Endometriosis Clinical Factor Assessment” chart.

DETAILED DESCRIPTION OF THE INVENTION

The method of determining predisposition to endometriosis for a patient is performed according to the following steps. In a first step, answers to the FIG. 1 questions are obtained for the patient. In a second step, an RCPV according to FIG. 2 is determined for the patient based on the answers obtained for the patient in step 1. In an optional third step, the RCPV is optionally multiplied by an RF or otherwise adjusted according to the patient's age and race or according to relevant population survey data to result in a FCPV. In a fourth step, at least one endometriosis associated biomarker preferably drawn from the biomarkers of table 1 is identified in genetic material of the patient. In a fifth step, at least one statistical analysis (preferably MDS) is performed to combine the RCPV (or the FCPV) and the predictive value of the identified genetic biomarker to result in a highly predictive endometriosis prognosis or diagnosis.

“Oral contraceptives” or OCs are contraceptives that are commonly taken orally for the principal purpose of the prevention of conception. Such contraceptives are also commonly referred to as “Oral Contraceptive Pills” or OCPs, or simply as the “Pill”. Such OCs typically define a substance in pill form being comprised at least partially of estrogen, progesterone, or a combination thereof. The progesterone component may further be any of Desogestrel, Drospirenone, Ethynodiol, Levonorgestrel, Norethindrone, Norgestimate, and Norgestrel, and the estrogen component may further be any of Mestranol, Estradiol, and Ethinyl. Exemplary OCs that are commercially available are sold under the following names: ALESSE, APRI, ARANELLE, AVIANE, BREVICON, CAMILA, CESIA, CRYSELLE, CYCLESSA, DEMULEN, DESOGEN, ENPRESSE, ERRIN, ESTROSTEP, JOLIVETTE, JUNEL, KARIVA, LEENA, LESSINA, LEVLEN, LEVORA, LOESTRIN, LUTERA, MICROGESTIN, MICRONOR, MIRCETTE, MODICON, MONONESSA, NECON, NORA, NORDETTE, NORINYL, NOR-QD, NORTREL, OGESTREL, ORTHO-CEPT, ORTHO-CYCLEN, ORTHO-NOVUM, ORTHO-TRI-CYCLEN, OVCON, OVRAL, OVRETTE, PORTIA, PREVIFEM, RECLIPSEN, SOLIA, SPRINTEC, TRINESSA, TRI-NORINYL, TRIPHASIL, TRIVORA, VELIVET, YASMIN, AND ZOVIA (the preceding names are the registered trademarks of the respective providers).

“Gonadotropin releasing-hormone (GnRH) agonists” are a group of drugs that are useful in treating patients having endometriosis. Such drugs are modified versions of a naturally occurring hormone known as gonadotropin releasing hormone, which helps to control the menstrual cycle. Administration of such drugs is known to be performed in combination with an “add-back” therapy. In this case, an add-back therapy could be for instance the administration of a low dose of estrogen, progestin, or tibolone in combination with a GnRH agonist to compensate potential side effects of the GnRH agonist. It is noted that in such add-back therapy, the dosage of estrogen, progestin, or tibolone is relatively small so as to not reduce the effectiveness of the GnRH agonist.

The present invention provides SNPs associated with endometriosis, nucleic acid molecules containing SNPs, methods and reagents for the detection of the SNPs disclosed herein, uses of these SNPs for the development of detection reagents, and assays or kits that utilize such reagents. The SNPs disclosed herein are useful for diagnosing, screening for, and evaluating predisposition to endometriosis and progression of endometriosis. Additionally, such SNPs are useful in the determining individual subject treatment plans and design of clinical trials of devices for possible use in the treatment of endometriosis. Furthermore, such SNPs and their encoded products are useful targets for the development of therapeutic agents. Furthermore, such SNPs combined with other non-genetic clinical factors are useful for diagnosing, screening, evaluating predisposition to endometriosis, assessing risk of progression of endometriosis, determining individual subject treatment plans and design of clinical trials of devices for possible use in the treatment of endometriosis. Furthermore, such SNPs and are useful in the selection of recipients for an OC type therapeutic.

Therefore, the invention disclosed herein further teaches a method of selectively administering a therapeutic. Such method of administering a therapeutic preferably includes the following steps: a) Obtaining a genetic material sample of a human female subject, b) Identifying in the genetic material of the subject preferably at least one of the SNPs disclosed in '754 or alternatively identifying any other genetic marker having an association with endometriosis, c) Assessing the subject's risk of endometriosis or risk of endometriosis progression, d) Identifying the subject as having an altered risk of endometriosis or an altered risk of endometriosis progression, and e) administering to the subject a therapeutic. It is noted that the subject may be endometriosis presymptomatic or the subject may exhibit endometriosis symptoms. It is also noted that the assessment of risk may also include non-genetic clinical factors. The therapeutic may be a gene or protein based therapy adapted to the specific needs of a select patient. The therapeutic may alternatively take the form of a testosterone or a modified testosterone such as Danazol. Alternatively, the therapeutic defines a hormonal treatment therapeutic which may be administered alone or in combination with a gene therapy. For instance, the therapeutic may be an estrogen containing composition, a progesterone containing composition, a progestin containing composition, a gonadotropin releasing-hormone (GnRH) agonist, or other ovulation suppression composition, or a combination thereof. Additionally, the GnRH agonist may take the form of a GnRH agonist in combination with a patient specific substantially low dose of estrogen, progestin, or tibolone via an add-back administration. It is further noted that the therapeutic is preferably an OC. The OC preferably defines a substance in pill form that is comprised at least partially of estrogen, progesterone, or a combination thereof. The progesterone component may further be any of Desogestrel, Drospirenone, Ethynodiol, Levonorgestrel, Norethindrone, Norgestimate, and Norgestrel, and the estrogen component may further be any of Mestranol, Estradiol, and Ethinyl. Specifically, the OC may be any commercially available OC including ALESSE, APRI, ARANELLE, AVIANE, BREVICON, CAMILA, CESIA, CRYSELLE, CYCLESSA, DEMULEN, DESOGEN, ENPRESSE, ERRIN, ESTROSTEP, JOLIVETTE, JUNEL, KARIVA, LEENA, LESSINA, LEVLEN, LEVORA, LOESTRIN, LUTERA, MICROGESTIN, MICRONOR, MIRCETTE, MODICON, MONONESSA, NECON, NORA, NORDETTE, NORINYL, NOR-QD, NORTREL, OGESTREL, ORTHO-CEPT, ORTHO-CYCLEN, ORTHO-NOVUM, ORTHO-TRI-CYCLEN, OVCON, OVRAL, OVRETTE, PORTIA, PREVIFEM, RECLIPSEN, SOLIA, SPRINTEC, TRINESSA, TRI-NORINYL, TRIPHASIL, TRIVORA, VELIVET, YASMIN, AND ZOVIA (the preceding names are the registered trademarks of the respective providers). It is further noted that the therapeutic may comprise any other ovulation suppression substance. It is further noted that the therapeutic is preferably adapted to the specific subject so as to be a proper and effective amount of therapeutic for the subject. It is further noted that the administration of the therapeutic may comprise multiple sequential instances of administration of the therapeutic and that such sequence instances may occur over an extended period of time or may occur on an indefinite on-going basis.

It shall be noted that the markers of table 1 are drawn from build 37 data (or “GRCh37” as defined by the Genome Reference Consortium) and that in the header of table 1: “Set” corresponds to a particular subset (i.e. subset 01, subset 02, or subset 03) of the biomarkers of table 1, “Name” corresponds to a name for a given biomarker and where possible is the reference SNP number (rs) of the particular biomarker, but if not possible then it is the exome variant number (exm) of the particular biomarker (as assigned by Illumina, Incorporated), but if not possible then it is a “JBL” number assigned by applicant, “Chr” corresponds to the chromosome where a given biomarker is located in the human genome, “Arm” corresponds to the arm of the chromosome where a given biomarker is located in the human genome, “Cyto” corresponds to the cytoband of the arm of the chromosome where a given biomarker is located in the human genome, “Gene” corresponds to the gene where a given biomarker is located in the human genome or alternatively if the biomarker is not located within a gene, “Gene” corresponds to the nearest two genes positioned on either side of the given biomarker in the human genome, “position” corresponds to the position of a given biomarker in the human genome, “p-value” corresponds to the p-value of a given biomarker, “OR” corresponds to the Odds Ratio of a given biomarker, “Case MAF” corresponds to the case Minor Allele Frequency of a given biomarker, “Cont MAF” corresponds to the control Minor Allele Frequency of a given biomarker, “MA” corresponds to the Minor Allele of a given biomarker, and “Context Sequence” corresponds to the context sequence in which a given biomarker is located and provides a SEQ ID NO and the identification of the biomarker variation of substitution (e.g. “A/C” or “A/G”, etc.). It shall be further noted that values for p-value, OR, Case MAF, and Cont MAF provided in Table 1 were derived by applicant using predetermined statistical methods and a predetermined group of cases and controls, and that while others who might analyze the same set of data may arrive at similar but not necessarily identical results if the identical analytical methods are not used. Moreover, it is believed that substantially similar results would occur based on a similar analysis performed on data drawn from different populations that used herein.

TABLES

TABLE 1 (Based on build 37 or “GRCh37” as fined by the Genome Reference Consortium) p- Case Cont Set Name Chr Arm Cyto Gene Position value OR MAF MAF MA Context Sequence 03 rs7521023 1 p p13.1 CASQ2 116243380 7.63E− 1.11 0.435 0.409 G (SEQ ID NO: 0001) 05 aaggatcatcttggct[A/G] gaggagggatcccaac 03 rs3811012 1 p p13.1 VANGL1 116234313 8.03E− 1.11 0.425 0.399 A (SEQ ID NO: 0002) 05 cctcgccttacaacta[A/G] ttcctgcctttcgtcc 03 rs1373291 1 p p13.2 KCND3 112426851 4.79E− 1.14 0.214 0.192 A (SEQ ID NO: 0003) 04 gagaattgagttgaaa[A/C] tttaaagaaggagttg 03 rs3008527 1 p p13.2 KCND3 112523095 2.53E− 0.90 0.253 0.274 G (SEQ ID NO: 0004) 03 gccaaaacccagaggc[A/G] atagtgttggtttttc 03 rs3827735 1 p p13.2 TRIM33 115052708 2.52E− 1.19 0.130 0.112 A (SEQ ID NO: 0005) 04 ccatttaatccatagt[A/C] ctcctctctcctatct 03 rs2640493 1 p p13.3 KCNA2| 111187885 2.04E− 1.13 0.340 0.313 A (SEQ ID NO: 0006) KCNA3 04 gcacatgaaagtttaa[A/G] tagcactactaccaga 03 rs17113362 1 p p21.3 LOC  95782971 7.57E− 1.32 0.039 0.030 A (SEQ ID NO: 0007) 729977 04 tcatgaactatgtagg[A/G] aaggaagtgaaatttg 02 rs4658172 1 p p22.2 BARHL2|  91225594 1.11E− 1.16 0.327 0.296 G (SEQ ID NO: 0008) ZNF644 05 gaaacaactgctcagg[A/G] cattttgcaaatttac 02 rs6656775 1 p p22.2 BARHL2|  91219359 5.36E− 1.16 0.345 0.311 G (SEQ ID NO: 0009) ZNF644 06 atcctttctcagcagg[A/G] cccattatttctcatt 02 rs1526480 1 p p22.2 BARHL2|  91209986 7.16E− 1.15 0.408 0.374 G (SEQ ID NO: 0010) ZNF644 06 acagatagttcctatg[A/G] gctagacttggtcaga 01 rs6699397 1 p p22.2 BARHL2|  91212216 3.32E− 1.16 0.405 0.370 G (SEQ ID NO: 0011) ZNF644 06 gaactgcatagtccca[A/G] cttacaaagaatcagc 03 rs13376108 1 p p22.2 GTF2B  89350741 1.15E− 1.30 0.024 0.018 G (SEQ ID NO: 0012) 02 agagcttagtagcttc[A/G] acagaaaccacatgtg 03 rs3008445 1 p p22.2 LMO4|  88446605 2.37E− 0.91 0.432 0.456 A (SEQ ID NO: 0013) PKN2 03 agtaatagacatttac[A/G] tttcctccaggttttt 03 rs3008453 1 p p22.2 LMO4|  88427851 8.00E− 1.09 0.505 0.484 A (SEQ ID NO: 0014) PKN2 03 tctagagttaaatcct[A/G] tctggggactctgggc 03 rs4537535 1 p p22.2 ZNF326|  91080115 7.52E− 1.09 0.503 0.482 G (SEQ ID NO: 0015) BARHL2 03 cactcagaagagagta[A/G] ctagagtaagaagtca 03 rs7527341 1 p p31.1 LOC  82009424 8.91E− 0.95 0.334 0.347 A (SEQ ID NO: 0016) 729817| 05 gaaatgggaaactatc[A/G] LPHN2 tagggttctttgcaga 02 exm68565 1 p p31.1 TNNI3K  74808620 8.37E− Inf 0.005 0.000 C (SEQ ID NO: 0017) 13 tgctgcaaagtgattt[C/G] gaagttcaacctcatg 03 rs17130484 1 p p31.3 GPR177  68581840 2.95E− 0.77 0.048 0.062 C (SEQ ID NO: 0018) 04 gctgctcctggtccct[A/C] ttgtaaggtcctgtga 02 rs6693065 1 p p31.3 IL12RB2  67800018 3.19E− 1.08 0.244 0.231 G (SEQ ID NO: 0019) 05 gatcatacgatctgtc[A/G] caactgctaaatgtgc 03 rs4255357 1 p p31.3 PDE4B  66399895 8.47E− 1.11 0.487 0.461 G (SEQ ID NO: 0020) 04 gagtaagacataggag[A/G] tcaaggtaggaggatt 03 rs11208775 1 p p31.3 PDE4B  66410541 6.36E− 1.11 0.487 0.460 G (SEQ ID NO: 0021) 04 atttatcatgttctct[A/G] gtaggaatgctcccca 03 rs7554648 1 p p32.1 FGGY|  60238762 5.87E− 1.17 0.087 0.075 A (SEQ ID NO: 0022) HOOK1 03 aaaatctcagctccac[A/C] tcagccccaattatct 03 rs11805025 1 p p32.2 DAB1  57850717 4.08E− 0.89 0.195 0.214 C (SEQ ID NO: 0023) 03 tatacagaaacacaaa[A/C] cccatcttggatcact 03 rs778406 1 p p32.2 USP24|  56703505 7.87E− 1.17 0.067 0.058 A (SEQ ID NO: 0024) LOC 05 tattaatctttttcac[A/C] 100288320 tcagcacagcagaact 03 rs12758665 1 p p32.3 USP24|  55839117 3.79E− 0.87 0.196 0.218 A (SEQ ID NO: 0025) LOC 04 ttcgtaactacgatga[A/C] 100288320 tttctcggttaagagt 03 rs7520205 1 p p32.3 USP24|  55834309 1.30E− 0.86 0.190 0.215 A (SEQ ID NO: 0026) LOC 04 agttttgtttcacagg[A/G] 100288320 ctaaagcctgaacaga 01 exm49794 1 p p34.2 CITED4  41327281 5.28E− 21.6 0.056 0.035 A (SEQ ID NO: 0027) 60 2 cgggcggcgcggaccc[A/C] aagtccgagaagcagt 03 rs219007 1 p p34.3 CSF3R|  37147203 5.68E− 1.10 0.395 0.372 A (SEQ ID NO: 0028) GRIK3 05 aaaaagaatcagaaat[A/G] tctggtgcatggagcc 02 rs2484556 1 p p34.3 LOC  37913283 4.34E− 0.89 0.342 0.367 A (SEQ ID NO: 0029) 100287202| 05 gacctccagcaggggc[A/G] LOC728431 tggccagtgggtgcca 03 rs4970614 1 p p34.3 POU3F1|  39135748 8.84E− 0.84 0.103 0.120 A (SEQ ID NO: 0030) LOC400750 04 tagtttccctggaaac[A/G] tatatctttgtacact 01 rs9438994 1 p p34.3 RHBDL2  39388838 3.11E− 1.23 0.158 0.132 G (SEQ ID NO: 0031) 06 gtgcaatgtatgaggt[A/G] taaattaatgcagcct 02 rs6422258 1 p p34.3 RHBDL2  39406644 9.56E− 1.21 0.118 0.099 A (SEQ ID NO: 0032) 05 ttattttggagtcaca[A/G] agacacttggcttttt 02 rs4475740 1 p p34.3 RHBDL2|  39425489 9.29E− 1.23 0.101 0.084 A (SEQ ID NO: 0033) AKIRIN1 05 gtgctctagctgcaag[A/G] caggtggaaaaagtgt 02 rs1138294 1 p p36.11 MAP3K6  27688633 2.76E− 0.89 0.339 0.366 A (SEQ ID NO: 0034) 05 agccagcaccacctgg[A/G] tggggtcattggcgag 03 rs443523 1 p p36.11 RUNX3|  25403783 9.12E− 1.12 0.288 0.265 A (SEQ ID NO: 0035) SYF2 04 gtttgctctcactctt[A/C] atacaatcgccaaaat 03 rs292005 1 p p36.12 C1QB|  22993335 1.60E− 0.93 0.460 0.479 C (SEQ ID NO: 0036) EPHB2 02 taggggatctcattgc[A/C] cagtaaaataggcgac 03 rs7549747 1 p p36.12 C1QB|  22996571 3.37E− 0.91 0.395 0.418 G (SEQ ID NO: 0037) EPHB2 03 gttccattttgtagcc[A/G] aggatataaaagctca 03 rs294218 1 p p36.12 C1QB|  23033257 1.04E− 1.09 0.393 0.373 C (SEQ ID NO: 0038) EPHB2 02 agagacttgggtacac[A/C] gagaggggatgtctat 03 rs294214 1 p p36.12 C1QB|  23026293 4.51E− 1.10 0.315 0.294 A (SEQ ID NO: 0039) EPHB2 03 gggcggaggggaggcg[A/G] gagatttctgagctcc 03 rs12734877 1 p p36.12 C1QC|  22977883 9.54E− 0.95 0.408 0.421 C (SEQ ID NO: 0040) C1QB 02 cactgcttctacccca[A/C] attgacatccatcttt 01 rs1534949 1 p p36.12 CDC42|  22426187 2.18E− 1.16 0.441 0.405 C (SEQ ID NO: 0041) LOC 06 tgagagaatatgacac[A/C] 100289113 ttcttcctttagagga 01 rs2473277 1 p p36.12 HSPC157|  22361845 1.77E− 1.16 0.508 0.471 G (SEQ ID NO: 0042) CDC42 06 gctatacctcccaatc[A/G] tcaacctgtagaacat 01 rs4654783 1 p p36.12 LOC  22439520 2.16E− 1.22 0.337 0.294 A (SEQ ID NO: 0043) 100289113| 09 tgctggtcaggatgga[A/G] WNT4 tatgttatcagagccc 01 rs2235529 1 p p36.12 WNT4  22450487 4.66E− 1.32 0.189 0.150 A (SEQ ID NO: 0044) 12 agaaccaggtagagaa[A/G] gctggaggagccgcca 02 rs7544210 1 p p36.12 WNT4  22455142 6.02E− 1.15 0.463 0.428 G (SEQ ID NO: 0045) 06 acagcgtctcctcatc[A/G] aggataagaccacaga 02 rs1046310 1 p p36.12 WNT4|  22443887 7.78E− 1.15 0.492 0.457 C (SEQ ID NO: 0046) LOC 06 tgctgccccaccccat[A/C] 100289113 ctccaatttttatact 02 rs3765351 1 p p36.12 WNT4|  22445991 1.14E− 1.15 0.487 0.452 G (SEQ ID NO: 0047) LOC 05 aggtcaagggcaccag[A/G] 100289113 ttcatttcagccctta 01 rs12042083 1 p p36.12 WNT4|  22472732 4.84E− 1.21 0.231 0.199 A (SEQ ID NO: 0048) ZBTB40 07 aattcttaatgagaaa[A/G] tctcttggaggaaatg 01 rs4623666 1 p p36.12 WNT4|  22480312 3.96E− 1.16 0.440 0.405 G (SEQ ID NO: 0049) ZBTB40 06 atgcacacagaagccc[A/G] gccggtatccccacag 02 rs221047 1 p p36.13 ARHGEF19  16530364 4.01E− 1.15 0.155 0.137 G (SEQ ID NO: 0050) 05 ccctgatgatatggtt[A/G] tcagaatgtattttca 03 rs12088541 1 p p36.22 MAD2L2  11751135 5.77E− 0.83 0.093 0.110 A (SEQ ID NO: 0051) 04 ggttctccgagaggtc[A/G] ctcctggatgtagggg 03 rs641941 1 p p36.22 TNFRSF8|  12206652 4.79E− 1.09 0.495 0.473 G (SEQ ID NO: 0052) TNFRSF1B 03 actggctcattattcg[A/G] cgtctgtaactctggg 03 rs17349921 1 p p36.31 CAMTA1   7170719 7.70E− 1.09 0.101 0.094 G (SEQ ID NO: 0053) 05 aatgagtgttcttaga[A/G] gctgggtcggattcct 03 rs10915329 1 p p36.32 AJAP1|   5114102 2.26E− 1.10 0.431 0.407 A (SEQ ID NO: 0054) LOC 03 tcagacctgggagaat[A/G] 100287877 tcaggtaagctgagat 01 JBL0002 1 p p36.33 RNF223   1007306 6.27E− 6.76 0.020 0.005 A (SEQ ID NO: 0055) 05 5 gagcgcgcactgcacc[G/A] gccagagtgccacaca 02 exm91506 1 q q21.1 ANKRD35 145560893 4.73E− 18.9 0.004 0.000 C (SEQ ID NO: 0056) 08 0 cttttcttataggtca[C/G] aggctagtccagcacc 02 exm90634 1 q q21.1 PDE4DIP 144931581 6.11E− Inf 0.004 0.000 G (SEQ ID NO: 0057) 12 ctcggctttgccatcg[C/G] gggggacatccttgcc 02 exm90788 1 q q21.1 SEC22B 145115792 1.20E− 3.71 0.011 0.000 A (SEQ ID NO: 0058) 13 catgttcaagtacttc[A/G] catcctggcggtattt 03 rs11204684 1 q q21.3 ENSA| 150608894 4.02E− 1.12 0.481 0.454 A (SEQ ID NO: 0059) GOLPH3L 04 gttggggagtgagcca[A/G] cagttatctggaggga 03 rs10888510 1 q q21.3 LCE4A 152681835 1.53E− 1.56 0.019 0.012 A (SEQ ID NO: 0060) 04 tcagcaacagccccct[A/C] cagagcagcagccaga 03 rs4970972 1 q q21.3 TARS2 150468547 1.65E− 1.26 0.072 0.058 A (SEQ ID NO: 0061) 04 catatcccattcctgg[A/C] cacatgaaatccaaaa 03 rs16838078 1 q q23.1 ETV3L 157069261 2.43E− 1.31 0.032 0.025 C (SEQ ID NO: 0062) 03 ccaagaggctcacctg[A/C] gatccagttgccgggg 03 rs4656849 1 q q23.2 CRP| 159723521 2.04E− 0.90 0.361 0.385 A (SEQ ID NO: 0063) DUSP23 03 aagggtcagaaaacaa[A/G] taaaaggccaagacag 03 rs3897374 1 q q23.3 NOS1AP 162168958 7.13E− 1.03 0.178 0.174 G (SEQ ID NO: 0064) 05 caaacctccttgagtc[A/G] gctttaagagtttctt 02 exm129317 1 q q25.3 RGS16 182571142 7.34E− 13.6 0.004 0.000 C (SEQ ID NO: 0065) 08 5 aactcctcaaagatct[C/G] gtgtgccctggaggcc 03 rs10921412 1 q q31.2 CDC73| 193661626 1.36E− 1.11 0.361 0.337 A (SEQ ID NO: 0066) KCNT2 03 gaagttttttacaacc[A/G] aaatctatgaccgttg 02 exm133014 1 q q31.2 GLRX2 193074511 1.85E− 4.14 0.023 0.006 G (SEQ ID NO: 0067) 17 cgcgcggcgccaaatc[A/G] tggtcagagcccggat 02 rs6701700 1 q q31.2 RGS1| 192556309 7.80E− 1.20 0.133 0.113 A (SEQ ID NO: 0068) RGS13 05 aaggaattaccaagaa[A/G] agccatgcatctcaca 03 rs10489873 1 q q31.2 RGS1| 192559646 2.31E− 1.25 0.076 0.062 A (SEQ ID NO: 0069) RGS13 04 ccgggaagtgcacgct[A/G] ccaccgaggagccatc 03 rs17466945 1 q q32.1 CHI3L1| 203183093 1.62E− 1.16 0.131 0.116 C (SEQ ID NO: 0070) CHIT1 03 gatgagatcccaagtc[A/C] aaggaagatttgccca 03 rs6662930 1 q q32.1 CNTN2 205041465 7.66E− 0.92 0.451 0.472 G (SEQ ID NO: 0071) 03 cgaaacaaagcccatg[A/G] aaatccaaaggttgga 02 rs880790 1 q q32.1 IL10| 206960216 1.83E− 1.17 0.249 0.220 G (SEQ ID NO: 0072) IL19 05 gcttgggggctggaga[A/G] cagaatttaacatgtt 03 rs17434403 1 q q32.1 RASSF5 206737276 4.07E− 0.87 0.116 0.131 C (SEQ ID NO: 0073) 03 ttcaaggccctttgag[A/C] tcttgatggcacatga 03 rs4570460 1 q q32.1 SYT2| 202689028 1.29E− 1.33 0.034 0.025 A (SEQ ID NO: 0074) KDM5B 03 agtatattaggggatt[A/G] atattacaagcaagaa 03 rs6670957 1 q q32.2 PLXNA2| 209195248 4.01E− 1.21 0.063 0.053 A (SEQ ID NO: 0075) LOC642587 03 gctgtatgttataatt[A/C] tctgatagaacccaca 02 rs11119874 1 q q32.3 DTL| 212357017 4.15E− 1.11 0.189 0.173 A (SEQ ID NO: 0076) PPP2R5A 05 gatgaaataatagact[A/C] cagggatttacttttt 03 rs2359937 1 q q32.3 RPS6KC1| 214033051 1.14E− 0.92 0.478 0.497 G (SEQ ID NO: 0077) PROX1 02 actctccaaagtcaca[A/G] tattttctggacaagc 02 rs2789939 1 q q41 DISP1| 223191495 2.07E− 0.86 0.281 0.311 C (SEQ ID NO: 0078) TLR5 03 atcaggatcataggag[C/G] actgtctgaggatcag 02 rs12747035 1 q q41 PTPN14 214719346 5.58E− 1.12 0.385 0.359 G (SEQ ID NO: 0079) 06 acctggctagggatac[A/G] aggccattaaccaagc 02 rs903695 1 q q42.13 CDC42BPA| 227733069 2.19E− 1.18 0.211 0.185 C (SEQ ID NO: 0080) ZNF678 03 tggttgttgcatggca[T/C] ttccagataagctgca 03 rs2493142 1 q q42.2 COG2 230817384 5.27E− 1.11 0.262 0.243 G (SEQ ID NO: 0081) 03 aatgtttgtatttggg[A/G] ttgcccttcttacatg 01 rs3789649 1 q q42.2 COG2 230816460 8.83E− 1.21 0.227 0.195 A (SEQ ID NO: 0082) 07 caagttctacacttcc[A/G] taactcaaacgtgttt 03 rs1693210 1 q q42.2 KCNK1 233800613 1.98E− 1.11 0.382 0.359 A (SEQ ID NO: 0083) 03 tcaattataatcacct[A/G] tgtggatttttctcag 02 rs7545302 1 q q43 FMN2 240476158 9.75E− 0.92 0.243 0.258 A (SEQ ID NO: 0084) 06 cgaactgatcagatcg[A/C] tgccctacacacttta 03 rs6699695 1 q q43 RGS7|FH 241539802 6.47E− 1.10 0.325 0.305 A (SEQ ID NO: 0085) 03 caaatattactgcaat[A/G] agtaatatcatacaca 03 rs987179 1 q q44 C1orf101| 244809936 7.12E− 0.87 0.256 0.283 A (SEQ ID NO: 0086) PPPDE1 05 aacagatgccatggta[A/G] actagatgcctgggtg 03 rs7548336 1 q q44 LOC440742| 244401066 6.04E− 1.12 0.423 0.397 G (SEQ ID NO: 0087) C1orf100 04 tctttaaggtgggttc[A/G] gagaaaggagatggaa 03 rs900895 1 q q44 LOC440742| 244510437 1.38E− 1.15 0.156 0.138 A (SEQ ID NO: 0088) C1orf100 03 acagacagggtgtcat[A/G] gaagccgcgtcatatc 03 rs3755095 2 p p12 CTNNA2  80097279 1.16E− 1.19 0.098 0.084 G (SEQ ID NO: 0089) 03 tccaccagtgaagcaa[A/G] taatctgtggcctgct 03 rs953222 2 p p12 CTNNA2  79979967 3.88E− 1.14 0.135 0.120 A (SEQ ID NO: 0090) 03 caaaaaagaagtatca[A/G] ggtatatatgaagaga 03 rs6547260 2 p p12 CTNNA2  79925969 4.27E− 1.18 0.137 0.119 A (SEQ ID NO: 0091) 04 aacagaaaattaagat[A/C] agattggctaacaaga 03 rs1160581 2 p p12 CTNNA2  80026432 1.33E− 1.14 0.284 0.257 G (SEQ ID NO: 0092) 04 taaaggaatccctgtt[A/G] aaaaaaaagaataagg 03 rs4284854 2 p p12 CTNNA2  80025940 1.47E− 1.15 0.264 0.238 A (SEQ ID NO: 0093) 04 tttcctttataaaact[A/G] tgttactctagtctga 03 rs2861911 2 p p12 CTNNA2  80007717 5.79E− 1.11 0.208 0.191 G (SEQ ID NO: 0094) 03 ctaaatggtggttcac[A/G] gggaattcatgaaact 03 rs1397687 2 p p12 CTNNA2  80015386 6.22E− 1.10 0.253 0.235 A (SEQ ID NO: 0095) 03 gggagctcagactcac[A/G] tggtggaaagcctaaa 03 rs6732862 2 p p12 CTNNA2  79918572 7.64E− 1.16 0.239 0.213 A (SEQ ID NO: 0096) 05 atggcataacaatagt[A/G] actcaaagaggcaaaa 03 rs4852536 2 p p12 CTNNA2  80104027 1.02E− 1.16 0.086 0.076 G (SEQ ID NO: 0097) 02 tttggaaatttaacac[A/G] tgaatataaccatcaa 03 rs1265750 2 p p12 CTNNA2|  80951823 2.64E− 1.10 0.169 0.157 A (SEQ ID NO: 0098) LOC 02 aacaggactaagtggc[A/G] 100289658 tataaattagggtaat 02 rs1443896 2 p p12 LRRTM1|  80572750 8.14E− 1.41 0.045 0.032 A (SEQ ID NO: 0099) CTNNA2 06 tatatcatcagtgccc[A/G] gaagagtacctgatgc 03 rs1239102 2 p p12 SNAR-H|  78873621 1.21E− 1.13 0.367 0.338 G (SEQ ID NO: 0100) REG3G 04 accagtaccatccggt[A/G] tgatttgatggtatga 03 rs11687801 2 p p12 SNAR-H|  78978011 2.30E− 1.13 0.329 0.302 A (SEQ ID NO: 0101) REG3G 04 tgatgaggccttctcg[A/G] ggaagttttacgatgt 02 exm204635 2 p p13.1 CCDC142  74709541 8.09E− Inf 0.005 0.000 A (SEQ ID NO: 0102) 13 tgcagctgcaggtcgc[A/G] gcaccactggggcaag 03 rs879511 2 p p13.2 SFXN5  73179990 4.99E− 1.48 0.020 0.014 G (SEQ ID NO: 0103) 04 actcagccccagcccc[A/G] ctcactaagctcacag 03 rs2312205 2 p p13.3 AAK1  69704941 1.17E− 1.11 0.188 0.173 G (SEQ ID NO: 0104) 02 ccattgcaaaccacag[A/G] ggtgattatttttagt 03 rs3771452 2 p p13.3 ADD2  70936861 3.88E− 0.89 0.334 0.360 A (SEQ ID NO: 0105) 04 gggggaaagcgggaag[A/G] tctcttgctccaggaa 03 rs12466648 2 p p13.3 GFPT1  69560024 1.74E− 1.13 0.192 0.173 G (SEQ ID NO: 0106) 03 ggatgagactecctct[A/G] taataaaatcacagtc 03 rs12473304 2 p p13.3 GFPT1  69558112 1.02E− 1.15 0.178 0.159 A (SEQ ID NO: 0107) 03 ataaaatttatagtac[A/G] ttttgagcctgtgtgt 03 rs7605572 2 p p13.3 NFU1  69646504 2.19E− 1.14 0.177 0.159 A (SEQ ID NO: 0108) 03 aaacatagcatatttc[A/G] cttgattcttgtgaca 03 rs1430778 2 p p14 ETAA1|  68012459 4.27E− 0.91 0.312 0.333 G (SEQ ID NO: 0109) C1D 03 tgcttcaacaatttcc[A/G] tttgtgtatcgttggc 03 rs6727061 2 p p15 B3GNT2|  62720684 3.86E− 1.10 0.390 0.368 G (SEQ ID NO: 0110) TMEM17 03 tctgtgctgtttttca[A/G] ggaaaaacatctgggt 03 rs2674061 2 p p16.1 LOC730134|  59753331 1.58E− 1.11 0.319 0.296 A (SEQ ID NO: 0111) BCL11A 03 cccaagacactgtagc[A/G] tttacatagtaggtag 02 rs3814360 2 p p16.3 LOC  47800603 8.19E− 1.21 0.200 0.171 T (SEQ ID NO: 0112) 100653325 04 atgatcatgtgattga[A/T] gtatctaaaccacagt 02 rs989373 2 p p16.3 LOC646936|  49158325 1.12E− 0.86 0.334 0.368 A (SEQ ID NO: 0113) FSHR 05 gaacatatagacaatc[A/G] ggaatgctaaaataaa 03 rs1067352 2 p p21 C2orf34  44669724 7.70E− 0.89 0.290 0.314 A (SEQ ID NO: 0114) 04 gactccttgcatttca[A/G] tataatgttagctctg 03 rs1067339 2 p p21 C2orf34  44624448 3.83E− 0.91 0.310 0.331 A (SEQ ID NO: 0115) 03 atgcattgatgacctt[A/C] aatatttattttgtaa 03 rs1223222 2 p p21 C2orf34  44756361 1.30E− 0.92 0.319 0.338 C (SEQ ID NO: 0116) 02 atatcattatgaactc[A/C] tagattttttaaccta 03 rs1067350 2 p p21 C2orf34  44669946 2.56E− 0.89 0.227 0.247 A (SEQ ID NO: 0117) 03 ccagcagctcatcaga[A/G] agagggatgacagaca 03 rs1067386 2 p p21 C2orf34  44644257 3.92E− 0.91 0.311 0.332 C (SEQ ID NO: 0118) 03 acaacgcaatactact[A/C] gggaataaaaaggaaa 03 rs1067343 2 p p21 C2orf34  44621042 4.58E− 0.90 0.244 0.263 A (SEQ ID NO: 0119) 03 agtagtggaacgaaat[A/G] actttggagaaaagga 03 rs1067364 2 p p21 C2orf34  44655734 3.22E− 0.90 0.230 0.250 A (SEQ ID NO: 0120) 03 tccctgcctcctgtcc[A/G] tatcaatagatgttgg 03 rs1067405 2 p p21 C2orf34  44674861 3.81E− 0.90 0.240 0.260 A (SEQ ID NO: 0121) 03 actgacaacaggcttc[A/G] ccatgtaaattgctct 03 rs698793 2 p p21 C2orf34  44685685 3.74E− 0.90 0.241 0.260 G (SEQ ID NO: 0122) 03 taagatgaaaaggtct[A/G] ctttcaggggtttgtg 03 rs1067370 2 p p21 C2orf34  44652343 4.01E− 0.91 0.310 0.332 A (SEQ ID NO: 0123) 03 aacccagccattaact[A/C] ttgttagatagcttta 03 rs1067406 2 p p21 C2orf34  44674450 1.84E− 0.90 0.302 0.325 G (SEQ ID NO: 0124) 03 tccttttattctcctc[A/G] ttttatgtaattctgt 03 rs1065785 2 p p21 C2orf34  44660699 1.98E− 0.90 0.298 0.321 A (SEQ ID NO: 0125) 03 actttttgcttagtct[A/G] aattaaaaaaagtctt 03 rs698813 2 p p21 C2orf34  44705615 1.49E− 0.89 0.217 0.238 A (SEQ ID NO: 0126) 03 ttacaagattttcttt[A/G] gtttatagacctactt 03 rs698815 2 p p21 C2orf34  44706974 7.55E− 0.88 0.235 0.259 C (SEQ ID NO: 0127) 04 cttgtttggggacaca[A/C] tttcaaatacaaaatg 02 exm189795 2 p p21 PLEKHH2  43903164 1.13E− 10.0 0.020 0.002 C (SEQ ID NO: 0128) 27 9 tttttagtatcgtaga[C/G] ctctgctttgtcacag 03 rs6712059 2 p p21 PPM1B|  44475174 3.36E− 0.91 0.375 0.398 A (SEQ ID NO: 0129) SLC3A1 03 gactcaggtttgaggc[A/G] ttttgcatctggtggc 03 rs9309116 2 p p21 PREPL  44557919 6.27E− 0.89 0.331 0.357 G (SEQ ID NO: 0130) 04 gggaacaaattaatat[A/G] taaactatagccttga 03 rs4953089 2 p p21 PREPL  44565024 6.86E− 0.89 0.293 0.318 G (SEQ ID NO: 0131) 04 tccctgcatcccctgc[A/G] gataagaaaactggca 03 rs1056865 2 p p21 PREPL|  44546741 1.62E− 0.90 0.294 0.318 A (SEQ ID NO: 0132) SLC3A1 03 atagtatgtgttcatt[A/G] aagatgatttgggttt 03 rs698775 2 p p21 PREPL|  44588941 1.09E− 0.89 0.300 0.324 G (SEQ ID NO: 0133) C2orf34 03 agatggctaccagcaa[A/G] aatggtgcaatggcgt 02 rs7581914 2 p p21 PRKCE  46078964 4.68E− 0.88 0.391 0.423 G (SEQ ID NO: 0134) 05 tcatttattgcttgat[A/G] gacacctctaatgtat 03 rs2340809 2 p p21 SLC3A1  44536249 2.28E− 0.90 0.297 0.320 A (SEQ ID NO: 0135) 03 aaaagtgtgtaattca[A/G] tgcattaaatacattc 03 rs698761 2 p p21 SLC3A1  44547574 5.56E− 0.89 0.293 0.319 G (SEQ ID NO: 0136) 04 gccttcccgctaaaat[A/G] agaataaggttaagta 03 rs2112040 2 p p21 SRBD1  45752214 7.29E− 1.09 0.308 0.289 G (SEQ ID NO: 0137) 05 tgtcggtaggactact[A/G] gatagccacaggcaaa 03 rs10165323 2 p p22.2 LOC  38010296 1.28E− 0.87 0.154 0.173 A (SEQ ID NO: 0138) 100129149| 03 ttgtggtctgtgttta[A/G] LOC344382 gataatgtggaagcta 03 rs206811 2 p p23.1 XDH  31636915 2.30E− 1.13 0.381 0.354 A (SEQ ID NO: 0139) 04 ggagtggggggaatgc[A/G] ggagatgccctttatg 03 rs206816 2 p p23.1 XDH|  31644983 5.04E− 1.12 0.408 0.381 A (SEQ ID NO: 0140) SRD5A2 04 atgatgctgagaatct[A/G] tgaaatgacggaagaa 03 rs7575607 2 p p23.1 XDH|  31640455 1.69E− 1.11 0.413 0.389 G (SEQ ID NO: 0141) SRD5A2 03 tttattccttctatct[A/G] actgaaattctgtatt 03 rs2339554 2 p p23.2 ALK  29856155 7.90E− 0.89 0.272 0.296 A (SEQ ID NO: 0142) 04 acctcctgagctcaga[A/C] caagagtgcagccttt 02 rs2339547 2 p p23.2 ALK  29860061 3.38E− 0.88 0.239 0.263 A (SEQ ID NO: 0143) 05 gtttaatcatacatcc[A/G] tggaggaacatgttgg 03 rs6734278 2 p p23.3 KIF3C  26202233 1.70E− 1.21 0.112 0.095 A (SEQ ID NO: 0144) 04 ctctcagggttatggg[A/G] aattggatattaactg 02 rs2384298 2 p p23.3 KIF3C  26156655 2.63E− 1.15 0.291 0.263 G (SEQ ID NO: 0145) 06 actaatagtgtatgag[A/G] gtttcattttctctac 03 rs13029647 2 p p23.3 OTOF  26731244 7.95E− 1.09 0.369 0.349 A (SEQ ID NO: 0146) 03 ctaactgacattcaac[A/G] cactttcaaagacacc 02 rs13031859 2 p p23.3 OTOF  26741961 3.98E− 0.91 0.464 0.488 A (SEQ ID NO: 0147) 05 ttctgcagcaccatgc[A/G] gaaggtcccgatgagc 03 rs4665181 2 p p24.1 LOC  22759343 2.42E− 1.11 0.350 0.327 A (SEQ ID NO: 0148) 100129278| 03 gcgaaagaacaaacaa[A/G] KLHL29 ccatgtaatacatatg 02 rs851352 2 p p24.1 NT5C1B|  19475331 5.32E− 1.14 0.253 0.229 A (SEQ ID NO: 0149) OSR1 06 gccaggtctaggcatt[A/G] ttttggtaagtgactg 02 rs851356 2 p p24.1 NT5C1B|  19474112 1.05E− 1.13 0.252 0.230 G (SEQ ID NO: 0150) OSR1 05 tttaactgctcggccc[A/G] tgtacttgatcatgga 03 rs1871959 2 p p24.3 TRIB2|  13250740 2.61E− 1.45 0.025 0.017 A (SEQ ID NO: 0151) FAM84A 04 acatgttgcataggtt[A/C] tccctccattccctgt 03 rs4669910 2 p p24.3 TRIB2|  13289018 2.44E− 1.45 0.025 0.018 A (SEQ ID NO: 0152) FAM84A 04 atagctatagcaccgc[A/G] aattgccacatctgta 03 rs1813530 2 p p24.3 TRIB2|  13983167 1.46E− 1.35 0.043 0.032 G (SEQ ID NO: 0153) FAM84A 04 ttattgccattcttgt[A/G] gaagtaaggtggtatc 03 rs16860924 2 p p24.3 TRIB2|  14031175 3.36E− 1.33 0.042 0.031 G (SEQ ID NO: 0154) FAM84A 04 cataagtggtggaatc[A/G] ttgttcagaaacatta 03 rs4669907 2 p p24.3 TRIB2|  13279945 4.64E− 1.43 0.025 0.018 A (SEQ ID NO: 0155) FAM84A 04 tctagaaacttagtac[A/C] tcctgttgcattggta 02 rs1900854 2 p p24.3 TRIB2|  14422091 7.04E− 0.88 0.381 0.412 G (SEQ ID NO: 0156) FAM84A 05 tttacatacttttcct[A/G] ttgacttctccatatt 03 rs7608117 2 p p25.1 KCNF1|  11265972 1.99E− 1.12 0.503 0.473 A (SEQ ID NO: 0157) C2orf50 04 attccttctgggatct[A/C] ttaagggataaaaccg 02 rs1078589 2 p p25.2 SOX11|   5880342 1.01E− 1.13 0.056 0.050 A (SEQ ID NO: 0158) LOC150622 06 caccacattctctctc[A/G] tcagcttctcagacat 02 rs16864121 2 p p25.2 SOX11|   5892514 9.24E− 1.15 0.051 0.045 G (SEQ ID NO: 0159) LOC150622 07 aaaaattcctccatga[A/G] tcttacccagatggag 03 rs12714428 2 p p25.3 LOC    857713 2.00E− 1.11 0.341 0.318 A (SEQ ID NO: 0160) 100128185| 03 gggaggttcagcagcc[A/G] LOC391343 ccactgcgaggagtgg 01 rs17025744 2 q q11.2 TMEM131|  98636132 1.13E− 1.34 0.075 0.057 G (SEQ ID NO: 0161) VWA3B 06 ccagtgcttgaccctc[A/G] ccaacgaccgcactct 03 rs2302621 2 q q12.1 IL1RL2 102842124 8.49E− 1.11 0.411 0.385 C (SEQ ID NO: 0162) 04 ctcctgggaacttata[A/C] gagtaaaagtctgcag 02 rs2582974 2 q q12.1 LOC644265| 104578923 1.25E− 0.87 0.376 0.410 A (SEQ ID NO: 0163) LOC 05 gcaactaaaattaacc[A/G] 100287010 tacttctgattgtgtc 03 rs1159964 2 q q12.1 POU3F3| 105481442 3.06E− 1.10 0.428 0.405 G (SEQ ID NO: 0164) LOC 03 tcccatccagcttaag[A/G] 100128131 catttaaaatacaatt 03 rs732278 2 q q12.1 POU3F3| 105473698 3.91E− 1.10 0.446 0.424 A (SEQ ID NO: 0165) LOC 03 aaatgcctccttggtc[A/C] 100128131 gtttctcccgcgtttt 03 rs7602289 2 q q12.1 TMEM182| 103445960 2.81E− 0.88 0.256 0.281 G (SEQ ID NO: 0166) LOC644265 04 agcaatttatactggg[A/G] aaatatcagaaggtgt 03 rs2420589 2 q q14.1 DPP10 115722009 4.55E− 1.10 0.369 0.347 G (SEQ ID NO: 0167) 03 ggacagtaaataagaa[A/G] aaaagaactggagcaa 03 rs6745631 2 q q14.1 DPP10 115730919 4.01E− 1.10 0.295 0.275 C (SEQ ID NO: 0168) 03 ttcttatggctatttt[A/C] gtgtgtactcctactt 03 rs13429901 2 q q14.1 DPP10 116279799 2.42E− 1.11 0.128 0.117 A (SEQ ID NO: 0169) 02 taagaatcacagagag[A/G] cggagtaatcagaccg 03 rs10210316 2 q q14.1 DPP10 116298589 2.20E− 1.11 0.128 0.117 C (SEQ ID NO: 0170) 02 tattttgcatcccttc[A/C] ataaatacaaaaatgc 02 rs10206874 2 q q14.2 INHBB| 121160145 4.99E− 0.90 0.463 0.489 C (SEQ ID NO: 0171) LOC84931 05 actctgccacagacac[A/C] ttccctggagccctcc 03 rs7570552 2 q q14.2 MARCO| 119883331 7.92E− 0.88 0.315 0.343 G (SEQ ID NO: 0172) C1QL2 05 tgggagaaagggcttc[A/G] actgtggtttcagaca 03 rs9636365 2 q q14.2 MARCO| 119886918 7.31E− 0.88 0.316 0.344 A (SEQ ID NO: 0173) C1QL2 05 ctcttcctataaggat[A/G] cactgttggatctagg 03 rs12469732 2 q q14.3 LOC339760 127653376 2.71E− 1.17 0.105 0.092 A (SEQ ID NO: 0174) 03 gtcatgtaattttgat[A/G] accatcaaaaggattt 03 rs6728117 2 q q14.3 TSN| 123818496 7.09E− 0.88 0.120 0.134 C (SEQ ID NO: 0175) LOC 03 ttgatatgaagtgagc[A/C] 100288443 tgcataaatttcagtt 03 rs13011089 2 q q14.3 TSN| 123828854 2.21E− 0.90 0.120 0.132 A (SEQ ID NO: 0176) LOC 02 ttatgaagatctactt[A/C] 100288443 tattttgtcaatagta 03 rs309161 2 q q21.3 DARS 136688749 7.33E− 1.13 0.164 0.148 A (SEQ ID NO: 0177) 05 atttccaaattcttta[A/G] cccttgactttgctga 03 rs2322659 2 q q21.3 LCT 136555659 1.28E− 1.12 0.271 0.248 A (SEQ ID NO: 0178) 03 aagaatggagattaca[A/G] tgaggtgatgaagacg 02 rs309152 2 q q21.3 MCM6|DARS 136657252 1.81E− 1.13 0.161 0.144 G (SEQ ID NO: 0179) 05 gttggatctgtgaccc[A/G] tgctttctacagagaa 02 rs10187054 2 q q21.3 R3HDM1 136388473 1.04E− 1.31 0.176 0.140 C (SEQ ID NO: 0180) 05 gaggtcctttggggag[T/C] gataccattaatttgt 03 rs6739713 2 q q21.3 R3HDM1| 136488978 3.10E− 1.14 0.263 0.239 G (SEQ ID NO: 0181) UBXN4 04 tcactcaagaaaaaac[A/G] agaacagacaataata 03 rs9287442 2 q q21.3 UBXN4 136522710 2.02E− 1.12 0.248 0.227 A (SEQ ID NO: 0182) 03 atgtttcactaaagta[A/G] cagatgtgaaatagga 03 rs10188066 2 q q21.3 UBXN4 136539513 2.01E− 1.12 0.246 0.226 G (SEQ ID NO: 0183) 03 agctgtgtgtgatagc[A/G] tgtgcctatagtttca 02 rs1900741 2 q q21.3 ZRANB3 136002500 8.72E− 1.17 0.216 0.191 A (SEQ ID NO: 0184) 05 ttagaacatcacctat[A/G] ctgattactcccatgc 02 rs10221893 2 q q22.1 CXCR4| 137013606 2.10E− 1.15 0.446 0.412 G (SEQ ID NO: 0185) THSD7B 05 gagtgatttgcccatc[A/G] tgtaatggagactggt 02 rs6430612 2 q q22.1 CXCR4| 137006198 1.84E− 1.15 0.444 0.411 G (SEQ ID NO: 0186) THSD7B 05 ctcctccttaacatga[A/G] ttgagttcactttacc 03 rs6755074 2 q q22.2 KYNU 143683066 5.38E− 0.89 0.360 0.386 C (SEQ ID NO: 0187) 04 tgaaagagacggttac[A/C] tagtaccctgtttctg 03 rs11689575 2 q q22.3 LOC 145527778 1.09E− 1.19 0.095 0.081 A (SEQ ID NO: 0188) 100131409 03 caggatcccgtttagg[A/G] actttcaacacccttg 03 rs7603516 2 q q22.3 LOC 145504693 1.70E− 1.18 0.095 0.082 C (SEQ ID NO: 0189) 100131409 03 ctctgtgttgatgctt[A/C] cttccatattttgcac 03 rs11691685 2 q q22.3 LOC 145481827 7.74E− 1.21 0.087 0.074 G (SEQ ID NO: 0190) 100131409 04 atgagagaacatcact[A/G] tagataatttagactt 03 rs7560871 2 q q22.3 LOC 145616899 4.59E− 1.18 0.079 0.067 A (SEQ ID NO: 0191) 100131409| 03 aaacattttaaaatgt[A/G] PABPCP2 agtgggataaaacatg 03 rs4422110 2 q q22.3 LOC 146114898 9.30E− 0.89 0.448 0.478 G (SEQ ID NO: 0192) 100131409| 05 tcctgcctttgtataa[A/G] PABPCP2 catgctatttattcca 03 rs11690035 2 q q22.3 LOC 145603306 5.95E− 1.18 0.080 0.068 A (SEQ ID NO: 0193) 100131409| 03 atgatgtcttgtgaca[A/G] PABPCP2 ataataaagctatggg 02 rs12621827 2 q q23.2 LYPD6B 149981717 3.03E− 0.93 0.230 0.244 A (SEQ ID NO: 0194) 05 cagtcagtgctgtaac[A/G] tcacaaatcactaatc 01 rs1519761 2 q q23.3 RND3| 151633204 4.13E− 1.22 0.446 0.398 G (SEQ ID NO: 0195) RBM43 10 ttgtatatgagaaaaa[A/G] agaggcaattttttaa 03 rs12328269 2 q q23.3 RND3| 151774643 2.59E− 1.12 0.445 0.417 A (SEQ ID NO: 0196) RBM43 04 atgtctattgaagccc[A/G] cctttgacatttatga 01 rs7580162 2 q q23.3 RND3| 151655513 1.53E− 1.18 0.279 0.246 G (SEQ ID NO: 0197) RBM43 06 cttttttcttttccca[A/G] ttgcttcagtgatagc 01 rs6734792 2 q q23.3 RND3| 151624882 6.83E− 1.22 0.449 0.401 G (SEQ ID NO: 0198) RBM43 10 aaagcaaaaggtgaag[A/G] agttatttattatcca 01 rs9789673 2 q q23.3 RND3| 151627106 1.72E− 1.19 0.325 0.288 A (SEQ ID NO: 0199) RBM43 07 aataattttcagattt[A/C] tttgaacttactttct 01 rs1519768 2 q q23.3 RND3| 151648276 9.30E− 1.22 0.413 0.366 A (SEQ ID NO: 0200) RBM43 10 tcattgactttgaaaa[A/G] aattccagtcattatc 01 rs1519754 2 q q23.3 RND3| 151619693 1.29E− 1.21 0.446 0.400 C (SEQ ID NO: 0201) RBM43 09 tgaagagttagacaat[A/C] atttatttgagcatga 01 rs6728560 2 q q23.3 RND3| 151653870 3.30E− 1.18 0.278 0.246 A (SEQ ID NO: 0202) RBM43 06 acagaaagaaaatgcc[A/G] tcttgtagtaatccac 01 rs10515926 2 q q23.3 RND3| 151645865 6.00E− 1.20 0.415 0.370 A (SEQ ID NO: 0203) RBM43 09 cttgggaaggaacaca[A/G] tggattttccctggaa 02 rs12465911 2 q q23.3 RND3| 151785742 1.40E− 1.16 0.300 0.270 A (SEQ ID NO: 0204) RBM43 05 gcctccttgcctacaa[A/G] tcaaatagtaggattt 01 rs6757804 2 q q23.3 RND3| 151635832 3.85E− 1.22 0.446 0.398 G (SEQ ID NO: 0205) RBM43 10 cagtggggtgataggt[A/G] tgtcatggaaataata 03 rs12987780 2 q q24.3 CSRNP3 166470623 5.14E− 1.09 0.416 0.395 A (SEQ ID NO: 0206) 03 acaaaccttagcgagg[A/C] atagtggtgtgatgaa 03 rs1551825 2 q q24.3 KCNH7| 164340544 2.62E− 1.10 0.365 0.343 G (SEQ ID NO: 0207) FIGN 03 gaatatgaaatccacc[A/G] cactggctgtcaataa 03 rs11896706 2 q q24.3 SCN1A| 166993034 5.32E− 0.88 0.238 0.262 G (SEQ ID NO: 0208) SCN9A 04 agatagagatacatat[A/G] aagctactgctgtcct 03 rs7587026 2 q q24.3 SCN1A| 166978750 2.80E− 0.90 0.256 0.277 A (SEQ ID NO: 0209) SCN9A 03 aaaagcatactagcaa[A/C] atatattacaaagaac 03 rs7562413 2 q q24.3 STK39 168979569 3.66E− 1.10 0.344 0.323 A (SEQ ID NO: 0210) 03 cttaatatgatacaga[A/G] aagaacccaacatcac 03 rs2287618 2 q q31.1 ABCB11 169842809 5.79E− 1.10 0.326 0.306 A (SEQ ID NO: 0211) 03 cgaaattgactcaagc[A/G] ttttgtcttcacaggt 03 rs16864421 2 q q31.1 LOC375295| 177628237 3.38E− 1.27 0.060 0.048 A (SEQ ID NO: 0212) HNRNPA3 04 tgagagtcaaagaaga[A/G] gggaaaactccaggaa 02 exm244817 2 q q31.2 MIR548N 179315031 4.38E− Inf 0.056 0.010 G (SEQ ID NO: 0213) 62 gaatgtgaaagatctg[A/G] tgtgcaaatacacgtg 02 rs4563185 2 q q31.3 CWC22| 181684892 6.96E− 1.23 0.168 0.141 A (SEQ ID NO: 0214) LOC729009 04 ccaatcctttgggtta[A/G] ctgatttagtaggtaa 03 rs13034731 2 q q32.2 GULP1 189414364 5.29E− 0.89 0.356 0.382 A (SEQ ID NO: 0215) 04 gttttgatttctctgg[A/G] ataaatgtccaagtat 02 rs2709387 2 q q33.3 CREB1 208442095 9.76E− 0.87 0.170 0.191 A (SEQ ID NO: 0216) 03 tgctgattctttcaac[A/G] ctttagccagaatcat 02 rs1263628 2 q q33.3 KLF7 207977132 8.58E− 0.85 0.146 0.167 C (SEQ ID NO: 0217) 03 gaaatgattccataaa[C/G] cctgaatttatcttat 02 rs7582864 2 q q33.3 ZDBF2 207172627 3.60E− 1.13 0.425 0.396 A (SEQ ID NO: 0218) 05 ctgatgtttctgtcca[A/G] tctgtggctgatcaac 02 rs3732084 2 q q33.3 ZDBF2 207174316 4.57E− 1.13 0.417 0.388 A (SEQ ID NO: 0219) 05 ttggatccttccgaag[A/G] ctggcttctttgtgag 02 rs4673350 2 q q33.3 ZDBF2 207178872 4.33E− 1.12 0.426 0.398 G (SEQ ID NO: 0220) 05 tacaataaaaatctac[A/G] caaaatactgaacaag 02 rs1448902 2 q q33.3 ZDBF2 207178422 3.15E− 1.13 0.358 0.330 G (SEQ ID NO: 0221) 05 agagagaacagttcct[A/G] taattcaagtaattaa 03 rs2033645 2 q q34 ERBB4 212325378 2.59E− 1.23 0.058 0.048 G (SEQ ID NO: 0222) 03 tacagacagtttttgt[A/G] tatttcaacttgccat 03 rs1250258 2 q q35 FN1 216300185 3.96E− 1.13 0.285 0.261 G (SEQ ID NO: 0223) 04 ctgggatgataagacc[A/G] tgcattggaggacgag 03 rs12053317 2 q q35 WNT6 219733973 2.71E− 0.85 0.148 0.170 G (SEQ ID NO: 0224) 04 aaacacgtgtgtgtgc[A/G] cgtgcattctcatgcg 01 rs10184043 2 q q36.1 KCNE4| 224204870 2.30E− 1.20 0.283 0.248 A (SEQ ID NO: 0225) SCG2 07 tactgggtctgaagga[A/G] catgtggaggaggcag 01 rs10445738 2 q q36.1 KCNE4| 224186245 8.46E− 1.19 0.266 0.233 A (SEQ ID NO: 0226) SCG2 07 ccattcagcatttaca[A/G] tggtaccccaatagga 03 rs17190891 2 q q36.1 KCNE4| 224046645 4.07E− 1.18 0.138 0.120 A (SEQ ID NO: 0227) SCG2 04 ttgtccccaagttttc[A/G] tgtttagcacaatata 01 rs1400797 2 q q36.1 KCNE4| 224226772 4.31E− 1.23 0.293 0.252 A (SEQ ID NO: 0228) SCG2 09 attcaaactccaatat[A/G] gtcccaagtttaaaac 03 rs7580493 2 q q36.3 SPHKAP| 229427172 1.51E− 1.48 0.017 0.012 A (SEQ ID NO: 0229) PID1 03 tctacattgcttttct[A/G] tctgctatcacccctc 03 rs6431586 2 q q37.1 INPP5D| 234119635 4.44E− 1.19 0.115 0.099 A (SEQ ID NO: 0230) ATG16L1 04 tttgtgccccacggcg[A/G] ttctggacgcacctgt 03 rs10084197 2 q q37.1 NPPC| 232810183 2.86E− 1.11 0.308 0.286 G (SEQ ID NO: 0231) DIS3L2 03 cattaccaatagtaat[A/G] tcagaaatgaaacacc 03 rs838425 2 q q37.1 PTMA| 232597042 8.82E− 0.81 0.062 0.076 G (SEQ ID NO: 0232) PDE6D 04 gtatttcactccagga[A/G] tggaactgatagatct 02 exm284033 2 q q37.3 ANO7 242154318 6.11E− Inf 0.004 0.000 A (SEQ ID NO: 0233) 12 aggaggtcctcatccc[A/G] tgagtcccccactcct 03 rs7605254 2 q q37.3 ASB1| 239362938 9.60E− 0.91 0.274 0.293 A (SEQ ID NO: 0234) LOC 03 ctacccattttccttg[A/G] 100287050 agttacgtcccttggt 02 exm284661 2 q q37.3 BOK 242498984 8.95E− 3.49 0.021 0.008 G (SEQ ID NO: 0235) 16 gacaaggagctggtgg[C/G] ccaggccaaggcgctg 03 rs4073396 2 q q37.3 COPS8| 238111471 6.38E− 0.88 0.209 0.232 C (SEQ ID NO: 0236) COL6A3 04 cccacatctaagatac[A/C] caaaggtcagtgacgc 03 rs7585432 2 q q37.3 CXCR7| 237626734 1.22E− 1.16 0.132 0.115 C (SEQ ID NO: 0237) LOC93463 03 tgagcgtttaactcct[A/C] cctccccttactcaca 03 rs2067620 2 q q37.3 CXCR7| 237642373 8.83E− 1.17 0.124 0.108 G (SEQ ID NO: 0238) LOC93463 04 aggccttaaggacact[A/G] gtagactgaaggaggt 03 rs11679123 2 q q37.3 CXCR7| 237647424 7.96E− 1.17 0.124 0.108 A (SEQ ID NO: 0239) LOC93463 04 atccacatatccatcc[A/G] tccctctattctgaca 01 exm281099 2 q q37.3 HDAC4 240056067 7.45E− 125. 0.013 0.001 A (SEQ ID NO: 0240) 63 80 gctctcccttttcccc[A/G] gcacccacctcactcc 03 rs1796449 2 q q37.3 HDAC4| 240420675 2.21E− 0.89 0.423 0.452 A (SEQ ID NO: 0241) FLJ45964 04 ctgaactacacggagg[A/G] ggatgacacgggggct 03 rs1564974 2 q q37.3 HDAC4| 240436304 1.12E− 0.90 0.441 0.467 C (SEQ ID NO: 0242) FLJ45964 03 ggcaagccatcccgga[A/C] ggacgtcagatcctgg 03 rs1486323 2 q q37.3 HDAC4| 240417788 1.64E− 0.88 0.325 0.353 G (SEQ ID NO: 0243) FLJ45964 04 ctgggcacgtgcttca[A/G] taagaacagctgctca 03 rs4414678 2 q q37.3 KIF1A 241680633 4.58E− 1.12 0.372 0.346 A (SEQ ID NO: 0244) 04 tgtgtcggggggtgcg[A/C] ggagagggacgaggac 03 rs1845754 3 p p11.1 C3orf38|  88765697 4.79E− 1.10 0.358 0.337 A (SEQ ID NO: 0245) EPHA3 03 ataaatcccacttggt[A/C] atgatgaatgctcttt 03 rs1473624 3 p p12.2 GBE1|  83169976 1.76E− 1.16 0.193 0.171 G (SEQ ID NO: 0246) LOC 04 cttgaatttgtggatg[A/G] 100289598 tttgtgaaatgtaata 02 rs7618878 3 p p12.2 GBE1|  83089596 9.01E− 1.13 0.474 0.444 A (SEQ ID NO: 0247) LOC 07 ttattttatggacata[A/G] 100289598 tgtgtgggagcttgaa 03 rs1080728 3 p p12.2 GBE1|  83107505 7.42E− 0.89 0.239 0.260 A (SEQ ID NO: 0248) LOC 05 gaagcgcgcatgcaat[A/G] 100289598 gatccagggtgtatgc 03 rs1995065 3 p p12.2 GBE1|  82913445 6.05E− 1.11 0.407 0.383 A (SEQ ID NO: 0249) LOC 05 taacaaataggcagaa[A/G] 100289598 ttttgagcaacattaa 02 rs11127807 3 p p12.2 GBE1|  83130081 3.10E− 1.14 0.474 0.443 G (SEQ ID NO: 0250) LOC 07 atattgtactttgtat[A/G] 100289598 cagaatttcaacttgg 03 rs6806032 3 p p12.2 GBE1|  83132865 7.90E− 0.89 0.236 0.258 G (SEQ ID NO: 0251) LOC 05 tttctttatctagtgg[A/G] 100289598 cacttttaggtcgatt 03 rs2121783 3 p p13 FOXP1  71174475 6.22E− 0.90 0.404 0.431 G (SEQ ID NO: 0252) 04 tttttgtgtgtatgtc[A/G] ttcttgaatacagtga 03 rs9862251 3 p p14.2 PTPRG  61587570 2.48E− 1.12 0.120 0.109 G (SEQ ID NO: 0253) 02 aaggaggtaaagttaa[A/G] agttaggagcagaggg 01 exm321427 3 p p21.1 SEMA3G  52475886 1.55E− Inf 0.004 0.000 A (SEQ ID NO: 0254) 20 tgagggcaccgccccc[A/G] gccactttccacactg 03 rs375544 3 p p21.2 MAPKAPK3  50657826 1.28E− 1.19 0.151 0.130 G (SEQ ID NO: 0255) 04 ctgcctccctggtgat[A/G] tactccaggttaacca 01 rs4688718 3 p p21.31 CACNA2D2  50522063 4.92E− 1.16 0.423 0.387 A (SEQ ID NO: 0256) 06 tcacctgctccgtgaa[A/G] acctccttgcccctcc 02 rs2236951 3 p p21.31 CACNA2D2  50421081 2.54E− 1.17 0.223 0.197 G (SEQ ID NO: 0257) 05 gccaggagctggggat[A/G] taaggaagggggatgt 02 exm311992 3 p p21.31 COL7A1  48623625 4.98E− 4.22 0.009 0.002 A (SEQ ID NO: 0258) 08 ccagagcagctgcgtc[A/G] cttggcgccgggtatg 02 rs2233474 3 p p21.31 TUSC4|  50388607 1.37E− 1.21 0.160 0.136 A (SEQ ID NO: 0259) CYB561D2 05 ttacatggctttgcgc[A/C] tcctacctggaaggcg 02 exm304730 3 p p22.1 CYP8B1  42916596 2.38E− Inf 0.003 0.000 G (SEQ ID NO: 0260) 09 cagcgtctctttcaca[A/G] gatgctctccgtgagc 03 rs5029848 3 p p22.1 LOC  42110843 1.99E− 0.91 0.400 0.424 C (SEQ ID NO: 0261) 100287063 03 tgcaccatccgaccca[A/C] ccataacttttctttt 03 rs7644110 3 p p22.1 LOC  42115488 1.85E− 0.91 0.401 0.425 G (SEQ ID NO: 0262) 100287063 03 gagttcctttgcccct[A/G] ttacgacaagagggtt 03 rs1995137 3 p p22.1 LOC  42131415 1.60E− 0.90 0.405 0.429 A (SEQ ID NO: 0263) 100287063| 03 gtgtatcaattgtgtc[A/G] TRAK1 atttgtgcagtgagta 03 rs10514703 3 p p22.1 LOC729505|  40901256 7.31E− 0.80 0.037 0.046 A (SEQ ID NO: 0264) CTNNB1 03 aaacaatgaagccaag[A/G] acagaagtgactggac 03 rs6798614 3 p p22.1 LOC729505|  40930857 7.30E− 0.80 0.037 0.045 A (SEQ ID NO: 0265) CTNNB1 03 gtttttatgtcagctc[A/G] acctttgcttttaagt 02 exm302831 3 p p22.1 MYRIP  40085729 1.94E− 34.6 0.004 0.000 G (SEQ ID NO: 0266) 08 4 taccagaagcacgaaa[A/G] ggcctgggtctgctgc 03 rs4293737 3 p p22.3 CMTM8  32373530 1.28E− 1.10 0.209 0.193 A (SEQ ID NO: 0267) 02 tcttttgaccacacgc[A/G] cacacacacacacaca 03 rs11713777 3 p p22.3 GPD1L|  32245557 3.18E− 1.21 0.101 0.085 G (SEQ ID NO: 0268) LOC 04 atggatatgcagttag[A/G] 100129194 aaaatgagtcatcact 03 rs12493245 3 p p24.1 EOMES|  27797810 2.08E− 1.11 0.370 0.347 A (SEQ ID NO: 0269) CMC1 03 gtcgtaacttaaaatc[A/G] tattcaaagctgtgat 03 rs4343572 3 p p24.2 LOC644990|  24732019 1.36E− 0.92 0.361 0.379 A (SEQ ID NO: 0270) LOC 02 ttcataattctacttt[A/G] 100130354 ctggaatcagctgaga 03 rs4600774 3 p p24.2 LOC644990|  24731037 2.65E− 0.90 0.297 0.319 A (SEQ ID NO: 0271) LOC 03 aagcaaagcaagcaaa[A/G] 100130354 catcatctgtatttat 03 rs7610222 3 p p24.2 THRB  24357286 6.07E− 0.91 0.253 0.272 A (SEQ ID NO: 0272) 03 attagtggagtgaact[A/G] cttctccctgcaatta 01 exm2265568 3 p p24.3 VENTXP7|  23242050 1.34E− 2.49 0.004 0.000 G (SEQ ID NO: 0273) UBE2E2 08 aactaactgtggctct[A/G] cttactcacgaagttg 03 rs6442476 3 p p25.1 C3orf20  14812460 2.43E− 1.10 0.486 0.462 G (SEQ ID NO: 0274) 03 tgtgaggtgtggcaca[A/G] aggtaaggaatagcca 02 rs7651825 3 p p25.1 C3orf20  14812118 4.03E− 0.90 0.418 0.444 A (SEQ ID NO: 0275) 05 cccagagctacctcaa[A/G] ccccctccccaagcca 03 rs2697149 3 p p25.3 SLC6A1  11036480 6.59E− 1.11 0.240 0.222 C (SEQ ID NO: 0276) 03 gggtaaagatgaggca[A/C] aatcaagtccatcgaa 03 rs6792001 3 p p26.1 EDEM1|   6106251 2.02E− 1.16 0.183 0.161 A (SEQ ID NO: 0277) GRM7 04 gatgcaattagagata[A/G] gctttaggaagatctt 02 exm285495 3 p p26.3 CHL1    391100 7.65E− 44.1 0.005 0.000 A (SEQ ID NO: 0278) 11 2 accaaaggggagagaa[A/G] caaaagaaaattatgg 03 rs2044602 3 p p26.3 CNTN4   2315400 3.66E− 0.91 0.416 0.438 A (SEQ ID NO: 0279) 03 attttcctcttaatgc[A/G] gtactaatatatgttg 03 rs16840752 3 q q12.1 DCBLD2|  98924050 6.69E− 1.15 0.046 0.040 A (SEQ ID NO: 0280) COL8A1 02 gacttcacatagtgcc[A/G] cctagttcttccaatg 03 rs1848252 3 q q12.2 ABI3BP| 100818827 5.34E− 1.15 0.210 0.187 G (SEQ ID NO: 0281) IMPG2 05 cctctacccccaggct[A/G] aaaaggcctgacacaa 02 rs16843225 3 q q12.2 ABI3BP| 100801257 1.13E− 0.81 0.122 0.146 C (SEQ ID NO: 0282) IMPG2 05 ctgtgtagctatttga[A/C] gatatgctggcctgta 02 rs2036650 3 q q12.2 ABI3BP| 100834729 2.07E− 1.17 0.201 0.177 C (SEQ ID NO: 0283) IMPG2 05 aaaaaaaaaaataagt[A/C] ctcttaaagctagcac 02 rs650567 3 q q12.3 NFKBIZ| 101594402 4.53E− 0.88 0.397 0.428 A (SEQ ID NO: 0284) LOC152225 05 ttctaaaaaagcaact[A/C] ctcatgagaagctgta 02 rs641432 3 q q12.3 NFKBIZ| 101587566 2.88E− 0.88 0.425 0.458 A (SEQ ID NO: 0285) LOC152225 05 gttgagtccttctcag[A/G] cttggaatctctaaga 03 rs16844076 3 q q12.3 PCNP 101296067 1.06E− 1.32 0.052 0.040 G (SEQ ID NO: 0286) 04 tctcctccctttggtt[A/G] aatctttgtagctgtt 02 rs2303476 3 q q12.3 RG9MTD1 101280993 9.87E− 1.32 0.052 0.040 G (SEQ ID NO: 0287) 05 ttgtttcaggtactgt[A/G] ctagttatagtttatt 03 rs6793744 3 q q13.11 CBLB| 105897816 5.72E− 1.11 0.057 0.052 G (SEQ ID NO: 0288) LOC344593 05 ccagccaggatattca[A/G] aggaccgaaccctctt 03 rs6774644 3 q q13.12 CBLB| 106379000 5.37E− 0.86 0.144 0.164 G (SEQ ID NO: 0289) LOC344593 04 ttgagtgtgaaagaat[A/G] taacagtaaaaataaa 03 rs12633892 3 q q13.12 CBLB| 106380005 9.96E− 0.86 0.145 0.164 G (SEQ ID NO: 0290) LOC344593 04 ctacatgagaaacctg[A/G] gagctatcttcaaatc 03 rs7613153 3 q q13.12 CBLB| 106380604 1.03E− 0.86 0.144 0.163 A (SEQ ID NO: 0291) LOC344593 03 taatgctagccttcct[A/G] gagtctagtatttcag 03 rs7617430 3 q q13.12 CBLB| 106392429 4.80E− 0.85 0.122 0.141 A (SEQ ID NO: 0292) LOC344593 04 ctagcacgttttattg[A/G] ccatcattcttttcat 02 exm337642 3 q q13.2 CCDC80 112357336 2.19E− 5.62 0.015 0.003 A (SEQ ID NO: 0293) 15 gggtctcggtggccat[A/G] ttcccgcctgtccatg 03 rs16824243 3 q q13.31 LSAMP 115603783 5.66E− 0.83 0.091 0.108 G (SEQ ID NO: 0294) 04 ttcaaaggtcaggcaa[A/G] ttgattttgaaaagaa 03 rs1731596 3 q q13.31 LSAMP 116131208 2.13E− 1.15 0.218 0.195 C (SEQ ID NO: 0295) 04 ctgcatagtgagactg[A/C] atgtttttcaggagtt 03 rs9838534 3 q q13.31 LSAMP 116113609 2.48E− 1.15 0.218 0.195 A (SEQ ID NO: 0296) 04 tgtggaagaaaaacac[A/G] tattagttcaataaat 03 rs6782605 3 q q13.31 LSAMP 116047619 1.55E− 1.19 0.094 0.081 A (SEQ ID NO: 0297) 03 tgatgaatgataatta[A/G] cttttcctctagagca 02 rs1265646 3 q q21.2 ITGB5 124592700 6.86E− 0.90 0.368 0.394 A (SEQ ID NO: 0298) 06 tacacttagtctatcc[A/G] aaatgacaaaaatagt 02 exm347865 3 q q21.3 KBTBD12 127642561 1.95E− 5.97 0.025 0.007 C (SEQ ID NO: 0299) 54 ttgagcttttgaagca[A/C] gtcagattggaacttg 03 rs4683547 3 q q23 SPSB4 140801587 7.54E− 0.87 0.102 0.116 A (SEQ ID NO: 0300) 03 aaactgaggctgtgaa[A/C] ggctgaaaggtttcag 03 rs12489920 3 q q26.1 OTOL1| 162391801 1.21E− 1.12 0.284 0.262 A (SEQ ID NO: 0301) LOC730129 03 gaaccagagcataagc[A/G] gcattgttcatatggt 02 rs7643215 3 q q26.1 ZBBX 167023279 2.99E− 0.85 0.221 0.249 G (SEQ ID NO: 0302) 05 attaatgttctctccc[A/G] tatgagtcactcttca 02 rs9881097 3 q q26.31 GHSR| 172185376 5.44E− 1.13 0.496 0.465 A (SEQ ID NO: 0303) TNFSF10 03 aggatgaagcttaact[A/G] aggaaggtagaaccaa 03 rs7632772 3 q q26.32 NAALADL2| 176103902 7.34E− 1.15 0.101 0.089 G (SEQ ID NO: 0304) TBL1XR1 03 caaaagcctgaggaag[A/G] gtgaaaagaacaaagc 03 rs1106387 3 q q26.32 TBL1XR1| 177490268 7.34E− 1.12 0.293 0.271 A (SEQ ID NO: 0305) KCNMB2 05 ttggaagagaaaggaa[A/G] aaaattttatgtggct 03 rs1106388 3 q q26.32 TBL1XR1| 177490311 8.87E− 1.12 0.293 0.271 G (SEQ ID NO: 0306) KCNMB2 05 cagcccagaaaatatt[A/G] aaaagataatgagcaa 02 rs6443448 3 q q26.32 TBL1XR1| 177074926 2.16E− 0.91 0.393 0.416 G (SEQ ID NO: 0307) KCNMB2 05 aaagtaacatcaggga[A/G] gtctggaaataaaatg 02 exm372681 3 q q28 CCDC50 191098660 1.05E− 19.0 0.012 0.001 G (SEQ ID NO: 0308) 21 1 gaaaagaaagcttaca[A/G] aaaagccaaggagcgg 03 rs890348 3 q q28 LPP 188241949 5.79E− 1.08 0.168 0.158 G (SEQ ID NO: 0309) 05 ggtcttgccatctctc[A/G] cacacatgcataccta 02 exm376611 3 q q29 C3orf43 196236401 6.01E− Inf 0.012 0.000 A (SEQ ID NO: 0310) 31 actcactggagtgccc[A/G] aactgctgtccacatc 02 rs6444670 3 q q29 C3orf59 192599336 8.91E− 0.86 0.360 0.394 C (SEQ ID NO: 0311) 06 agaaaactgtactgac[A/C] gctacgaagtttgagc 02 rs6799698 3 q q29 LRRC15| 194105437 5.36E− 1.21 0.126 0.106 A (SEQ ID NO: 0312) GP5 03 cccaagccaactcaac[A/G] cctgcagatggctctt 03 rs10021613 4 p p13 APBB2  41201819 8.45E− 1.17 0.135 0.118 A (SEQ ID NO: 0313) 04 gcttcactgttcttcc[A/G] gtgtctagtggcaaac 03 rs7683746 4 p p13 APBB2  41203125 9.13E− 1.17 0.136 0.119 A (SEQ ID NO: 0314) 04 gacagttgccttatac[A/G] gagggctcattaaaca 02 rs1373475 4 p p14 FLJ16686|  36931424 7.58E− 1.18 0.171 0.148 A (SEQ ID NO: 0315) KIAA1239 05 ggaagagtgaagaaga[A/G] gagaagatgcccaagc 02 rs1020808 4 p p14 FLJ16686|  36949073 1.88E− 1.20 0.177 0.153 A (SEQ ID NO: 0316) KIAA1239 05 tagtgaccttataaga[A/G] gagatgtcagaaaatt 03 rs4832890 4 p p14 KIAA1239  37264627 1.41E− 0.92 0.360 0.379 A (SEQ ID NO: 0317) 02 catcatgaagttcatg[A/G] agccgagaccaccagt 03 rs10001618 4 p p14 KIAA1239  37340671 1.20E− 1.28 0.027 0.021 G (SEQ ID NO: 0318) 02 gaaatgatgtgtgact[A/G] aacaaagagacatgca 02 rs3796533 4 p p14 KLF3  38692806 9.85E− 1.20 0.181 0.155 A (SEQ ID NO: 0319) 06 ggcaaagtgattacct[A/G] agacattagataactc 01 rs17582575 4 p p14 KLF3|  38703734 2.66E− 1.21 0.193 0.165 A (SEQ ID NO: 0320) TLR10 06 cttcccacatgactta[A/C] tttcacaggttggaga 02 rs6838865 4 p p14 KLF3|  38745883 2.27E− 1.22 0.115 0.096 A (SEQ ID NO: 0321) TLR10 05 agactccttacctcta[A/C] tgaaatcatcccaaac 02 rs12233656 4 p p14 KLF3|  38737018 4.07E− 1.22 0.096 0.080 G (SEQ ID NO: 0322) TLR10 05 attgctccaataatag[A/G] cgtgtatttctcatgt 03 rs6849452 4 p p15.1 PCDH7|  31216675 1.12E− 1.14 0.311 0.283 A (SEQ ID NO: 0323) ARAP2 04 tgcaatatttcctctc[A/G] ctccttatgtctactc 03 rs7659139 4 p p15.2 KCNIP4|  22297899 2.66E− 0.84 0.122 0.142 G (SEQ ID NO: 0324) GPR125 04 taggcctcagcccccc[A/G] tttaaacagagggtaa 03 rs6448143 4 p p15.2 KCNIP4|  22303196 8.02E− 0.86 0.130 0.148 G (SEQ ID NO: 0325) GPR125 04 cacactgttagagtgt[A/G] tttgagcatgtgggag 02 rs7697101 4 p p15.2 KCNIP4|  22174771 5.99E− 0.86 0.478 0.516 C (SEQ ID NO: 0326) LOC 04 tcctgcataggtgtcc[T/C] 100505912 tcttaaaaaataattg 02 exm393187 4 p p15.2 SEL1L3  25834624 9.17E− 8.41 0.005 0.001 A (SEQ ID NO: 0327) 08 gatatctcttttaacg[A/G] aggccaggtatctgta 02 rs11721812 4 p p15.2 SLC34A2|  25730546 1.49E− 1.23 0.121 0.101 A (SEQ ID NO: 0328) KIAA0746 05 aaggtctccttggcca[A/G] taagagtctgttcagt 03 rs210777 4 p p15.2 STIM2|  27432523 1.44E− 1.14 0.188 0.170 A (SEQ ID NO: 0329) PCDH7 03 agatttttatgtgcct[A/G] atgatagtctcaaaat 03 rs7693245 4 p p15.31 LCORL|  18321896 2.13E− 1.10 0.471 0.447 G (SEQ ID NO: 0330) SLIT2 03 ccccactacactcata[A/G] gcagctgatttgcaca 03 rs4140904 4 p p15.31 LCORL|  18315992 2.96E− 1.08 0.253 0.238 G (SEQ ID NO: 0331) SLIT2 02 tgaagatagaatggca[A/G] ataccctatcctatcc 03 rs3846386 4 p p15.33 LOC391636|  14102069 3.29E− 1.11 0.269 0.248 G (SEQ ID NO: 0332) LOC441009 03 gattctatccgtctgc[A/G] accccccacccttgca 03 rs4689003 4 p p16.1 PPP2R2C   6428296 9.71E− 1.14 0.182 0.163 G (SEQ ID NO: 0333) 05 ggcaattgtggtcctt[A/G] tatttcagacacaagc 02 exm379901 4 p p16.3 DGKQ    961122 4.35E− Inf 0.004 0.000 A (SEQ ID NO: 0334) 11 gcgggcccaccacatc[A/C] ccgaggaccctggcca 02 rs4865455 4 p p16.3 FAM53A   1653352 3.18E− 1.15 0.355 0.324 C (SEQ ID NO: 0335) 03 aaggcctgaggcagaa[C/T] aaccggggtcaagagg 03 rs12331507 4 q q12 KDR|  56011889 1.83E− 0.88 0.304 0.332 A (SEQ ID NO: 0336) SRD5A3 04 accatcagcctctcac[A/G] atttttgagtagttcc 02 rs12505096 4 q q12 KDR|  56006102 4.20E− 0.87 0.269 0.298 A (SEQ ID NO: 0337) SRD5A3 05 tggggctgaagaatac[A/C] tttctggtgtgactca 02 exm400714 4 q q12 KIAA1211  57180701 5.39E− 7.33 0.012 0.002 G (SEQ ID NO: 0338) 15 caggctggaggagcgg[A/G] ggcggcaggaggagga 02 rs6554072 4 q q12 SCFD2  54079547 2.04E− 0.84 0.345 0.384 G (SEQ ID NO: 0339) 04 aatgaatcaagtcaga[C/G] gcatttttttctactc 02 rs11724057 4 q q13.1 LPHN3  62686490 7.24E− 1.23 0.135 0.113 A (SEQ ID NO: 0340) 06 ttgtaaataagtacat[A/G] agagttcttagcagga 03 rs7683391 4 q q13.1 LPHN3  62676117 2.73E− 1.17 0.154 0.134 G (SEQ ID NO: 0341) 04 tctcatcctaaaatgt[A/G] gattctggaatataag 03 rs1901223 4 q q13.1 LPHN3  62660731 3.78E− 1.12 0.434 0.406 A (SEQ ID NO: 0342) 04 taaaagcactttacat[A/G] aataattttatgtcag 03 rs6534447 4 q q13.3 DKFZP564  76005892 1.62E− 0.78 0.062 0.078 A (SEQ ID NO: 0343) O0823 04 tgtcacttgttaatga[A/C] |RCHY1 cttccaatcttctaag 02 exm407053 4 q q21.1 ART3  76956246 6.81E− 13.7 0.004 0.000 G (SEQ ID NO: 0344) 08 5 aaagaaaataaaggac[A/G] acgatgcctaaatccc 03 rs953534 4 q q21.22 SCD5  83617849 1.47E− 1.11 0.332 0.309 A (SEQ ID NO: 0345) 03 cagctgggggagaaat[A/C] atccaaaatgcaatat 03 rs2869362 4 q q21.23 ARHGAP24  86591202 8.95E− 1.16 0.083 0.072 A (SEQ ID NO: 0346) 03 atttttattcagttgg[A/G] atggggtggctgcaaa 03 rs1482090 4 q q21.23 ARHGAP24  86523580 3.91E− 1.18 0.086 0.074 G (SEQ ID NO: 0347) 03 ttgtgctcaggcaagt[A/G] tgttgattggataaat 03 rs1161262 4 q q21.23 ARHGAP24  86508815 6.41E− 1.19 0.083 0.070 G (SEQ ID NO: 0348) 05 tcatttattaaaacac[A/G] gcatgattagaccact 03 rs7697141 4 q q22.1 KIAA1680  92457618 2.43E− 1.26 0.067 0.054 G (SEQ ID NO: 0349) 04 gtctctacctttttct[A/G] ccctgctttgctccct 03 rs6847228 4 q q22.1 TIGD2  90155694 2.76E− 1.32 0.045 0.034 A (SEQ ID NO: 0350) GPRIN3 04 agggagtggaaagaaa[A/G] agtgctgcaatttttt 03 rs17020045 4 q q22.2 GRID2  93892487 2.03E− 0.93 0.463 0.482 G (SEQ ID NO: 0351) 02 tagtacagatttttat[A/G] ttgcaatcaaatccta 03 rs1354296 4 q q22.2 GRID2  94075263 7.45E− 1.09 0.457 0.436 A (SEQ ID NO: 0352) 03 tgttaccaactgatta[A/G] ggtacaagttttagga 03 rs11727464 4 q q22.2 GRID2  94324475 2.55E− 0.89 0.399 0.427 A (SEQ ID NO: 0353) 04 ccagaagtgaaactgt[A/G] ggaactgtgttcttaa 02 rs11097364 4 q q22.2 GRID2  94367364 4.23E− 0.89 0.453 0.482 A (SEQ ID NO: 0354) 05 taggactcattcacat[A/G] gtgatccagggttcct 03 rs2174558 4 q q25 ANK2 113927365 6.72E− 1.15 0.106 0.094 A (SEQ ID NO: 0355) 03 gttgtttgggctatcc[A/G] tcttctcaactgttta 03 rs378405 4 q q25 DKK2| 108000247 1.62E− 1.13 0.192 0.173 A (SEQ ID NO: 0356) LOC 03 atttagtatataataa[A/C] 100288317 agtaacactacagcac 03 rs425273 4 q q25 DKK2| 108016162 2.58E− 1.13 0.199 0.180 G (SEQ ID NO: 0357) LOC 03 gggccccttccttgct[A/G] 100288317 acctgcagtagcatgt 03 rs852269 4 q q25 LEF1| 109236454 1.95E− 0.90 0.126 0.139 G (SEQ ID NO: 0358) LOC285456 02 caaagggaagtatacc[A/G] ctaaataaggaaggca 03 rs220634 4 q q25 LEF1| 109235238 1.88E− 0.89 0.124 0.137 A (SEQ ID NO: 0359) LOC285456 02 cgtggctccaggactg[A/G] tctcagcctttgcata 03 rs1476569 4 q q26 CAMK2D| 114698696 3.28E− 1.11 0.305 0.284 G (SEQ ID NO: 0360) ARSJ 03 tatctcagattcatga[A/G] atggtaacttctatgt 03 rs4629529 4 q q26 NDST4| 117572163 1.10E− 0.88 0.221 0.243 C (SEQ ID NO: 0361) TRAM1L1 03 tctcaccaaggtcacc[A/C] gtgacttctagctgag 02 rs1503535 4 q q27 LOC730456| 120898509 9.10E− 1.13 0.396 0.367 G (SEQ ID NO: 0362) MAD2L1 05 ctaaagagtactgtaa[A/G] gttaaagggatcatgt 03 rs7684836 4 q q27 QRFPR| 122526728 3.27E− 1.17 0.096 0.083 A (SEQ ID NO: 0363) ANXA5 03 acaatgacttaacaat[A/C] cctttcctttctgatt 03 rs10857108 4 q q28.1 FAT4| 126780071 2.20E− 1.14 0.174 0.157 A (SEQ ID NO: 0364) LOC729424 03 taaccttgatcactgg[A/G] ctgaagtagtgtttgt 03 rs1911014 4 q q28.1 FAT4| 126774098 7.02E− 1.12 0.172 0.157 A (SEQ ID NO: 0365) LOC729424 03 cttaagaaggatacac[A/G] aaatatgtatgtatat 03 rs958632 4 q q28.3 PABPC4L| 136572585 1.39E− 1.18 0.109 0.094 A (SEQ ID NO: 0366) LOC 03 ccctggcaaccaaaga[A/G] 100289626 ggagcttttacaccag 02 rs2035469 4 q q28.3 PABPC4L| 136288768 1.19E− 1.16 0.433 0.398 G (SEQ ID NO: 0367) LOC 03 ctgccttctcagagtt[A/G] 100289626 aacctgacataattta 03 rs13435856 4 q q31.1 SLC7A11| 139535299 3.61E− 1.36 0.035 0.026 A (SEQ ID NO: 0368) CCRN4L 04 gcaaatgagaataatc[A/G] ttttttgtcttttcca 01 rs4835378 4 q q31.22 LOC 148040980 3.46E− 1.20 0.216 0.188 C (SEQ ID NO: 0369) 100287219| 06 ggaatgaacttctaaa[A/C] EDNRA tgctgtaatctcttga 02 rs3749574 4 q q31.3 LRBA 151207127 1.98E− 0.86 0.277 0.307 A (SEQ ID NO: 0370) 05 tgaggtcacatgtgct[A/G] cggtgtgtgcggagct 03 rs9995821 4 q q31.3 SFRP2| 154828366 4.02−E 1.15 0.211 0.189 G (SEQ ID NO: 0371) DCHS2 04 tagtcaaattcattca[A/G] tgtggctcagatatga 02 rs11941518 4 q q32.1 CTSO| 156950378 6.42E− 1.22 0.146 0.123 G (SEQ ID NO: 0372) PDGFC 06 atgtgaacattttttt[A/G] gacaagtttattgcta 03 rs6536518 4 q q32.1 RAPGEF2| 161308423 3.53E− 1.12 0.463 0.435 A (SEQ ID NO: 0373) FSTL5 04 aacacagccaacatca[A/G] ttaagcctaatttaca 02 rs1898871 4 q q32.1 RAPGEF2| 161402299 2.83E− 1.11 0.381 0.358 A (SEQ ID NO: 0374) FSTL5 06 ggaaaagtggaatgcc[A/G] agaacagaaactaaga 02 rs1371251 4 q q32.1 RAPGEF2| 161381482 1.70E− 1.13 0.458 0.428 A (SEQ ID NO: 0375) FSTL5 05 ctctctagagtttact[A/G] tcatctggcattcatg 02 rs6827968 4 q q32.1 RAPGEF2| 161399652 1.96E− 1.12 0.393 0.366 A (SEQ ID NO: 0376) FSTL5 06 ctacatggaaaattga[A/C] gtagcaaggtaggtca 02 rs13151634 4 q q32.1 RAPGEF2| 161411394 2.21E− 1.14 0.480 0.448 A (SEQ ID NO: 0377) FSTL5 07 agcctgtctcctctgg[A/G] agtcttatctctcagt 02 rs4690982 4 q q32.1 RAPGEF2| 161428827 2.06E− 1.10 0.394 0.371 A (SEQ ID NO: 0378) FSTL5 05 ttccatatcctcgtcc[A/G] caattagtacgcacag 02 rs4690983 4 q q32.1 RAPGEF2| 161429238 1.58E− 1.10 0.393 0.370 A (SEQ ID NO: 0379) FSTL5 05 catgtttactatctct[A/G] taggtttgcctttttg 03 rs1946867 4 q q32.1 RAPGEF2| 161307463 1.06E− 0.88 0.446 0.476 A (SEQ ID NO: 0380) FSTL5 04 taccaaattgtatggt[A/G] tcagtgatggcagcag 01 rs4525928 4 q q32.1 RAPGEF2| 161421752 8.63E− 1.15 0.489 0.454 C (SEQ ID NO: 0381) FSTL5 08 cagaactgaaataatt[A/C] tccataggatccttag 03 rs17039615 4 q q32.1 RAPGEF2| 161406478 8.21E− 1.14 0.204 0.183 A (SEQ ID NO: 0382) FSTL5 04 ttttaatgaagcccct[A/G] taggctagttgtcaag 03 rs9996901 4 q q32.2 FSTL5 162482595 7.20E− 1.19 0.112 0.096 A (SEQ ID NO: 0383) 04 catctcaaaccatgca[A/G] ttcctggaaatcacta 03 rs6536728 4 q q32.2 NPY5R| 164333380 3.09E− 1.14 0.155 0.139 G (SEQ ID NO: 0384) TKTL2 03 tgcaaggaaaccattt[A/G] ccagcctcctgcaatt 03 rs10024430 4 q q32.2 NPY5R| 164295108 1.44E− 1.33 0.033 0.025 G (SEQ ID NO: 0385) TKTL2 03 ctgaaaataagttccc[A/G] catatatattgtagaa 02 rs1534578 4 q q32.3 ANP32C| 165514302 2.48E− 1.16 0.252 0.226 G (SEQ ID NO: 0386) LOC 05 tgatgctataattcct[A/G] 100131276 gattttgtttgatttc 03 rs1459509 4 q q32.3 CPE|TLL1 166602111 1.15E− 1.16 0.076 0.066 A (SEQ ID NO: 0387) 02 ctagagaagatgaagg[A/G] atgtgcattccaggca 03 rs7695819 4 q q33 AADAT| 171808256 5.63E− 1.09 0.232 0.217 A (SEQ ID NO: 0388) LOC441052 05 tgctcaagagcagacc[A/G] gatgagccacacatgg 02 rs1432083 4 q q33 AADAT| 171813412 1.91E− 1.14 0.345 0.317 G (SEQ ID NO: 0389) LOC441052 05 agggatcaattcttac[A/G] ataaaattttaaaacc 03 rs2584393 4 q q34.3 LOC 180591910 1.07E− 1.15 0.176 0.157 A (SEQ ID NO: 0390) 100288304| 03 tgaaactgagtaaacc[A/G] LOC ttaagaatgaattatt 100288373 03 rs6852438 4 q q34.3 LOC 182061996 3.50E− 1.14 0.242 0.219 G (SEQ ID NO: 0391) 100288304| 04 ctgcataagccctggc[A/G] LOC tgctaccacagcccaa 100288373 03 rs6837023 4 q q34.3 LOC 180330521 2.38E− 1.23 0.088 0.073 A (SEQ ID NO: 0392) 100288304| 04 gtgtgtcccatgtggc[A/G] LOC agagctcaaacaaggc 100288373 03 rs4861466 4 q q34.3 LOC 182064722 2.53E− 1.10 0.470 0.446 G (SEQ ID NO: 0393) 100288304| 03 atctaagttaaggtag[A/G] LOC aatgatgaggtcaaaa 100288373 03 rs4400034 4 q q35.1 C4orf41 184586738 6.03E− 1.14 0.135 0.121 A (SEQ ID NO: 0394) 03 acttcatggtgatcca[A/C] tgtctacctccagcaa 03 rs12108497 4 q q35.1 CCDC111 185571557 6.43E− 1.12 0.316 0.291 A (SEQ ID NO: 0395) 05 gtgactataaaagatg[A/G] ggccttcggcagctcc 03 rs6850330 4 q q35.1 CDKN2AIP| 184415303 2.55E− 1.26 0.068 0.055 C (SEQ ID NO: 0396) ING2 04 atattaatacgtggct[A/C] agattaatgacagcaa 02 rs4861551 4 q q35.1 CLDN24| 184362068 6.81E− 1.15 0.280 0.253 G (SEQ ID NO: 0397) LOC 05 ggcaactcacagaaaa[A/G] 100131811 gagagtttgaggatct 03 rs766908 4 q q35.1 IRF2| 185468885 4.92E− 1.15 0.120 0.107 G (SEQ ID NO: 0398) CASP3 03 aaacaatgctgaggag[A/G] ctttatctttacagtt 02 rs11939575 4 q q35.2 FAT1 187627792 3.04E− 0.85 0.187 0.214 A (SEQ ID NO: 0399) 05 tcatgatgaggacgcc[A/G] gaagagatggggagat 02 rs13123522 4 q q35.2 FAT1 187627160 2.65E− 0.85 0.188 0.215 G (SEQ ID NO: 0400) 05 tggcatgctgaactga[A/G] aagacctggcttggaa 03 rs327080 4 q q35.2 FAT1 187593959 4.71E− 0.89 0.305 0.331 G (SEQ ID NO: 0401) 04 tccctccaattgaagg[A/G] caggcagggactccaa 03 rs2279551 4 q q35.2 TRIML2 189012809 4.98E− 1.20 0.062 0.052 A (SEQ ID NO: 0402) 03 tcttgctcacggggtc[A/G] gtgatggggaccgagt 03 rs6849766 4 q q35.2 ZFP42| 189010521 2.37E− 1.10 0.174 0.161 A (SEQ ID NO: 0403) TRIML2 02 agtgtttcaaataatt[A/G] tctcacttccagctca 01 rs4611976 4 q q35.2 ZFP42| 188990955 1.78E− 1.39 0.055 0.040 C (SEQ ID NO: 0404) TRIML2 06 acctggagagaggggc[A/C] cagctcagagctttcc 03 rs1895435 5 p p13.2 GDNF|  37892952 8.57E− 1.19 0.104 0.089 C (SEQ ID NO: 0405) EGFLAM 04 catctgtggatatggc[A/C] gttttaccctcctggc 03 rs13362367 5 p p13.3 LOC729862|  29329716 2.03E− 0.89 0.207 0.227 A (SEQ ID NO: 0406) LOC 03 gttttgaccccttgga[A/G] 100130803 acactcatgaacaacc 03 rs12109819 5 p p13.3 PDZD2  32068026 4.13E− 0.93 0.302 0.317 A (SEQ ID NO: 0407) 02 tgtaccccatggtttt[A/G] gcatcattgactatta 03 rs2303748 5 p p14.3 CDH12  21760602 8.97E− 1.13 0.279 0.256 C (SEQ ID NO: 0408) 04 aagaaaagtattgatt[A/C] ctccctttgtgccttt 03 rs6555477 5 p p15.31 ADCY2   7587939 2.36E− 1.13 0.316 0.290 A (SEQ ID NO: 0409) 04 aagaggatagggaaac[A/G] ttgagagaatcggttg 02 exm443730 5 p p15.31 C5orf49   7831992 2.13E− 8.93 0.006 0.001 A (SEQ ID NO: 0410) 08 atgtgcccaaagccgg[A/G] ttccttgaggctgggg 03 rs275447 5 p p15.31 POLS|   6825016 3.29E− 1.13 0.182 0.164 A (SEQ ID NO: 0411) LOC442132 03 ttttctgtgccttcac[A/G] tgtacttacacgcaca 03 rs13177725 5 p p15.31 POLS|   6795764 1.21E− 0.90 0.194 0.210 G (SEQ ID NO: 0412) LOC442132 02 gattagtgcacttaca[A/G] ggggatgaagagacca 03 rs275442 5 p p15.31 POLS|   6827513 7.70E− 1.11 0.438 0.412 A (SEQ ID NO: 0413) LOC442132 04 atgaataagctaactt[A/G] agccgaaatgttaaca 03 rs37006 5 p p15.33 CLPTM1L|   1355058 2.05E− 0.93 0.417 0.435 A (SEQ ID NO: 0414) SLC6A3 02 cactgcaacattttca[A/G] acttgaatctcacaga 03 rs6861105 5 p p15.33 IRX4|   1897640 4.38E− 0.80 0.064 0.079 G (SEQ ID NO: 0415) IRX2 04 tgccagctgaggctcc[A/G] gcagacacaggtttgc 03 rs12188301 5 p p15.33 NDUFS6|   1847639 9.14E− 0.83 0.108 0.127 A (SEQ ID NO: 0416) IRX4 05 agaaatgggatgtagc[A/G] tgagttgtgagttgtt 02 exm442113 5 p p15.33 TERT   1293767 9.52E− 7.19 0.011 0.002 A (SEQ ID NO: 0417) 14 gctcgcagcgggcagt[A/G] cgtcttgaggagcacc 03 rs7722066 5 q q11.2 LOC257396|  52417217 2.80E− 0.89 0.386 0.415 A (SEQ ID NO: 0418) FST 04 catatgtttgtgtgag[A/C] agatctttgtaagttt 03 rs10060367 5 q q12.3 FLJ46010|  65859130 3.38E− 1.12 0.212 0.193 A (SEQ ID NO: 0419) MAST4 03 agagtcgagtagatga[A/G] gtgtgcttcaggtttt 03 rs10056426 5 q q12.3 MAST4  66203615 8.76E− 1.15 0.097 0.085 G (SEQ ID NO: 0420) 03 aaaatctcacaaatgc[A/G] attcaagtaagttgaa 03 rs26923 5 q q12.3 MAST4  66170504 5.15E− 1.16 0.098 0.086 C (SEQ ID NO: 0421) 03 tacagcagaccgaaac[A/C] atgtattttagaatta 03 rs734828 5 q q12.3 MAST4  66221262 6.08E− 1.16 0.101 0.088 G (SEQ ID NO: 0422) 03 aatcactctaaacaac[A/G] catttaataggttcca 02 rs12521058 5 q q13.3 LOC728723  76426987 3.31E− 1.14 0.416 0.384 A (SEQ ID NO: 0423) 05 aataaacgagagacat[A/C] tggagaaaggagacct 03 rs7732628 5 q q13.3 LOC728723  76435346 4.66E− 0.89 0.413 0.440 G (SEQ ID NO: 0424) 04 atctgagaaaattctc[A/G] gtcactgtcacttcaa 02 rs2972341 5 q q13.3 LOC728723|  76468843 1.15E− 0.90 0.443 0.468 A (SEQ ID NO: 0425) PDE8B 05 cactgattagctgatg[A/G] gactctaccctatata 03 rs6862414 5 q q13.3 LOC728723|  76454559 9.74E− 0.90 0.248 0.269 G (SEQ ID NO: 0426) PDE8B 05 ggacaggccacaccca[A/G] aggaaaacctggagtc 03 rs16875951 5 q q14.1 ARSB  78101191 2.19E− 1.11 0.137 0.125 A (SEQ ID NO: 0427) 02 gaacctaaactgttgt[A/G] attttataccaagtat 02 rs1129770 5 q q14.1 CMYA5  79086883 2.40E− 1.10 0.195 0.181 A (SEQ ID NO: 0428) 06 tttggtgagaggagac[A/G] gctgacggagtaagta 03 rs293045 5 q q15 MCTP1  94289131 7.79E− 1.33 0.037 0.028 G (SEQ ID NO: 0429) 04 actttttgttgtttca[A/G] aagagtggttctcttg 03 rs1990745 5 q q21.2 NUDT12| 103381922 1.59E− 1.15 0.150 0.133 A (SEQ ID NO: 0430) RAB9P1 03 cactttggtattaatc[A/G] ttgatcttgcagttag 03 rs10464035 5 q q21.3 LOC 106562841 2.35E− 1.14 0.167 0.150 A (SEQ ID NO: 0431) 100287833| 03 gacactccttgagact[A/G] EFNA5 caaaccacatacctgg 03 rs10455070 5 q q21.3 LOC 106569691 8.74E− 1.11 0.186 0.170 A (SEQ ID NO: 0432) 100287833| 03 aaacctaaaagatcaa[A/G] EFNA5 ttggctaaacacgtac 03 rs4957696 5 q q21.3 LOC 106558682 2.53E− 1.14 0.168 0.151 C (SEQ ID NO: 0433) 100287833| 03 tccgggcatttcttgg[A/C] EFNA5 tatttctttaataatg 03 rs11749864 5 q q22.2 MCC 112612123 1.06E− 1.19 0.058 0.049 G (SEQ ID NO: 0434) 02 agaaactgagcagtgt[A/G] ttgtgcagaattggtg 03 rs11740353 5 q q22.2 MCC 112577696 1.12E− 1.19 0.057 0.049 A (SEQ ID NO: 0435) 02 cagcagaatagagaac[A/G] accaaatcaaacaaca 03 rs1965429 5 q q22.2 MCC 112679373 1.09E− 0.92 0.349 0.368 C (SEQ ID NO: 0436) 02 atggcctgtgacatag[A/C] tagcatttaataaaca 03 rs10519343 5 q q22.2 MCC 112592606 5.94E− 1.20 0.058 0.049 A (SEQ ID NO: 0437) 03 acccataaaccattct[A/G] agggccagattaaaac 03 rs17333442 5 q q22.2 YTHDC2| 112947050 1.27E− 0.88 0.101 0.113 C (SEQ ID NO: 0438) KCNN2 02 aaatatgttatattta[A/C] tggcagttatctttct 03 rs2112614 5 q q22.3 CCDC112| 114812584 1.10E− 1.16 0.135 0.118 G (SEQ ID NO: 0439) FEM1C 03 taaagtaaacgtactc[A/G] tcttagcttagacaca 03 rs9637896 5 q q22.3 YTHDC2| 113561408 9.39E− 1.17 0.132 0.115 G (SEQ ID NO: 0440) KCNN2 05 agaaaatcaaattttt[A/G] taagacttaccaaaaa 03 rs2896965 5 q q23.1 HSD17B4| 118921139 2.37E− 0.87 0.136 0.153 G (SEQ ID NO: 0441) FAM170A 03 tagatggtaaccaggc[A/G] tgaagagacagctgac 03 rs37391 5 q q23.2 CSNK1G3| 123525965 2.95E− 0.88 0.308 0.334 G (SEQ ID NO: 0442) ZNF608 04 agacaagcagcgcctc[A/G] tttatgtgatgtattt 02 rs7721313 5 q q31.1 H2AFY 134673961 3.90E− 1.20 0.076 0.065 C (SEQ ID NO: 0443) 02 ggttaagagctcagga[T/C] ttcccggagtcacaca 03 rs40273 5 q q31.1 TCF7 133482348 3.98E− 0.80 0.044 0.054 G (SEQ ID NO: 0444) 03 atttcagaggctgcag[A/G] acttctgcctgaacct 02 rs165179 5 q q31.2 UBE2D2| 138985694 1.26E− 1.29 0.074 0.058 G (SEQ ID NO: 0445) UBE2D2 05 atgagactgaatcccc[A/G] gagacctacacttgaa 02 rs10476878 5 q q32 POU4F3| 145797485 4.95E− 0.85 0.194 0.221 G (SEQ ID NO: 0446) TCERG1 05 caaacttatcacagta[A/G] tcacatttttaaggag 03 rs979893 5 q q32 POU4F3| 145797020 8.30E− 0.87 0.179 0.200 A (SEQ ID NO: 0447) TCERG1 04 agtgtgttaagctttc[A/C] tgctcagaaatgacag 03 rs10056189 5 q q32 POU4F3| 145804118 4.51E− 0.87 0.121 0.136 A (SEQ ID NO: 0448) TCERG1 03 ccagtaccaccctttg[A/G] agctttacttgttttg 02 rs7718446 5 q q32 POU4F3| 145749535 4.40E− 0.87 0.264 0.292 G (SEQ ID NO: 0449) TCERG1 06 tccaacacttagggta[A/G] gtaagtagctagttac 02 rs11747475 5 q q32 POU4F3| 145784922 5.98E− 0.85 0.194 0.220 G (SEQ ID NO: 0450) TCERG1 05 cacgatgtcatgtgtt[A/G] attgagttgtatactt 02 rs6886412 5 q q32 POU4F3| 145777478 5.42E− 0.86 0.262 0.291 G (SEQ ID NO: 0451) TCERG1 06 atgcttcaccgtctac[A/G] tcccctaattctaacc 02 exm494153 5 q q32 PPARGC1B 149213060 2.10E− 20.5 0.008 0.000 A (SEQ ID NO: 0452) 16 6 gagagctctgtgtgcc[A/C] cgtgcggcgttctcgg 02 exm497501 5 q q33.1 FAT2 150946613 4.47E− Inf 0.004 0.000 G (SEQ ID NO: 0453) 11 aaacgcccttttatca[A/G] tcttactgctggtcaa 03 rs1438937 5 q q33.1 NMUR2| 152370448 2.03E− 0.89 0.412 0.441 A (SEQ ID NO: 0454) GRIA1 04 cccaagcaaatgatag[A/C] tattgccaattaaact 03 rs918509 5 q q33.2 GALNT10 153762653 4.81E− 0.88 0.225 0.249 A (SEQ ID NO: 0455) 04 ccagtgactgccaacc[A/G] tggccacacataagca 02 rs954929 5 q q34 LOC285629| 160380401 2.37E− 1.07 0.359 0.343 A (SEQ ID NO: 0456) GABRB2 05 ctctctatactacccc[A/G] tcagtgactcgcttta 02 rs7725726 5 q q35.1 GABRP 170215670 1.65E− 1.24 0.090 0.074 A (SEQ ID NO: 0457) 05 tgagtctcttcactga[A/G] aggtgagctttgctac 03 rs11134653 5 q q35.1 GABRP 170213757 6.23E− 1.22 0.087 0.072 A (SEQ ID NO: 0458) 05 cttacaactgtgccac[A/G] catatctagaatcctc 02 rs258878 5 q q35.2 BOD1 173051169 1.51E− 0.89 0.357 0.383 A (SEQ ID NO: 0459) 02 accaccaggagaggtt[C/A] tctctcttcttggagc 02 exm505619 5 q q35.2 EIF4E1B 176072243 1.70E− 50.7 0.005 0.000 A (SEQ ID NO: 0460) 12 3 cctcctccaactcacc[A/G] tctccagccacagccg 03 rs11134853 5 q q35.2 HMP19| 173970989 1.81E− 1.18 0.163 0.142 C (SEQ ID NO: 0461) LOC 04 gtagtatgaacaaaag[A/C] 100127922 gccctgggcttggagt 01 rs2770967 5 q q35.3 LOC 180678717 4.44E− 1.28 0.094 0.075 G (SEQ ID NO: 0462) 100289627| 06 tgtgataaatttaatc[A/G] TRIM52 tagtctgtccaaacca 03 rs7727897 5 q q35.3 LOC202181 177047009 8.02E− 1.15 0.097 0.085 G (SEQ ID NO: 0463) 03 cagagtcttcccccca[A/G] tctgactcttctccat 03 rs3940643 5 q q35.3 RASGEF1C 179585309 6.16E− 1.13 0.302 0.277 A (SEQ ID NO: 0464) 04 tttaaatacaggagac[A/G] ggagcccaacacataa 03 rs4440459 6 p p12.1 ELOVL5|  53293410 8.62E− 1.17 0.136 0.119 A (SEQ ID NO: 0465) GCLC 04 tgagcctgacctccaa[A/C] acctcagcagcagcat 02 rs9370209 6 p p12.1 ELOVL5|  53296156 4.28E− 1.21 0.142 0.121 A (SEQ ID NO: 0466) GCLC 05 atgagggttttagaat[A/G] tatttgaatgctgaca 03 rs6458934 6 p p12.1 ELOVL5|  53291466 2.82E− 1.18 0.136 0.117 G (SEQ ID NO: 0467) GCLC 04 taactccaagttaaag[A/G] ctatttctaccacatc 03 rs12192659 6 p p12.1 FAM83B  54726327 2.63E− 1.12 0.485 0.456 A (SEQ ID NO: 0468) 04 tgacactgctgacaga[A/G] gaagaccccacctcca 03 rs13200042 6 p p12.1 FAM83B|  55033223 2.49E− 0.89 0.212 0.232 G (SEQ ID NO: 0469) HCRTR2 03 tctactgtggaaacag[A/G] atagagtaacagcaaa 03 rs3134704 6 p p12.1 HCRTR2  55072273 1.42E− 0.91 0.219 0.236 G (SEQ ID NO: 0470) 02 atgtgatttattttaa[A/G] cctcaccatttgaagt 02 exm555738 6 p p12.2 GSTA5  52696737 1.81E− Inf 0.003 0.000 A (SEQ ID NO: 0471) 08 cagaaacttcttcacc[A/G] tgggcaggttgctgat 03 rs4712023 6 p p12.2 LOC  52758653 6.91E− 1.15 0.072 0.064 A (SEQ ID NO: 0472) 100287869| 05 taagttgttgaaccac[A/G] GSTA3 agcatgacagtcttta 02 rs9296695 6 p p12.2 LOC  52758076 4.34E− 1.13 0.069 0.061 A (SEQ ID NO: 0473) 100287869| 05 gaaaaccttgacaaac[A/G] GSTA3 gagctggaaaaccatg 03 rs2505276 6 p p12.3 TFAP2B|  51087831 2.04E− 0.89 0.430 0.459 A (SEQ ID NO: 0474) LOC646517 04 cagaggatgccagttt[A/G] cttgaatgccaaaatt 03 rs9381940 6 p p12.3 TFAP2B|  51073648 2.14E− 0.91 0.383 0.406 A (SEQ ID NO: 0475) LOC646517 03 tcattttgatcactct[A/G] tggcatttgacacttt 02 exm551051 6 p p21.1 CAPN11  44143862 1.57E− Inf 0.005 0.000 A (SEQ ID NO: 0476) 14 gctggtgagagggcac[A/G] cttactctgtgactgg 02 rs9381299 6 p p21.1 SLC29A1|  44211867 4.19E− 1.14 0.141 0.126 G (SEQ ID NO: 0477) HSP90AB1 05 aaaggaacagagcccc[A/G] ttagaggaaccatagc 03 rs3187 6 p p21.1 SLC35B2  44222047 6.79E− 1.20 0.106 0.091 A (SEQ ID NO: 0478) 05 cattggagcctacacc[A/G] cttgtgcttttctcac 02 exm542389 6 p p21.31 ETV7  36339143 2.60E− 8.74 0.014 0.002 A (SEQ ID NO: 0479) 19 ggtctgttccttcccc[A/G] cgatgccgcaggcccc 02 rs2499724 6 p p21.31 GRM4  34086671 1.08E− 0.89 0.441 0.468 C (SEQ ID NO: 0480) 02 aatgaatacaactgta[A/C] aaactggaaccaaacc 02 rs2451330 6 p p21.31 GRM4|  34118586 8.40E− 0.88 0.380 0.411 G (SEQ ID NO: 0481) HMGA1 05 agttgagagaagccag[A/G] gtgaaattcctcctgc 02 rs914813 6 p p21.31 GRM4|  34103954 1.44E− 0.87 0.358 0.392 G (SEQ ID NO: 0482) HMGA1 05 tagggataaaaatacc[A/G] tgaagctcatagggat 03 rs2070600 6 p p21.32 AGER  32151443 1.63E− 0.73 0.038 0.051 A (SEQ ID NO: 0483) 04 tcgtgtccttcccaac[A/G] gctccctcttccttcc 02 rs176248 6 p p21.32 BRD2|HLA-  32965942 2.07E− 0.85 0.244 0.275 A (SEQ ID NO: 0484) DOA 05 agaagagagagagtaa[A/G] tgtattccaccaagaa 03 rs2076524 6 p p21.32 BTNL2  32370684 6.48E− 0.91 0.268 0.287 G (SEQ ID NO: 0485) 03 tcctgctgatctgagc[A/G] tgtgggtcctagaggc 03 rs2076525 6 p p21.32 BTNL2  32370616 4.01E− 0.90 0.267 0.287 G (SEQ ID NO: 0486) 03 tttatcaagagacatt[A/G] tctatcatatagcaat 03 rs2395175 6 p p21.32 BTNL2|HLA-  32405026 1.78E− 0.87 0.150 0.168 A (SEQ ID NO: 0487) DRA 03 ctgcaacatcagcaga[A/G] gcttcctgtgggttcc 03 rs3763316 6 p p21.32 BTNL2|HLA-  32376746 5.49E− 0.91 0.267 0.287 A (SEQ ID NO: 0488) DRA 03 ctaaggggaggtgact[A/G] gtaagtttcaggtggc 03 rs2073045 6 p p21.32 C6orf10  32339548 2.82E− 0.91 0.350 0.373 A (SEQ ID NO: 0489) 03 tcagagagagatcaag[A/G] taaaacgaaaaactca 03 rs2050188 6 p p21.32 C6orf10|  32339897 1.47E− 1.11 0.365 0.341 G (SEQ ID NO: 0490) BTNL2 03 tacaaagattaatgat[A/G] tacaatctctggcctt 03 rs9268474 6 p p21.32 C6orf10|  32357165 4.56E− 0.90 0.267 0.287 G (SEQ ID NO: 0491) BTNL2 03 tatttcttgatgaaat[A/G] tgtaagcctcccttta 03 rs9268461 6 p p21.32 C6orf10|  32351901 1.33E− 0.92 0.268 0.286 A (SEQ ID NO: 0492) BTNL2 02 tttggtgccttcctac[A/C] gttatggaaggaagct 03 rs9268456 6 p p21.32 C6orf10|  32349946 6.07E− 0.91 0.268 0.287 A (SEQ ID NO: 0493) BTNL2 03 cctatagtcaagtaag[A/C] ctgtaataataaatat 03 rs9268403 6 p p21.32 C6orf10|  32341473 6.93E− 0.91 0.268 0.287 G (SEQ ID NO: 0494) BTNL2 03 gggagatctcttacac[A/G] tgatgtttctttcaga 03 rs9268425 6 p p21.32 C6orf10|  32344376 8.36E− 0.91 0.268 0.287 A (SEQ ID NO: 0495) BTNL2 03 agaaatccacttagat[A/G] tctaccctacttcccc 03 rs9268428 6 p p21.32 C6orf10|  32344973 5.96E− 0.91 0.268 0.287 A (SEQ ID NO: 0496) BTNL2 03 tttcttaacacagcag[A/C] aaaattgttttatgtc 03 rs2894252 6 p p21.32 C6orf10|  32345443 6.38E− 0.91 0.268 0.287 A (SEQ ID NO: 0497) BTNL2 03 gtagattctaatctta[A/G] gccctttgccatagac 03 rs2395157 6 p p21.32 C6orf10|  32348145 6.94E− 0.91 0.268 0.287 G (SEQ ID NO: 0498) BTNL2 03 agaaaataaaaactat[A/G] taatcttagatggcac 03 rs9268454 6 p p21.32 C6orf10|  32349711 6.03E− 0.91 0.268 0.287 G (SEQ ID NO: 0499) BTNL2 03 ataacactgatgatat[A/G] gatttgaggtgagaga 02 rs1061807 6 p p21.32 EGFL8|  32136838 1.27E− 1.18 0.264 0.234 A (SEQ ID NO: 0500) AGPAT1 05 gggggtcaagagtgga[A/G] actgcaccgaggcaag 02 exm536563 6 p p21.32 HLA-DQA2  32714067 3.35E− Inf 0.026 0.000 A (SEQ ID NO: 0501) 29 agagactttggtctgc[A/G] ccctggggttgtctgt 02 exm536439 6 p p21.32 HLA-DQB1  32634282 2.16E− 5.59 0.007 0.001 G (SEQ ID NO: 0502) 08 ctgcacttaccgggag[A/G] gtctctgccctcagcc 03 rs1964995 6 p p21.32 HLA-DRA|  32449411 2.88E− 0.91 0.417 0.440 G (SEQ ID NO: 0503) HLA-DRB5 03 agaatcaaggaataag[A/G] aaaataatgtgagctg 03 rs9267833 6 p p21.32 NOTCH4  32177900 8.69E− 1.13 0.272 0.249 G (SEQ ID NO: 0504) 04 catcttcttcaggaag[A/G] tgtccctaacttctcc 02 rs206015 6 p p21.32 NOTCH4  32182759 6.17E− 0.81 0.098 0.118 A (SEQ ID NO: 0505) 05 ttcgccctgggattta[A/G] tgctcttctttctgct 03 rs2071277 6 p p21.32 NOTCH4  32171683 3.77E− 1.12 0.510 0.482 G (SEQ ID NO: 0506) 04 tgatgcagtgtgtgac[A/G] tctaatctcccccata 02 rs206016 6 p p21.32 NOTCH4  32181182 4.04E− 0.81 0.096 0.116 A (SEQ ID NO: 0507) 05 tatatgatattttatt[A/G] tttttagatagggtct 03 rs394657 6 p p21.32 NOTCH4  32187023 7.27E− 1.11 0.469 0.442 G (SEQ ID NO: 0508) 04 ggagcattctgggttg[A/G] cctgagcaaaggctgc 03 rs3134799 6 p p21.32 NOTCH4  32184221 6.64E− 1.11 0.464 0.438 A (SEQ ID NO: 0509) 04 tctgcttatctttcaa[A/G] actcatctcagccatc 02 rs2071286 6 p p21.32 NOTCH4  32179896 6.41E− 1.16 0.225 0.200 A (SEQ ID NO: 0510) 05 tccagctacactcaac[A/G] catttcaccccacccc 03 rs9357138 6 p p21.32 NOTCH4|  32219838 2.54E− 1.14 0.154 0.138 A (SEQ ID NO: 0511) C6orf10 03 tattaattgccccaga[A/G] atctatcctcacatcc 02 rs9267810 6 p p21.32 PPT2  32121594 3.97E− 1.18 0.269 0.237 G (SEQ ID NO: 0512) 06 tctggctccgcagcag[A/G] acacgaagtttgcatt 02 rs2269424 6 p p21.32 PPT2|  32132233 9.13E− 1.18 0.265 0.234 A (SEQ ID NO: 0513) EGFL8 06 ggagccctttgctggg[A/G] tggggatgagggtagt 03 rs35502919 6 p p21.33 BAT2  31604355 1.15E− 0.72 0.034 0.047 A (SEQ ID NO: 0514) 04 ctggtggccaaagtgg[A/C] tttctcccttcagggg 03 rs3130977 6 p p21.33 C6orf15|  31081989 6.61E− 0.89 0.310 0.335 G (SEQ ID NO: 0515) PSORS1C1 04 aagtctggaatcagca[A/G] aaatgtattacattga 02 exm- 6 p p21.33 C6orf25  31692970 1.15E− Inf 0.017 0.003 A (SEQ ID NO: 0516) rs407283 13 atagaaataagtgcta[A/G] actgggagttgggaga 03 rs3132550 6 p p21.33 CDSN  31086048 3.46E− 0.87 0.212 0.236 A (SEQ ID NO: 0517) 04 gtgagagcccaggctg[A/G] ggtcaggaatggaaac 03 rs2844456 6 p p21.33 EHMT2  31864674 1.55E− 0.73 0.035 0.048 G (SEQ ID NO: 0518) 04 gctaaaacgggcccca[A/G] ttggaccgtcaccttc 02 rs9263582 6 p p21.33 HCG22|  31070664 4.06E− 0.77 0.063 0.080 A (SEQ ID NO: 0519) C6orf15 05 cacttaaagcccaaag[A/G] tggccggctgtggtgg 01 rs35718543 6 p p21.33 HCG27|  31177845 1.38E− 1.28 0.106 0.085 A (SEQ ID NO: 0520) HLA-C 06 tgtggatcttcagcac[A/G] tctacaactccctcca 03 rs2523457 6 p p21.33 HLA-B|  31365707 3.63E− 0.90 0.292 0.313 A (SEQ ID NO: 0521) MICA 03 acaaaccttcttggaa[A/G] gtggaaagttttgcaa 02 rs2853925 6 p p21.33 HLA-C|  31264922 1.63E− 0.81 0.112 0.135 G (SEQ ID NO: 0522) HLA-B 05 acaaaagctaccagat[A/G] aaaacactcactatgg 02 rs9264869 6 p p21.33 HLA-C|  31271630 1.33E− 0.81 0.112 0.135 G (SEQ ID NO: 0523) HLA-B 05 cctgagagatctgagt[A/G] atcaagacccagtgtt 02 rs7759127 6 p p21.33 HLA-C|  31240988 5.21E− 0.80 0.110 0.133 C (SEQ ID NO: 0524) HLA-B 06 attcggtatttaatac[A/C] ttttgtgtgactgcct 02 rs2524043 6 p p21.33 HLA-C|  31257012 1.42E− 0.81 0.112 0.135 G (SEQ ID NO: 0525) HLA-B 05 ctttcatttattgaac[A/G] ccttagatatgagcta 02 rs2524132 6 p p21.33 HLA-C|  31264912 1.67E− 0.81 0.112 0.135 A (SEQ ID NO: 0526) HLA-B 05 ttacagctcaacaaaa[A/G] ctaccagataaaaaca 02 rs364415 6 p p21.33 HLA-C|  31273224 1.33E− 0.81 0.112 0.135 A (SEQ ID NO: 0527) HLA-B 05 ggaggaagtgtggggt[A/G] tgggtagactcctcct 02 rs3873385 6 p p21.33 HLA-C|  31269308 1.91E− 0.84 0.137 0.159 A (SEQ ID NO: 0528) HLA-B 05 gtgtgtgatgcagtat[A/G] gggtagaaccaggaga 02 rs9264870 6 p p21.33 HLA-|C  31271662 1.51E− 0.81 0.113 0.135 A (SEQ ID NO: 0529) HLA-B 05 ttcacacatggaaaat[A/G] aggtggaaaaggagaa 02 rs2524160 6 p p21.33 HLA-C|  31259854 1.77E− 0.81 0.113 0.135 A (SEQ ID NO: 0530) HLA-B 05 gtttgtgataaggagc[A/G] ttggggaggagatttg 02 rs2524048 6 p p21.33 HLA-C|  31256561 1.56E− 0.81 0.112 0.135 G (SEQ ID NO: 0531) HLA-B 05 tttaaggaggctaact[A/G] cttccacattagatca 03 rs2524050 6 p p21.33 HLA-C|  31255541 5.39E− 0.82 0.109 0.130 G (SEQ ID NO: 0532) HLA-B 05 cttttttgtcttcccc[A/G] tgcattcgcccccaca 02 rs2524162 6 p p21.33 HLA-C|  31259750 4.11E− 0.82 0.123 0.146 A (SEQ ID NO: 0533) HLA-B 05 gacccaacagtaagac[A/G] tttctccttttggtaa 02 rs2524115 6 p p21.33 HLA-C|  31265554 1.44E− 0.81 0.112 0.135 A (SEQ ID NO: 0534) HLA-B 05 cgttgaagaatcagta[A/C] aatttggagactttga 01 rs2853930 6 p p21.33 HLA-C|  31255424 3.02E− 0.79 0.106 0.131 C (SEQ ID NO: 0535) HLA-B 06 atcctgcaccttttcc[A/C] gtcaaatccccattcc 03 rs13220225 6 p p21.33 IER3|DDR1  30747802 1.36E− 1.17 0.187 0.165 A (SEQ ID NO: 0536) 04 taagagaagactcacc[A/G] ttctgaggctgtctga 02 rs28780111 6 p p21.33 IER3|DDR1  30720311 4.13E− 1.18 0.188 0.164 A (SEQ ID NO: 0537) 05 tccttcccagaaaacc[A/G] cctcagggctcacccc 02 rs2535323 6 p p21.33 IER3|DDR1  30718180 3.71E− 1.18 0.196 0.171 G (SEQ ID NO: 0538) 05 gaactggaatgagaaa[A/G] taacctctaactgcta 03 rs10947091 6 p p21.33 IER3|DDR1  30747216 1.51E− 1.11 0.322 0.299 A (SEQ ID NO: 0539) 03 agctcctactcagata[A/G] cagaactcacaaactt 03 rs986475 6 p p21.33 LST1|NCR3  31556709 8.74E− 1.19 0.100 0.086 G (SEQ ID NO: 0540) 04 ggtcaaatagtaattt[A/G] ttgggtgaatgacagt 03 rs6916921 6 p p21.33 NFKBIL1  31520426 8.60E− 1.19 0.104 0.088 A (SEQ ID NO: 0541) 04 atttaccagatcaacc[A/G] ttctcaatgctcttta 03 rs9263699 6 p p21.33 PSORS1C1  31093699 1.16E− 1.14 0.211 0.191 A (SEQ ID NO: 0542) 03 tggaagaatgtgtcca[A/G] gctgtgcttccccttt 03 rs3815087 6 p p21.33 PSORS1C1  31093587 6.83E− 1.14 0.213 0.192 A (SEQ ID NO: 0543) 04 ccatcacccccggacc[A/G] tgggctccatgccagt 03 rs9263715 6 p p21.33 PSORS1C1  31095801 6.12E− 1.14 0.211 0.190 A (SEQ ID NO: 0544) 04 tcctctcctgtagacc[A/G] ctggctcatgaaataa 03 rs9468877 6 p p21.33 PSORS1C3  31142903 3.81E− 1.16 0.160 0.141 A (SEQ ID NO: 0545) 04 cagactgctggctctg[A/G] gcatctgagcagcgcc 03 rs9393228 6 p p22.3 FLJ22536  22112043 1.16E− 1.11 0.437 0.412 A (SEQ ID NO: 0546) 03 agggttttcttgaatg[A/G] catttctcattgctaa 03 rs952578 6 p p22.3 FLJ22536  21884519 1.16E− 1.11 0.357 0.333 A (SEQ ID NO: 0547) 03 agaatagacgtgttag[A/G] aaccaggttagcctgg 03 rs199091 6 p p22.3 LOC389370|  23533562 1.76E− 1.13 0.359 0.331 G (SEQ ID NO: 0548) LOC 04 tcttgggggtcttttg[A/G] 100129616 gggaacagagaacaat 01 rs6907340 6 p p22.3 RNF144B|  19803768 3.67E− 1.20 0.416 0.373 A (SEQ ID NO: 0549) ID4 10 ttgatgatggtgatat[A/G] gaatgattaataacca 02 rs7759616 6 p p22.3 RNF144B|  19794585 1.70E− 1.14 0.521 0.487 A (SEQ ID NO: 0550) ID4 05 tgatgggagagaaata[A/G] gaattcaacttgtagc 02 rs760794 6 p p22.3 RNF144B|  19790560 1.84E− 1.17 0.469 0.431 A (SEQ ID NO: 0551) ID4 07 tttttccctgaaactc[A/G] gccaaaagtttttcct 01 rs6904518 6 p p22.3 RNF144B|  19798704 7.31E− 1.19 0.426 0.385 G (SEQ ID NO: 0552) ID4 10 gctatattaaaagaaa[A/G] tagacttcaaagcaaa 02 rs7766034 6 p p22.3 RNF144B|  19753061 5.48E− 1.15 0.464 0.429 A (SEQ ID NO: 0553) ID4 06 aggggcctaagcccag[A/G] tgtcagaggcacagta 02 rs6916251 6 p p22.3 RNF144B|  19761215 3.39E− 1.16 0.465 0.428 G (SEQ ID NO: 0554) ID4 07 gtttccagccacctct[A/G] tttccattcccttaaa 02 rs6920825 6 p p22.3 RNF144B|  19732492 6.00E− 1.16 0.223 0.198 G (SEQ ID NO: 0555) ID4 05 gacgcagtctgtaggc[A/G] cttggcaagtgtttgc 02 rs6456259 6 p p22.3 RNF144B|  19761718 5.65E− 1.18 0.180 0.157 G (SEQ ID NO: 0556) ID4 05 tcccctgccactccct[A/G] tttaatgcctttgtaa 01 rs2206034 6 p p22.3 RNF144B|  19796863 2.22E− 1.16 0.479 0.441 A (SEQ ID NO: 0557) ID4 08 gtgtgagggactcctc[A/G] taactcctgggcaagg 02 rs2223361 6 p p22.3 RNF144B|  19790809 1.76E− 1.17 0.469 0.431 A (SEQ ID NO: 0558) ID4 07 gttgtcatgagttacc[A/G] tgattaaagtggtgga 01 rs6903595 6 p p22.3 RNF144B|  19798141 9.39E− 1.18 0.423 0.383 A (SEQ ID NO: 0559) ID4 09 tataatctttgtctca[A/G] tagtcaaatacttaga 02 rs7739264 6 p p22.3 RNF144B|  19785588 3.29E− 0.90 0.451 0.477 G (SEQ ID NO: 0560) ID4 05 tccccatagctatcca[A/G] ttgagccagaaccatt 03 rs2842934 6 p p22.3 TPMT  18139214 2.14E− 1.12 0.236 0.216 G (SEQ ID NO: 0561) 03 tgcgatcacctggatt[A/G] atggcaactaatgctc 03 rs2842947 6 p p22.3 TPMT  18132822 1.62E− 1.12 0.237 0.216 G (SEQ ID NO: 0562) 03 tctggaggtggagtct[A/G] aggatactgctcttag 03 rs2842950 6 p p22.3 TPMT  18135178 3.62E− 1.11 0.233 0.215 A (SEQ ID NO: 0563) 03 agtctagccaggctcc[A/G] tagaaactggagtgcc 02 rs9462160 6 p p24.1 LOC389369|  11834883 1.60E− 1.12 0.277 0.254 G (SEQ ID NO: 0564) HIVEP1 06 gaattttggaattcag[A/G] tatcagaaaaaagctg 03 rs12193156 6 p p24.1 PHACTR1  13203570 4.07E− 0.90 0.264 0.285 G (SEQ ID NO: 0565) 03 agttatgtaaacagga[A/G] gtgcagcatagtgtct 03 rs201051 6 p p25.1 LY86|RREB1   6721713 1.50E− 1.15 0.261 0.236 A (SEQ ID NO: 0566) 04 ttctttcatccttatg[A/G] cctttcttgtataggt 02 rs11242762 6 p p25.2 LOC   2379182 2.87E− 0.88 0.446 0.477 G (SEQ ID NO: 0567) 100128372| 05 atatatcattttattt[A/G] C6orf195 atttcccagtcacctt 03 rs9503159 6 p p25.2 LOC   2371304 7.88E− 0.88 0.445 0.476 G (SEQ ID NO: 0568) 100128372| 05 cgtacccatgtgtcac[A/G] C6orf195 agtacacatgctIttc 03 rs4959652 6 p p25.2 LOC   2386913 8.38E− 1.10 0.420 0.397 A (SEQ ID NO: 0569) 100128372| 05 aatcattttttcaaaa[A/G] C6orf195 tgtagtcttttgtgag 03 rs1715026 6 q q11.1 KHDRBS2  62515691 2.76E− 1.08 0.287 0.271 G (SEQ ID NO: 0570) 02 aggaggtgattagatc[A/G] tagaggttgttcccac 03 rs6929584 6 q q13 BAI3|  70382870 8.84E− 0.83 0.084 0.099 G (SEQ ID NO: 0571) LMBRD1 04 ctttgaagtccttctg[A/G] aaaatacctaaattag 03 rs1114785 6 q q13 BAI3|  70367148 4.75E− 0.89 0.180 0.198 A (SEQ ID NO: 0572) LMBRD1 03 aacccactccactaag[A/G] ccttcagtctgtgctc 02 exm563585 6 q q14.2 SNAP91  84303230 3.86E− 4.18 0.011 0.003 G (SEQ ID NO: 0573) 09 ctccgctgccaccgcc[A/G] ccactgctcctcctgc 02 rs9359587 6 q q14.3 KIAA1009|  85105960 4.29E− 1.15 0.232 0.208 G (SEQ ID NO: 0574) TBX18 05 tttgccatactaattt[A/G] gtaactttagctaggt 03 rs9294298 6 q q14.3 KIAA1009|  85147411 8.77E− 0.92 0.385 0.405 A (SEQ ID NO: 0575) TBX18 03 gcctctagtcactaag[A/G] aaagtctaagtatctt 03 rs4053608 6 q q15 BACH2  90787599 2.00E− 1.11 0.290 0.268 A (SEQ ID NO: 0576) 03 ttcaggattagatgct[A/G] agacttcaaatcagtc 03 rs9342219 6 q q15 BACH2  90756453 6.39E− 1.10 0.305 0.285 A (SEQ ID NO: 0577) 03 acttgtttacaaaagc[A/G] tctctataggtctgtg 03 rs453561 6 q q15 GABRR1  89904872 1.78E− 1.11 0.404 0.380 A (SEQ ID NO: 0578) 03 aagataaataagacaa[A/G] taacacattaaaaagc 03 rs6908196 6 q q16.2 PRDM13| 100185261 6.25E− 0.90 0.400 0.427 C (SEQ ID NO: 0579) MCHR2 04 atgggcaaacttctct[A/C] atgctaacagtgatga 03 rs2198337 6 q q16.3 FLJ10088| 104756256 1.56E− 1.16 0.139 0.123 A (SEQ ID NO: 0580) HACE1 03 ctgtcttcattcctcc[A/G] gctactatccctaccc 03 rs9386412 6 q q16.3 FLJ10088| 104760556 7.99E− 1.17 0.139 0.122 A (SEQ ID NO: 0581) HACE1 04 tactgccaaacctcca[A/C] tcaaaatagctagggc 03 rs6918769 6 q q16.3 FLJ10088| 104952471 2.49E− 1.17 0.100 0.087 A (SEQ ID NO: 0582) HACE1 03 ctgtctgctaggagta[A/G] catcaggaagtgtctg 03 rs404900 6 q q16.3 FLJ10088| 104765922 7.45E− 1.16 0.145 0.127 C (SEQ ID NO: 0583) HACE1 04 accctagatctttctc[A/C] ttctcttcatacacat 02 rs2852525 6 q q16.3 GRIK2 101875714 1.52E− 0.88 0.433 0.466 C (SEQ ID NO: 0584) 05 attgctagcatttatt[A/C] agtgaatgaataaatg 03 rs7759938 6 q q16.3 HACE1| 105378954 8.66E− 0.91 0.302 0.323 G (SEQ ID NO: 0585) LOC 05 agcctcaaaggtagca[A/G] 100129852 cctttagaaagaaaaa 03 rs314286 6 q q16.3 LIN28B 105436053 3.63E− 0.89 0.309 0.335 G (SEQ ID NO: 0586) 04 aaaaactctgtagcta[A/G] tatcatgcttaatgat 03 rs369065 6 q q16.3 LIN28B 105444058 6.34E− 0.89 0.314 0.339 G (SEQ ID NO: 0587) 04 tttctgatggcatcca[A/G] tccagagcaaatccct 03 rs314272 6 q q16.3 LIN28B 105462004 7.45E− 0.90 0.417 0.443 G (SEQ ID NO: 0588) 04 tagtttgaaaccctat[A/G] atgttctttgaaacct 03 rs453530 6 q q16.3 LOC 100829135 1.39E− 1.34 0.031 0.024 A (SEQ ID NO: 0589) 100287035| 03 agagcatcctaaatcc[A/G] SIM1 actcttaggggaagac 03 rs7769704 6 q q22.31 PKIB 122998592 8.72E− 0.92 0.321 0.340 G (SEQ ID NO: 0590) 03 ctgtgctgcttaccat[A/G] tatggatgaggggttg 02 rs7774820 6 q q22.31 TRDN 123955723 2.22E− 1.16 0.051 0.045 G (SEQ ID NO: 0591) 05 aaaagactggaggaag[A/G] caattgtagctagggc 03 rs3757169 6 q q23.3 MAP3K5| 137142946 1.24E− 1.11 0.434 0.409 G (SEQ ID NO: 0592) PEX7 03 ggtatatggttaagat[A/G] atcatacgacttggtt 03 rs899894 6 q q23.3 PDE7B 136392020 1.13E− 1.11 0.409 0.385 G (SEQ ID NO: 0593) 03 tcaattgttcatttgg[A/G] caagagtttgggtttg 03 rs1013020 6 q q23.3 PDE7B 136394895 1.00E− 1.11 0.412 0.387 A (SEQ ID NO: 0594) 03 tccagatttttactat[A/G] tgtggctgtaaaaatg 03 rs844562 6 q q24.3 SAMD5| 147908995 9.13E− 1.11 0.438 0.413 A (SEQ ID NO: 0595) SASH1 05 taaacttagacatgaa[A/G] tagagaaaggaggtta 03 rs2294806 6 q q24.3 SAMD5| 148183190 1.94E− 1.13 0.381 0.353 G (SEQ ID NO: 0596) SASH1 04 ataaaggaaggtaaaa[A/G] ctcagaaggccaaagg 03 rs6924763 6 q q24.3 STXBP5 147685480 3.09E− 1.13 0.173 0.156 A (SEQ ID NO: 0597) 03 catgattaaaagtatc[A/G] tcttcagacatctgct 03 rs12201953 6 q q25.1 UST| 149546620 4.05E− 1.30 0.032 0.025 A (SEQ ID NO: 0598) MAP3K7IP2 03 gcctggtattccatgg[A/G] tcatgtcaaaaaacct 03 rs1544041 6 q q25.3 ARID1B 157408118 1.80E− 0.86 0.169 0.193 G (SEQ ID NO: 0599) 04 acactttaaataacgt[A/G] tccaagaaagtggaaa 02 rs240863 6 q q25.3 FNDC1| 159915825 1.87E− 1.21 0.149 0.127 A (SEQ ID NO: 0600) SOD2 05 tggtcattcgaccttc[A/G] ccccataaatagtggt 03 rs2201886 6 q q25.3 NOX3| 155999177 1.87E− 0.89 0.378 0.407 A (SEQ ID NO: 0601) ARID1B 04 ggccaatctaacacaa[A/G] catgactagtgggttc 03 rs7739122 6 q q25.3 NOX3| 155998741 7.46E− 1.10 0.319 0.298 G (SEQ ID NO: 0602) ARID1B 05 tatggtctgctgagtc[A/G] ataatctatgttttta 03 rs6913088 6 q q25.3 NOX3| 155970936 3.43E− 1.10 0.512 0.488 G (SEQ ID NO: 0603) ARID1B 03 ctgtgtataattcaaa[A/G] catctccttttttgtt 02 rs9397831 6 q q25.3 NOX3| 155994436 3.48E− 1.12 0.419 0.393 G (SEQ ID NO: 0604) ARID1B 06 aacaatcacaattttc[A/G] ttgatttatctcccca 03 rs16892910 6 q q26 PARK2 162096342 1.20E− 1.11 0.169 0.155 A (SEQ ID NO: 0605) 02 gataccttatgtgacc[A/G] tagttagtcggtgatc 02 rs4710698 6 q q27 C6orf208| 170439874 2.24E− 1.12 0.414 0.386 A (SEQ ID NO: 0606) LOC154449 05 ttaaatatctaaatgt[A/G] taaaacagacctgatc 02 rs4710879 6 q q27 C6orf208| 170426027 4.60E− 1.12 0.415 0.389 G (SEQ ID NO: 0607) LOC154449 05 cgacaaggctgggatc[A/G] gtgctctccttccagc 03 rs4710811 6 q q27 C6orf208| 170369459 1.02E− 1.17 0.182 0.160 A (SEQ ID NO: 0608) LOC154449 04 caattcattctgtgcc[A/G] actcacccctggggtc 03 rs698626 7 p p11.2 LOC389493|  56282855 1.27E− 0.92 0.454 0.474 A (SEQ ID NO: 0609) LOC441228 02 gtctagcaatccttgt[A/G] tatgctttaatcacag 03 rs9690458 7 p p12.1 DKFZp564  53360479 1.32E− 1.20 0.082 0.070 G (SEQ ID NO: 0610) N2472| 03 caggtttagtttgaga[A/G] FLJ45974 ccagcaaactgaaaag 02 rs4326334 7 p p12.1 LOC  52996013 1.19E− 0.87 0.411 0.445 G (SEQ ID NO: 0611) 100131871| 05 ggaagtcaattaaaaa[A/G] DKFZp564 tctaaatataaatttg N2472 02 rs1358603 7 p p12.1 LOC  52757480 5.71E− 1.14 0.501 0.469 A (SEQ ID NO: 0612) 100131871| 05 gaatttaaaaatatca[A/G] DKFZp564 tacaagaaagtcatta N2472 03 rs6967460 7 p p12.1 LOC  52950472 3.33E− 1.25 0.068 0.055 G (SEQ ID NO: 0613) 100131871| 04 ttagcatgagccacag[A/G] DKFZp564 aaaggtttttgagcca N2472 01 exm2264261 7 p p12.3 TNS3|  47641920 4.47E− Inf 0.011 0.001 C (SEQ ID NO: 0614) C7orf65 11 agtttctgtgttttaa[A/C] ggaatagcctgctgtg 03 rs1434960 7 p p13 DDX56  44612992 3.58E− 1.38 0.032 0.023 G (SEQ ID NO: 0615) 04 gtccggccctgctacc[A/G] ccaacctttgcgtaat 03 rs11535191 7 p p14.1 ELMO1|  37747276 1.18E− 0.87 0.171 0.191 G (SEQ ID NO: 0616) GPR141 03 aagtaaattgcccaag[A/G] tggcccagctagtaaa 03 rs1364729 7 p p14.1 ELMO1|  37618173 1.26E− 0.87 0.163 0.182 G (SEQ ID NO: 0617) GPR141 03 tgtctgtctctaaatc[A/G] tgtgctgttaaaaaat 03 rs3801216 7 p p14.1 GLI3  42233283 1.54E− 1.13 0.403 0.374 A (SEQ ID NO: 0618) 04 gctcctttttaactca[A/G] tattacctgtggtttt 03 rs2392465 7 p p14.2 AOAH|  36800555 4.78E− 0.92 0.446 0.468 A (SEQ ID NO: 0619) ELMO1 03 tggggggtccatgtgg[A/G] aaagactgtgagtggc 03 rs10488088 7 p p14.3 C7orf41  30182813 5.48E− 0.85 0.117 0.135 G (SEQ ID NO: 0620) 04 tgttttatctgtggac[A/G] ctacctcgtgagattg 02 rs2270221 7 p p14.3 PDE1C  31904027 5.19E− 1.20 0.302 0.266 A (SEQ ID NO: 0621) 07 ttccttgcttcttttg[A/G] cccaacattttagcgc 03 rs38523 7 p p15.1 JAZF1|  28039797 1.38E− 0.92 0.350 0.368 G (SEQ ID NO: 0622) LOC 02 ttctgaagtatctcta[A/G] 100128081 aaagtgtctctataaa 03 rs6949451 7 p p15.2 HOXA10  27215041 1.84E− 1.12 0.493 0.464 A (SEQ ID NO: 0623) 04 gactgccctagctgag[A/G] gtatgggagggagggg 02 rs11773804 7 p p15.2 LOC  27206688 1.84E− 1.15 0.444 0.411 C (SEQ ID NO: 0624) 100289444 05 tgattacccctgttct[A/C] ggagtcgctgctttct 03 rs7795246 7 p p15.3 CDCA7L|  22047162 7.08E− 1.09 0.489 0.468 A (SEQ ID NO: 0625) RAPGEF5 03 gaattgactactgcaa[A/C] tgtgcatgattttatc 03 rs2285942 7 p p15.3 DNAH11  21582917 6.99E− 0.92 0.134 0.144 A (SEQ ID NO: 0626) 02 ccgaggttaggcgaag[A/G] gtcggggcttctctga 03 rs12534005 7 p p15.3 IGF2BP3  23502518 6.44E− 0.85 0.122 0.141 G (SEQ ID NO: 0627) 04 gatggcaagcatacat[A/G] gttttgagtgttccat 02 rs11772760 7 p p15.3 RAPGEF5  22246644 1.88E− 1.15 0.357 0.326 G (SEQ ID NO: 0628) 05 gtagttgaatatttgc[A/G] acttatatcaacctat 02 rs6461639 7 p p15.3 RAPGEF5  22186955 2.47E− 1.12 0.382 0.356 A (SEQ ID NO: 0629) 05 tgatttcggggctttc[A/G] ctttcattatgctgtc 03 rs2723512 7 p p21.1 AHR|  17815402 7.51E− 1.19 0.133 0.114 A (SEQ ID NO: 0630) SNX13 05 tgagtcaacatgaagt[A/G] agggaaatgaaaaggg 03 rs697521 7 p p21.1 BZW2|  16764156 7.81E− 1.18 0.116 0.100 A (SEQ ID NO: 0631) TSPAN13 04 ctactgcttacttctg[A/C] ctccatgtagaataaa 03 rs17437739 7 p p21.1 FERD3L|  19437424 1.41E− 1.11 0.457 0.432 A (SEQ ID NO: 0632) TWISTNB 03 aaaggagcattcacac[A/C] gcttctcttgtcatga 03 rs4286843 7 p p21.1 FERD3L|  19463247 9.35E− 1.09 0.484 0.464 A (SEQ ID NO: 0633) TWISTNB 03 ggcagaacttttattg[A/G] ctaggagtttcttttt 03 rs9648255 7 p p21.1 FERD3L|  19450683 1.38E− 0.93 0.465 0.484 G (SEQ ID NO: 0634) TWISTNB 02 gtgagcacatgcctct[A/G] taagtgattttaaaat 03 rs6461452 7 p p21.1 FERD3L|  19691229 7.69E− 1.11 0.316 0.294 A (SEQ ID NO: 0635) TWISTNB 05 aagagccagggttgac[A/G] gctctcagagagaaga 03 rs17140423 7 p p21.1 HDAC9  19007884 2.44E− 1.13 0.314 0.288 G (SEQ ID NO: 0636) 04 gaatgtttgaacatct[A/G] tagtaatattgaacca 03 rs6955426 7 p p21.2 DGKB  14310702 1.05E− 1.12 0.138 0.124 A (SEQ ID NO: 0637) 02 ttctacagaaatacaa[A/G] ctgtcttatgagtaaa 03 rs17614094 7 p p21.3 PHF14|  11328154 2.72E− 1.19 0.133 0.115 A (SEQ ID NO: 0638) THSD7A 04 agaagtaaaacagttc[A/G] tataaaagtgaatttt 03 rs10261632 7 p p21.3 PHF14|  11383722 1.79E− 1.13 0.402 0.373 A (SEQ ID NO: 0639) THSD7A 04 gaaaggaggaatttct[A/G] tttcaagcgacaccgt 02 rs2895215 7 p p22.3 ELFN1|   1837636 2.11E− 1.16 0.251 0.224 A (SEQ ID NO: 0640) MAD1L1 05 ttagtatattgtatcc[A/G] gtgaatttcgctaaat 03 rs160646 7 q q11.21 ASL  65556280 1.98E− 1.19 0.126 0.107 A (SEQ ID NO: 0641) 04 ctgggattacaagcat[A/G] agccaccaggcctagc 03 rs419603 7 q q11.21 CRCP  65597341 2.04E− 1.19 0.126 0.108 A (SEQ ID NO: 0642) 04 actttggaagtgtcaa[A/G] gtcatggaagacaaag 03 rs2243480 7 q q11.21 CRCP  65599196 2.24E− 1.19 0.126 0.108 A (SEQ ID NO: 0643) 04 tttaattacagtcatt[A/G] cctttgttttttctca 02 rs1039664 7 q q11.21 GUSB|ASL  65449716 7.60E− 1.21 0.124 0.104 C (SEQ ID NO: 0644) 05 atgaaaataaaaaaac[A/C] atgtaaacatttggga 03 rs1267818 7 q q11.21 KCTD7  66107024 3.02E− 1.19 0.125 0.108 A (SEQ ID NO: 0645) 04 tgataactactggccc[A/G] tctcaaggcaagatga 03 rs1267817 7 q q11.21 KCTD7|  66110040 3.00E− 1.19 0.125 0.108 A (SEQ ID NO: 0646) LOC 04 tgagtcccaagccagg[A/C] 100289135 acatggcatcccctga 02 rs6460260 7 q q11.21 L0C  65215455 4.87E− 1.22 0.124 0.104 A (SEQ ID NO: 0647) 100131973 05 atgctgctgaggccct[A/G] ggcttctatggtagat 03 rs2178742 7 q q11.21 LOC  66197799 1.84E− 1.20 0.126 0.107 A (SEQ ID NO: 0648) 100289135| 04 tctcgcttttgctctc[A/G] RABGEF1 ctctcactctgtagcc 03 rs35315599 7 q q11.21 RABGEF1  66254767 1.56E− 1.20 0.126 0.108 A (SEQ ID NO: 0649) 04 atttaagtttcccctc[A/G] cctatcactatgtgct 02 rs35391607 7 q q11.21 VKORC1L1  65360829 7.76E− 1.21 0.124 0.105 A (SEQ ID NO: 0650) 05 tagtaaatggtattgg[A/G] tgaactgagtagccat 02 rs6949812 7 q q11.21 VKORC1L1  65387101 8.77E− 1.21 0.124 0.105 A (SEQ ID NO: 0651) 05 ttcatttaccaatcac[A/G] taccttttttgtcatt 03 rs11983901 7 q q11.22 STAG3L4|  68571255 6.12E− 0.82 0.050 0.060 C (SEQ ID NO: 0652) AUTS2 03 tattggttcagccctg[A/C] aacacaggccatcttg 03 rs5745774 7 q q21.11 LOC  81330627 2.04E− 1.17 0.057 0.049 A (SEQ ID NO: 0653) 100128317| 02 ggaaagaaactagttt[A/G] HGF tctcaactctgtattc 03 rs17166931 7 q q21.13 C7orf62|  88760129 1.81E− 1.41 0.032 0.023 A (SEQ ID NO: 0654) ZNF804B 04 gatcttctctaccttg[A/G] tataaaaatcacctca 03 rs10255948 7 q q21.13 ZNF804B|  89536358 2.57E− 1.10 0.449 0.425 A (SEQ ID NO: 0655) DPY19L2P4 03 ttggttaatttgaact[A/C] ttccctctgatatatt 03 rs4466326 7 q q21.13 ZNF804B|  89645073 3.30E− 0.89 0.373 0.401 A (SEQ ID NO: 0656) DPY19L2P4 04 ataccaggccatactt[A/G] gccatcaaaagtttga 03 rs2214213 7 q q21.3 CALCR  93078060 3.44E− 1.10 0.445 0.423 A (SEQ ID NO: 0657) 03 tgctaatctgttcctt[A/G] taaattttcacacaaa 03 rs2240293 7 q q21.3 LOC402679  96622720 1.19E− 0.90 0.460 0.485 G (SEQ ID NO: 0658) 03 gcggccggccgccaat[A/G] gaatcttgctcctact 03 rs10282336 7 q q21.3 OCM2|LMTK2  97731700 2.78E− 1.26 0.065 0.052 A (SEQ ID NO: 0659) 04 tattttcaacaaacag[A/G] ataggactattttcac 03 rs12532957 7 q q21.3 SLC25A13  95805504 1.14E− 1.26 0.051 0.041 A (SEQ ID NO: 0660) 03 agagagtctaggtgag[A/G] cacttcatcacaacca 03 rs4727590 7 q q22.2 ORC5L| 103879276 1.50E− 1.15 0.144 0.128 G (SEQ ID NO: 0661) LHFPL3 03 tctctctcaaaatcat[A/G] cacttctttccactac 03 rs212438 7 q q22.3 ATXN7L1| 105528339 2.50E− 1.13 0.204 0.185 G (SEQ ID NO: 0662) FLJ23834 03 atctgatgtgcaggta[A/G] gaaatgtcacaggagg 02 rs2111201 7 q q31.1 NRCAM 107965942 2.99E− 1.13 0.316 0.291 A (SEQ ID NO: 0663) 05 tgagggggaaagcaac[A/G] tagatactgggaacaa 03 rs4142284 7 q q31.1 NRCAM 107940173 5.92E− 1.12 0.315 0.290 A (SEQ ID NO: 0664) 05 ttctggtcaatgtgct[A/G] tatgtacatgacaaat 03 rs2267887 7 q q31.1 NRCAM 107968803 3.06E− 1.12 0.423 0.395 G (SEQ ID NO: 0665) 04 ggaggaacaaaaacca[A/G] ccagtctctggactgt 02 rs10215206 7 q q31.1 PNPLA8 108117088 2.07E− 1.18 0.205 0.179 A (SEQ ID NO: 0666) 05 caatttcatttccttc[A/G] gacatatacccggagt 03 rs10249427 7 q q31.1 PNPLA8 108116481 3.62E− 1.15 0.200 0.178 G (SEQ ID NO: 0667) 04 taagaaaaggaatgag[A/G] aaacttgattggtgta 03 rs40851 7 q q31.1 PNPLA8 108145121 1.08E− 0.90 0.385 0.410 A (SEQ ID NO: 0668) 03 ccatgccaacaacatt[A/G] agaagaacaaggttgg 03 rs3823855 7 q q31.32 CADPS2 122057923 7.65E− 1.12 0.318 0.294 A (SEQ ID NO: 0669) 04 ttagagaagaaatact[A/G] tatgacacagatgagg 03 rs1582258 7 q q31.33 GRM8 126122354 1.22E− 0.92 0.352 0.371 G (SEQ ID NO: 0670) 02 gcaattccacttctgg[A/G] tatatgccacaaagta 02 exm657854 7 q q32.2 CPA1 130023245 1.18E− 47.2 0.005 0.000 A (SEQ ID NO: 0671) 11 9 cagttcagcacggggg[A/G] cagtaagcgtccagcc 02 rs13234407 7 q q32.3 KLF14| 130438214 4.72E− 0.89 0.461 0.491 A (SEQ ID NO: 0672) FLJ43663 05 gaatctgttactctgg[A/G] acacagatgcagggtt 03 rs7795357 7 q q32.3 KLF14| 130458874 2.68E− 1.22 0.058 0.048 G (SEQ ID NO: 0673) FLJ43663 03 cccagcagcttacacc[A/G] cacctccctgttacat 02 rs157950 7 q q32.3 L0C 130601205 9.29E− 1.26 0.075 0.060 G (SEQ ID NO: 0674) 100506860 03 aatgaagattcaggac[A/G] acgaagcagtggtaac 03 rs13228664 7 q q32.3 MKLN1 131132340 4.56E− 0.91 0.442 0.464 G (SEQ ID NO: 0675) 03 gtaatactccttctac[A/G] atcctaagatgggtct 03 rs4725613 7 q q34 CLCN1 143025985 1.63E− 1.10 0.474 0.450 G (SEQ ID NO: 0676) 03 gaatgtctattctctg[A/G] atgagcaggggaggag 03 rs6973542 7 q q35 CNTNAP2 147029028 3.45E− 0.91 0.399 0.422 G (SEQ ID NO: 0677) 03 atggtcagctggcttt[A/G] ctgttcacaacatgtt 02 exm2262270 7 q q36.1 FABP5P3| 152211627 4.47E− Inf 0.010 0.002 A (SEQ ID NO: 0678) XRCC2 11 tttccagtcttatttc[A/C] ggggctggcggtggta 02 exm674318 7 q q36.1 MLL3 151882672 4.52E− 3.24 0.026 0.008 A (SEQ ID NO: 0679) 15 ctttcttgtgagcttg[A/C] ttttctccacaatttg 03 rs4609156 8 p p12 LOC642513|  31133658 2.74E− 1.10 0.478 0.454 G (SEQ ID NO: 0680) NRG1 03 tcctgaaaaggtctca[A/G] ttctcatcagccagcg 03 rs16879927 8 p p12 NRG1  32612705 4.22E− 0.82 0.088 0.105 G (SEQ ID NO: 0681) 04 accaaacttcaagacc[A/G] aacatagggaacccaa 03 rs17671468 8 p p12 NRG1|  32633362 7.92E− 0.83 0.089 0.105 A (SEQ ID NO: 0682) FUT10 04 ctatttgcaagggaga[A/G] gaagggcacctaatat 03 rs4732639 8 p p21.2 DPYSL2|  26605110 8.05E− 1.12 0.305 0.282 G (SEQ ID NO: 0683) ADRA1A 04 gaagagcaccacttag[A/G] cacttcagagacccat 03 rs7826422 8 p p21.2 DPYSL2|  26602648 2.88E− 1.25 0.073 0.059 A (SEQ ID NO: 0684) ADRA1A 04 tgaaccaggaaactga[A/G] ggctcttgtggtccag 03 rs10503799 8 p p21.2 DPYSL2|  26605624 2.69E− 1.25 0.073 0.059 A (SEQ ID NO: 0685) ADRA1A 04 ctaccccttcaacagc[A/G] atttactacttgatcc 03 rs7013854 8 p p21.2 EBF2  25733066 1.20E− 1.17 0.185 0.163 G (SEQ ID NO: 0686) 04 cttgaattctttagaa[A/G] tcatagaaattatcct 03 rs920300 8 p p21.2 NKX3-1|  23554565 2.33E− 1.11 0.266 0.246 G (SEQ ID NO: 0687) NKX2-6 03 ggctccctgtcctttc[A/G] cccctcggttccttcc 03 rs12543268 8 p p21.2 NKX3-1|  23556615 6.68E− 0.90 0.358 0.383 A (SEQ ID NO: 0688) NKX2-6 05 gagagattacggagac[A/G] gaagacaggcagctgg 03 rs977262 8 p p21.3 LOC  19081781 7.08E− 1.12 0.301 0.277 G (SEQ ID NO: 0689) 100128993| 04 atgaaagatgagggga[A/G] SH2D4A agagagatgtgcaaaa 03 rs7012411 8 p p22 TUSC3|  15788332 1.41E− 0.90 0.470 0.496 A (SEQ ID NO: 0690) MSR1 03 tgcaattcatccacac[A/C] ctgaaagatcctgtta 03 rs2980418 8 p p23.1 FLJ10661|   8114228 3.75E− 1.09 0.194 0.181 G (SEQ ID NO: 0691) PRAGMIN 02 tgcacctttgttaaaa[A/G] acaaatgactgtatgt 03 rs7014329 8 p p23.1 LOC340357  12626394 5.44E− 0.94 0.478 0.493 A (SEQ ID NO: 0692) 02 catgctgcccttttct[A/G] ctgtctcaaacttgat 03 rs7011215 8 p p23.1 MSRA|  10312694 5.53E− 1.13 0.359 0.332 G (SEQ ID NO: 0693) LOC346702 05 cctgaacattataaac[A/G] agacaagtataaacag 03 rs7816211 8 p p23.2 CSMD1   3980317 7.75E− 1.10 0.235 0.218 G (SEQ ID NO: 0694) 03 tcactgtcttccatca[A/G] aaaaacaaatgattta 03 rs2617009 8 p p23.2 CSMD1   4496463 2.32E− 0.92 0.202 0.217 A (SEQ ID NO: 0695) 02 agggttctattctttc[A/G] aactactccagcagtc 03 rs4523281 8 p p23.2 CSMD1   3496633 1.28E− 1.33 0.049 0.038 A (SEQ ID NO: 0696) 04 aatcttttgctagaat[A/G] aagtcctttgcatttt 02 exm678864 8 p p23.2 CSMD1   3216809 1.26E− Inf 0.003 0.000 G (SEQ ID NO: 0697) 07 tgccttcagccgaaga[A/G] ttggttttcactttgg 03 rs2724974 8 p p23.2 CSMD1   4494520 4.03E− 0.90 0.224 0.244 G (SEQ ID NO: 0698) 03 gaatgcccttttttca[A/G] tcctccgtgtgattgg 03 rs17071029 8 p p23.2 CSMD1   4536253 2.02E− 1.14 0.166 0.148 A (SEQ ID NO: 0699) 03 ctgttgttaaacacat[A/G] tgctaatttcaaaata 03 rs17073854 8 p p23.2 CSMD1|   5377735 7.16E− 1.16 0.095 0.083 A (SEQ ID NO: 0700) LOC 03 aggaggtttgtctttg[A/G] 100287015 ttcgcctgcaccttcc 03 rs6990815 8 p p23.2 CSMD1|   5713881 5.53E− 1.27 0.036 0.029 A (SEQ ID NO: 0701) LOC 03 gtggactagtgcctct[A/G] 100287015 ttttctctaatgcttt 03 rs17073881 8 p p23.2 CSMD1|   5380363 6.09E− 1.16 0.094 0.082 G (SEQ ID NO: 0702) LOC 03 tttctcagaaacctct[A/G] 100287015 aaagccatcttctgct 02 exm2173787 8 q q11.22 PXDNL  52233381 2.20E− Inf 0.003 0.000 G (SEQ ID NO: 0703) 09 gtcttctttcatccag[C/G] gctcctcggccttcct 03 rs1812576 8 q q12.2 LoC  62173034 3.45E− 1.14 0.149 0.134 G (SEQ ID NO: 0704) 100130298| 03 tccctcttcttcatac[A/G] RLBP1L1 cagccactgaatagga 03 rs1866694 8 q q12.2 LOC  62172668 1.61E− 1.13 0.209 0.189 A (SEQ ID NO: 0705) 100130298| 03 tccctccgtcatgtaa[A/C] RLBP1L1 gtaggatggcagttac 03 rs17802118 8 q q12.3 LOC  62694154 9.69E− 1.10 0.265 0.247 A (SEQ ID NO: 0706) 100287835| 03 catgagtccactggag[A/G] NKAIN3 tgttttgtagacttac 02 rs896486 8 q q12.3 NKAIN3  63415467 3.74E− 1.14 0.283 0.258 A (SEQ ID NO: 0707) 05 tacaggaccttggaaa[A/C] catgcttgaacttctt 03 rs10217013 8 q q12.3 YTHDF3|  64878574 2.00E− 1.11 0.377 0.354 A (SEQ ID NO: 0708) LOC 03 aaatgagtgaggacca[A/C] 100130155 agctgttatgtttttt 03 rs4268113 8 q q13.2 C8orf34  69509456 3.04E− 0.89 0.399 0.427 G (SEQ ID NO: 0709) 04 gcaggatacccccttg[A/G] aacaagcagcgaagat 03 rs638853 8 q q13.2 C8orf34|  70014344 5.33E− 1.13 0.150 0.135 A (SEQ ID NO: 0710) LOC 03 cacctgtgtgtatcca[A/G] 100129096 cagcaagaagactgaa 03 rs10957982 8 q q21.13 ZBTB10|  81455763 1.45E− 1.16 0.202 0.179 G (SEQ ID NO: 0711) ZNF704 04 ggtttagagtaattca[A/G] tttagctgtcatttaa 02 exm710751 8 q q22.1 INTS8  95878387 2.72E− 9.20 0.012 0.001 C (SEQ ID NO: 0712) 17 atttttgttttgtagg[A/C] gtgaactgctttcttt 03 rs16896060 8 q q22.1 MTDH  98667777 4.96E− 1.46 0.022 0.015 A (SEQ ID NO: 0713) 04 gtcctggtggtcaaaa[A/G] ggcctggacaggcatc 03 rs2618137 8 q q22.1 RUNX1T1|  93567028 2.40E− 0.78 0.039 0.050 C (SEQ ID NO: 0714) C8orf83 03 aaaagacttcttcaaa[A/C] gaaactgtgaagtctc 03 rs2704253 8 q q22.1 SDC2|PGCP  97651358 1.77E− 1.18 0.148 0.128 G (SEQ ID NO: 0715) 04 gaagaaagtttagtag[A/G] gctgaagtgtgcattt 03 rs4735529 8 q q22.2 POP1  99139610 1.84E− 0.91 0.459 0.483 G (SEQ ID NO: 0716) 03 gtaggtagcacacaag[A/G] taatcatgtcaggatg 03 rs17476650 8 q q23.2 KCNV1| 111101361 1.92E− 1.19 0.129 0.111 A (SEQ ID NO: 0717) CSMD3 04 taatagacaaatgttg[A/C] acaatagtcaaattct 03 rs7010965 8 q q23.3 CSMD3| 116299406 2.20E− 1.14 0.084 0.075 A (SEQ ID NO: 0718) TRPS1 02 tgcacatcaatctctc[A/G] tattttgcatttaaac 03 rs16887231 8 q q23.3 CSMD3| 116253370 1.32E− 1.15 0.084 0.074 G (SEQ ID NO: 0719) TRPS1 02 acctcaggaaaggatc[A/G] tggaacagggaggcct 03 rs4871240 8 q q24.13 HAS2AS| 123297701 1.02E− 0.92 0.445 0.465 G (SEQ ID NO: 0720) LOC 02 caagtttgttgcttta[A/G] 100131552 tactaccttgagtctg 02 rs13274301 8 q q24.21 PVT1 128988045 7.96E− 0.82 0.103 0.123 C (SEQ ID NO: 0721) 05 gtttcctagcttgaaa[A/C] acgaagagaagaaaag 03 rs7826937 8 q q24.21 PVT1| 129264171 1.01E− 0.92 0.345 0.365 G (SEQ ID NO: 0722) LOC 02 tgactcaccatcagga[A/G] 100287906 ggatctgctgcactgg 03 rs491614 8 q q24.22 ADCY8| 132719817 1.19E− 1.11 0.463 0.438 G (SEQ ID NO: 0723) EFR3A 03 tactgaaaaagagaat[A/G] aacaacataacagtca 03 rs581534 8 q q24.22 ADCY8| 132711614 1.67E− 1.15 0.085 0.075 G (SEQ ID NO: 0724) EFR3A 02 cttacttacctagagg[A/G] catatgtctgctactg 02 rs6999964 8 q q24.22 ADCY8| 132862920 1.68E− 1.14 0.216 0.195 A (SEQ ID NO: 0725) EFR3A 05 tataattaaggttaat[A/G] gtgagattgtttggct 02 rs4433159 8 q q24.22 ASAP1| 131571963 1.28E− 1.17 0.320 0.287 G (SEQ ID NO: 0726) ADCY8 03 ttgacttatctatgga[G/A] tttttgactatttctg 03 rs16904553 8 q q24.22 EFR3A 132947786 2.70E− 1.12 0.212 0.194 A (SEQ ID NO: 0727) 03 taacataatagaaatt[A/G] actgacatatgtatgg 03 rs6985794 8 q q24.22 LOC 134689013 9.73E− 1.08 0.129 0.121 G (SEQ ID NO: 0728) 100129104| 02 atccatagaaacagac[A/G] ZFAT ttaattaaataacaca 03 rs12548244 8 q q24.23 KHDRBS3| 137112133 7.19E− 0.90 0.368 0.395 G (SEQ ID NO: 0729) FLJ45872 04 tttcatatcagaggca[A/G] cctctcaaccagatgt 03 rs2317547 8 q q24.23 KHDRBS3| 136933622 3.97E− 1.10 0.337 0.316 C (SEQ ID NO: 0730) FLJ45872 03 tggccagaaagagaga[A/C] agagagacagagacag 03 rs10505647 8 q q24.23 KHDRBS3| 137056293 1.23E− 0.90 0.311 0.334 A (SEQ ID NO: 0731) FLJ45872 03 aaataggacccttgac[A/G] cacaaaggaattttgg 02 exm728471 8 q q24.3 EPPK1 144940658 3.25E− Inf 0.006 0.000 A (SEQ ID NO: 0732) 16 tggaagggcgtgctgc[A/G] gcccggcacggccctg 03 rs903965 8 q q24.3 FLJ43860| 142698496 1.18E− 1.44 0.020 0.014 A (SEQ ID NO: 0733) NCRNA00051 03 acacttggtacccttg[A/G] tacatttaatagtaaa 03 rs3819495 8 q q24.3 GML 143923250 1.12E− 1.16 0.085 0.075 A (SEQ ID NO: 0734) 02 ccacctgtgcgccagg[A/G] catacactggctgcac 02 rs10971957 9 p p13.3 DCAF12|  34151463 7.13E− 1.13 0.415 0.386 C (SEQ ID NO: 0735) UBAP1 03 ctatcattatcgattc[C/T] acccagcaatttctct 02 rs10972684 9 p p13.3 ORS2S|RECK  36003635 5.21E− 0.85 0.167 0.190 A (SEQ ID NO: 0736) 03 atctgctatacaacat[C/A] ctcagtccccctcatc 03 rs12726 9 p p13.3 UNC13B  35404840 4.45E− 1.13 0.263 0.240 A (SEQ ID NO: 0737) 04 gttgaaggatccagga[A/G] tattttcttcttgggt 03 rs2383733 9 p p21.2 C9orf72|  27869510 7.13E− 1.17 0.079 0.068 A (SEQ ID NO: 0738) LINGO2 03 tgtcactttcagtata[A/G] ataaaactctttagaa 03 rs10811800 9 p p21.3 DMRTA1|  22906729 2.19E− 1.10 0.420 0.396 A (SEQ ID NO: 0739) LOC402360 03 ctacattataaattat[A/G] cttgataccagacatc 03 rs 1381923 9 p p21.3 DMRTA1|  22909348 7.90E− 0.92 0.448 0.469 C (SEQ ID NO: 0740) LOC402360 03 actgatatcattccct[A/C] cctgaaatatcccatg 03 rs10116397 9 p p21.3 DMRTA1|  23570688 3.01E− 1.25 0.071 0.057 G (SEQ ID NO: 0741) LOC402360 04 ggcaaggagagcacca[A/G] tttaggaaatgttaga 03 rs2149913 9 p p21.3 ELAVL2|  24573717 6.46E− 0.89 0.318 0.343 A (SEQ ID NO: 0742) TUSC1 04 gaataagaatactaac[A/G] tttatcccctgcattt 03 rs2026590 9 p p21.3 ELAVL2|  24833789 4.21E− 1.14 0.240 0.217 A (SEQ ID NO: 0743) TUSC1 04 caatgggatttggtaa[A/C] tattttcttatctttg 03 rs11788362 9 p p21.3 ELAVL2|  24493958 1.79E− 0.89 0.216 0.237 A (SEQ ID NO: 0744) TUSC1 03 aaaaaagtactaattc[A/G] gaaaagatataaaagt 03 rs10511626 9 p p22.2 BNC2  16764989 3.61E− 0.90 0.110 0.120 A (SEQ ID NO: 0745) 02 atcagagtatatgcca[A/C] agcgggtttcgtatcc 02 rs1442514 9 p p22.2 CNTLN  17419319 3.13E− 1.25 0.094 0.076 A (SEQ ID NO: 0746) 05 tactaagcattattct[A/G] tagatggaatatataa 03 rs2772695 9 p p22.2 SH3GL2|  17985166 4.54E− 1.13 0.166 0.150 A (SEQ ID NO: 0747) ADAMTSL1 03 gagacttcactctgac[A/G] tctttctctttttgga 03 rs10810211 9 p p22.3 ZDHHC2|  14676870 1.30E− 1.23 0.037 0.030 G (SEQ ID NO: 0748) 02 caagtgctctctcaac[A/G] tgttcaatattactaa 02 rs12236892 9 p p24.1 C9orf123|   7834442 5.91E− 1.30 0.063 0.050 G (SEQ ID NO: 0749) PTPRD 05 gtttctaaatatgtca[A/G] agtagatattaaagaa 02 exm737779 9 p p24.1 ERMP1   5832719 4.28E− 4.87 0.028 0.006 G (SEQ ID NO: 0750) 24 gcggggccgctggaca[C/G] cgcggggagttcgacg 02 rs10975519 9 p p24.1 IL33   6253571 6.06E− 1.18 0.338 0.302 A (SEQ ID NO: 0751) 07 ggtgttgagactcata[A/G] taactcagtaacacct 01 rs1332290 9 p p24.1 IL33   6255881 6.96E− 1.17 0.391 0.354 A (SEQ ID NO: 0752) 07 tggaaactaaagggga[A/C] tacttatttatgactt 02 rs10975516 9 p p24.1 IL33   6247693 2.31E− 1.15 0.335 0.304 A (SEQ ID NO: 0753) 05 ctttgaccccagtgga[A/G] tgctctctcctgcaaa 01 rs1048274 9 p p24.1 IL33   6256292 3.99E− 1.17 0.333 0.300 A (SEQ ID NO: 0754) 06 ttagcatgtgtggaat[A/G] ttttccatattatgta 01 rs1330383 9 p p24.1 IL33   6251507 4.64E− 1.17 0.333 0.300 A (SEQ ID NO: 0755) 06 accatgggattccaat[A/C] cattgcaagtatttca 02 rs10815398 9 p p24.1 IL33|   6272766 6.98E− 1.16 0.393 0.359 C (SEQ ID NO: 0756) LOC645969 06 gcagtctctcccttga[A/C] acatccttccccttcc 02 rs10815402 9 p p24.1 LOC645969|   6293715 5.40E− 1.17 0.305 0.273 A (SEQ ID NO: 0757) TPD52L3 06 tccagacacaagtcac[A/G] agttcaggggttcaca 03 rs10975539 9 p p24.1 LOC645969|   6308729 9.21E− 0.88 0.213 0.235 A (SEQ ID NO: 0758) TPD52L3 04 cccccaataacaggaa[A/G] gagattcctttgttcc 03 rs12551256 9 p p24.1 RANBP6|   6231239 1.64E− 1.13 0.491 0.462 G (SEQ ID NO: 0759) IL33 04 cttctttggcttctca[A/G] tgcactctgaatgaaa 02 rs1052335 9 p p24.1 TPD52L3   6330380 2.74E− 1.19 0.220 0.192 C (SEQ ID NO: 0760) 05 cactgcctgagataga[A/C] gtttgcatcttattgg 03 rs4741806 9 p p24.2 KIAA0020|   3099009 1.23E− 0.82 0.074 0.088 C (SEQ ID NO: 0761) RFX3 03 tttttcttattgattc[A/C] taggagttctttacat 02 rs7021672 9 p p24.2 KIAA0020|   3097453 9.19E− 0.86 0.205 0.231 A (SEQ ID NO: 0762) RFX3 05 tttattgatagtttac[A/G] ctgctggaaatataat 03 rs2986687 9 p p24.2 RFX3   3301887 5.31E− 1.19 0.124 0.106 A (SEQ ID NO: 0763) 05 agacctgaagagcagg[A/G] accctggtggattttt 03 rs3012708 9 p p24.2 RFX3   3322283 1.71E− 1.14 0.184 0.165 G (SEQ ID NO: 0764) 03 tcaagtttccttttgt[A/G] tccctggcgaacttta 03 rs7868484 9 p p24.3 SMARCA2   2141357 7.19E− 1.14 0.300 0.273 A (SEQ ID NO: 0765) 05 tatggtttttggattt[A/C] gcatttagttaatgac 02 rs10746847 9 q q21.12 TRPM3  73170382 3.23E− 0.89 0.416 0.446 G (SEQ ID NO: 0766) 05 tcctgtacaggtgcat[A/G] tggatgtgctatgtgt 03 rs10746850 9 q q21.12 TRPM3  73183281 7.86E− 0.90 0.443 0.469 G (SEQ ID NO: 0767) 05 aaattctatgccaagc[A/G] ctttcatatacaatat 02 rs3739776 9 q q21.12 TRPM3  73151970 1.35E− 0.88 0.414 0.445 G (SEQ ID NO: 0768) 05 gccattctttctattc[A/G] gtcaatatgaaagaca 02 rs6560143 9 q q21.12 TRPM3  73168680 4.19E− 0.89 0.415 0.444 G (SEQ ID NO: 0769) 05 cctgttgttaattccc[A/G] atcaatagtcccgaga 03 rs10119759 9 q q21.31 PSAT1  82018583 6.22E− 0.94 0.305 0.319 C (SEQ ID NO: 0770) TLE4| 02 gctccagggctgggac[A/C] ctttctgagcctcctc 03 rs9314677 9 q q21.31 PSAT1  82018917 3.29E− 1.10 0.347 0.325 G (SEQ ID NO: 0771) TLE4| 03 gatgtaggtaaccatc[A/G] ttatgggaccccagag 03 rs2378380 9 q q21.31 PSAT1|  82032456 3.22E− 0.93 0.300 0.316 A (SEQ ID NO: 0772) TLE4 02 gcaacaggggtactag[A/G] gcatcatgaaattcac 03 rs3897745 9 q q21.32 TLE1  84215944 1.22E− 0.88 0.182 0.202 A (SEQ ID NO: 0773) 03 ctacacagtcgtgtga[A/G] ccaatccctccaaata 03 rs9410282 9 q q22.1 LOC286238|  91318984 3.33E− 0.89 0.418 0.446 A (SEQ ID NO: 0774) C9orf47 04 aggctctgtgatgggc[A/G] caggaacacactgagg 02 rs944485 9 q q22.1 SHC3  91679818 4.83E− 1.17 0.411 0.374 T (SEQ ID NO: 0775) 04 ttgtgccgttattaat[T/G] ccatttgttatttcat 02 exm764237 9 q q22.32 C9orf102  98684662 4.73E− 189 0.004 0.000 A (SEQ ID NO: 0776) 08 0 gcttgcagtagcgcga[A/C] atggttagctaccttc 02 exm768001 9 q q31.1 GRIN3A 104335619 4.40E− 3.17 0.017 0.005 G (SEQ ID NO: 0777) 10 gccttgcggaccacca[A/G] tgggaaagcagactcc 03 rs698459 9 q q31.1 LOC347281 107234158 1.22E− 0.89 0.282 0.306 C (SEQ ID NO: 0778) OR13F1| 03 cttgatgtgtcaggac[A/C] attttgttgctgtagg 03 rs2808374 9 q q31.2 LOC 109987079 4.12E− 1.11 0.280 0.260 G (SEQ ID NO: 0779) 100128086| 03 ctcgctactgatggac[A/G] RAD23B ttcacatttaaatttt 03 rs7864733 9 q q31.2 LOC644620 109427261 9.34E− 0.92 0.474 0.494 C (SEQ ID NO: 0780) 03 actgaaatatagccag[A/C] aataaataatcatgct 03 rs16934033 9 q q33.1 ASTN2 119657927 2.09E− 1.55 0.019 0.012 A (SEQ ID NO: 0781) 04 ctcctatattcaacag[A/G] acagcaaatgaagact 03 rs1990422 9 q q33.1 DBC1| 122244046 5.73E− 1.15 0.240 0.216 G (SEQ ID NO: 0782) CDK5RAP2 05 atgaaaatataaaatc[A/G] attgtggtgatggttt 02 rs10513376 9 q q33.2 DAB2IP 124354826 3.47E− 0.84 0.294 0.331 C (SEQ ID NO: 0783) 04 agctcagaaaatctca[T/C] tggaacccttgaagta 02 rs10985200 9 q q33.2 GSN 124043867 5.48E− 1.14 0.497 0.465 A (SEQ ID NO: 0784) 05 cggggtttaagaggac[A/G] acaggtgtctgtattg 03 rs3810942 9 q q33.2 GSN| 124044995 1.76E− 1.13 0.490 0.461 A (SEQ ID NO: 0785) LOC 04 atcagagccaagaccc[A/G] 100128064 gccctcaagtcctcct 03 rs10156486 9 q q33.2 LOC729012| 125538981 5.27E− 0.65 0.010 0.016 C (SEQ ID NO: 0786) OR5C1 03 tgtggaaggggaggtc[A/C] gtcagccagcattaag 02 rs4556152 9 q q33.2 RAB14|GSN 124016909 6.03E− 1.14 0.503 0.471 A (SEQ ID NO: 0787) 05 gatttttctctcctct[A/G] aaagagcaattttctc 03 rs10760160 9 q q33.2 RAB14|GSN 124003326 3.42E− 1.12 0.490 0.462 C (SEQ ID NO: 0788) 04 acaggaaacttcaacc[A/C] agtatcaagttactaa 03 rs10760159 9 q q33.2 RAB14|GSN 123998342 2.45E− 1.12 0.489 0.460 A (SEQ ID NO: 0789) 04 cctcttcagagggaat[A/G] tggtcctgtggacacc 02 rs2239696 9 q q33.2 RAB14|GSN 124029155 2.82E− 1.14 0.502 0.469 G (SEQ ID NO: 0790) 05 ggacccagggaatctc[A/G] ccctggctcttcctcc 01 rs34250136 9 q q33.3 DENND1A| 126772954 3.07E− 1.71 0.020 0.012 A (SEQ ID NO: 0791) LHX2 06 cactgatatcgaatgt[A/G] tcttggagtgagaaag 03 rs10217721 9 q q33.3 PBX3| 128810846 2.46E− 1.07 0.455 0.437 G (SEQ ID NO: 0792) FAM125B 02 ggaattaacagccaca[A/G] tgcaagcttcttgctg 03 rs7861741 9 q q33.3 PBX3| 128810469 1.28E− 1.08 0.459 0.440 G (SEQ ID NO: 0793) FAM125B 02 ggatccatggcctggc[A/G] attccaggtctgggtt 03 rs7023572 9 q q34.13 C9orf171 135414981 5.87E− 1.05 0.356 0.344 G (SEQ ID NO: 0794) 05 tgttctagggccaacc[A/G] ggggatcggaggagtc 02 rs10508855 10 p p11.21 FZD8|  37070799 4.47E− 1.30 0.050 0.039 A (SEQ ID NO: 0795) ANKRD30A 06 gggcagagtacttatc[A/G] tatgtgcatactatat 03 rs17615892 10 p p11.21 FZD8|  36635409 3.86E− 0.89 0.172 0.190 G (SEQ ID NO: 0796) ANKRD30A 03 ctcataacattttccc[A/G] ctagaaataatgtgtg 03 rs17627587 10 p p11.21 FZD8|  36688414 1.64E− 0.87 0.143 0.161 A (SEQ ID NO: 0797) ANKRD30A 03 cttctattttgctgtt[A/G] ctgttttgcatttgag 03 rs3124188 10 p p11.23 LOC645954  30955825 2.05E− 0.89 0.232 0.253 G (SEQ ID NO: 0798) 03 atccagtgggaaagtc[A/G] gttgcatcctatgttt 03 rs17747622 10 p p12.1 ABI1  27044752 2.15E− 0.77 0.050 0.065 A (SEQ ID NO: 0799) 04 tatgtttgtggtcctt[A/G] taactgacttctgctt 03 rs10826406 10 p p12.1 MPP7  28433708 4.41E− 1.15 0.115 0.102 A (SEQ ID NO: 0800) 03 tatggaaatgatatgg[A/G] atacataggaatggcg 03 rs11006995 10 p p12.1 MPP7|  28585496 2.13E− 1.16 0.069 0.060 A (SEQ ID NO: 0801) LOC 02 aatacatagcagttgc[A/G] 100288110 atatccattttgggta 03 rs16927305 10 p p12.1 PDSS1  27023402 4.94E− 1.16 0.096 0.083 A (SEQ ID NO: 0802) 03 tgcttagcagggcact[A/G] ggaaatgcacttcagt 03 rs4748738 10 p p12.31 NEBL  21219406 2.28E− 1.11 0.350 0.328 A (SEQ ID NO: 0803) 03 ttaatttgcattttca[A/G] aaagactaccttggct 02 rs11012384 10 p p12.31 NEBL  21198380 4.04E− 1.10 0.397 0.375 G (SEQ ID NO: 0804) 02 tgcctctaagatattg[G/T] acacacaaatgaagca 03 rs17464580 10 p p12.33 STAM  17750968 9.33E− 0.79 0.051 0.064 C (SEQ ID NO: 0805) 04 actaactccaaacaag[A/C] atcaacagtaaaatta 01 rs11256106 10 p p14 GATA3|   9222228 1.98E− 1.24 0.171 0.143 C (SEQ ID NO: 0806) SFTA1P 07 tcacatatgatagatt[A/C] ggcaattgagttatat 02 rs1001019 10 p p14 GATA3|   9243785 9.54E− 1.19 0.198 0.171 A (SEQ ID NO: 0807) SFTA1P 06 gctgtttaaatgttta[A/C] ttgatgatggaatgtg 02 rs7911451 10 p p14 GATA3|   9248331 1.56E− 1.18 0.206 0.180 A (SEQ ID NO: 0808) SFTA1P 05 gtgtgtgtgaacaagc[A/G] caaagtccatatccag 03 rs2387739 10 p p14 LOC439949|   6813564 1.55E− 1.16 0.214 0.191 G (SEQ ID NO: 0809) SFMBT2 04 agtaatgccaactaca[A/G] attatgaaatatttca 02 rs11257215 10 p p14 LOC439951|  11697403 3.79E− 1.13 0.287 0.262 G (SEQ ID NO: 0810) ECHDC3 05 ggagtttccctatccc[A/G] ggctgcagtgcaatgg 03 rs4881466 10 p p15.1 CALML5|   5542109 2.16E− 1.14 0.289 0.263 A (SEQ ID NO: 0811) LOC 04 atggggctcactgcct[A/G] 100132159 taacttcaaggaagca 03 rs10904508 10 p p15.1 NET1|   5503610 4.32E− 0.89 0.298 0.324 A (SEQ ID NO: 0812) CALML5 04 ataagaaaatatccag[A/C] actgagtgtatgttta 02 rs11253141 10 p p15.1 UCN3|   5422196 5.46E− 0.88 0.361 0.392 C (SEQ ID NO: 0813) TUBAL3 05 tcaagtcatcagattg[A/C] atctccccacctgcca 03 rs2279208 10 p p15.2 PFKP   3171043 1.52E− 0.86 0.133 0.151 A (SEQ ID NO: 0814) 03 cgcccaccactgtgcc[A/G] gaatgtgatgcacaca 03 rs2388558 10 p p15.2 PITRM1   3180689 1.72E− 0.89 0.240 0.262 A (SEQ ID NO: 0815) 03 agagatcacaccccga[A/C] ctccagctcccacgtg 03 rs4881111 10 p p15.2 PITRM1   3190265 4.38E− 1.09 0.490 0.467 A (SEQ ID NO: 0816) 03 gcacaccctgaaccaa[A/G] gaaaacacagaagaaa 03 rs9423709 10 p p15.2 PITRM1   3202682 3.65E− 0.89 0.211 0.230 A (SEQ ID NO: 0817) 03 ggtccaaaaatatcac[A/G] gtacttcgagagacca 03 rs7898695 10 p p15.2 PITRM1   3184507 3.61E− 1.10 0.429 0.406 A (SEQ ID NO: 0818) 03 cacctccccatctgtg[A/G] ccctctgtgacacacg 03 rs4881109 10 p p15.2 PITRM1   3185237 1.42E− 0.89 0.233 0.255 G (SEQ ID NO: 0819) 03 acctaccatgtttatc[A/G] gaaatctcagcctaaa 03 rs4881110 10 p p15.2 PITRM1   3185393 3.57E− 0.90 0.244 0.264 G (SEQ ID NO: 0820) 03 aatgactggctctaaa[A/G] ctgggtctctgttcac 03 rs12763675 10 p p15.3 DIP2C|    744591 6.79E− 0.89 0.335 0.360 A (SEQ ID NO: 0821) LARP5 04 gcaatgtttaaaaaca[A/G] cattttgggctgggcg 03 rs12572078 10 p p15.3 NCRNA00168|   1669110 5.49E− 1.16 0.268 0.240 A (SEQ ID NO: 0822) ADARB2 05 ggtgggtgctgatgag[A/G] gaaggcaggagatgca 03 rs1875005 10 p p15.3 NCRNA00168|   1661398 8.56E− 0.90 0.450 0.476 A (SEQ ID NO: 0823) ADARB2 04 tttatctaatctgatg[A/G] tctctgctctttttat 03 rs2802477 10 q q11.21 HNRNPA3P1|  44696034 1.83E− 0.90 0.390 0.414 G (SEQ ID NO: 0824) LOC 03 cctgccgcctagggag[A/G] 100130539 ttgtgctctgcccctc 02 rs11238956 10 q q11.21 HNRNPA3P1|  44749854 1.09E− 0.87 0.316 0.348 G (SEQ ID NO: 0825) LOC 05 ccactaaaattctaca[A/G] 100130539 tcagaatgcttggcaa 03 rs268309 10 q q11.21 HNRNPA3P1|  44611148 3.62E− 1.28 0.035 0.028 A (SEQ ID NO: 0826) LOC 03 ctagaagccgaggaca[A/G] 100130539 tgagatctcttcttct 02 rs2503853 10 q q11.21 RASGEF1A|  43750260 2.57E− 1.18 0.207 0.181 A (SEQ ID NO: 0827) FXYD4 05 ccctccctttagtcag[A/G] gattattctggggacc 03 rs3844600 10 q q11.22 ARHGAP22  49683897 3.00E− 1.09 0.224 0.211 A (SEQ ID NO: 0828) 02 tgctaacagctctacc[A/G] tgatgacaaggccatt 03 rs1345107 10 q q11.22 ARHGAP22  49794481 3.07E− 1.15 0.204 0.182 A (SEQ ID NO: 0829) 04 gggttactatggtgat[A/G] aggattaggataatgg 03 rs1806437 10 q q11.22 ARHGAP22  49798463 4.29E− 0.89 0.359 0.386 A (SEQ ID NO: 0830) 04 tgcccccaccacaacc[A/G] aggacagtgtcttgcc 03 rs1881740 10 q q11.22 FRMPD2|  49551560 1.12E− 0.88 0.212 0.233 A (SEQ ID NO: 0831) MAPK8 03 ggacccagtatcttca[A/G] ggtagcatttttgaac 03 rs7898026 10 q q11.22 FRMPD2|  49497934 5.13E− 0.90 0.432 0.459 G (SEQ ID NO: 0832) MAPK8 05 ctgacagaaggactgc[A/G] gctgaatttcacattt 02 exm822086 10 q q11.22 GPRIN2  46999130 5.78E− 79.7 0.008 0.000 A (SEQ ID NO: 0833) 20 5 tggcctccagcactgg[A/G] tcgcgccttggggcca 03 rs10509234 10 q q21.3 ANXA2P3|  67473973 7.69E− 1.15 0.098 0.086 A (SEQ ID NO: 0834) CTNNA3 03 ttttttcaatgctgac[A/G] cagagtgatttaaaaa 03 rs4370822 10 q q21.3 CTNNA3  68072084 6.73E− 0.86 0.138 0.157 A (SEQ ID NO: 0835) 04 ccttgggtagctatca[A/G] gtacatgcctaacttg 02 exm833170 10 q q22.1 SPOCK2  73822855 1.96E− 17.3 0.007 0.000 A (SEQ ID NO: 0836) 13 7 gtgtgaccagagcagc[A/G] gtgactgctggtgtgt 02 exm829854 10 q q22.1 SUPV3L1  70940052 1.26E− Inf 0.003 0.000 A (SEQ ID NO: 0837) 07 tagggcacgggagaag[A/G] acatcgaggccgcagg 02 rs7081974 10 q q22.3 LOC  80215612 8.53E− 0.74 0.044 0.059 A (SEQ ID NO: 0838) 100132987 05 ggcagctagggactga[A/G] gcagcgtagcataaca 03 rs16935969 10 q q22.3 LOC  80220796 1.55E− 0.75 0.043 0.056 G (SEQ ID NO: 0839) 100132987 04 gttcgactgcaggaaa[A/G] ccctacaggttgctgg 02 rs12784427 10 q q22.3 LOC1  80207497 4.87E− 0.74 0.045 0.060 C (SEQ ID NO: 0840) 00132987 05 ctttcctggggatgct[A/C] attgaggttggaaaga 03 rs4979997 10 q q22.3 LOC  80435887 1.49E− 1.19 0.050 0.042 G (SEQ ID NO: 0841) 100132987 02 ctggttttcctaatca[A/G] LOC283050| agaaagcttcaaagaa 03 rs288444 10 q q22.3 LOC  80348121 1.30E− 0.85 0.103 0.119 G (SEQ ID NO: 0842) 100132987| 03 tattagcagactcacc[A/G] LOC283050 caaaaggatatgccag 03 rs288450 10 q q22.3 LOC  80356268 9.03E− 0.87 0.102 0.115 A (SEQ ID NO: 0843) 100132987| 03 acagcacaagaggatg[A/G] LOC283050 tgagtgggtatatagt 03 rs288447 10 q q22.3 LOC  80359650 1.12E− 0.88 0.103 0.116 A (SEQ ID NO: 0844) 100132987| 02 gaagcccaggatgaaa[A/C] LOC283050 agggttgttcaatgtc 03 rs288442 10 q q22.3 LOC  80348890 5.59E− 0.87 0.100 0.114 G (SEQ ID NO: 0845) 100132987| 03 cacagacatgcaaatt[A/G] LOC283050 ggatgtggaaccactt 02 rs1249122 10 q q22.3 RPS24|  79949403 1.28E− 0.89 0.367 0.393 T (SEQ ID NO: 0846) LOC283050 02 gggaatagatgcagaa[C/T] tggcaaagaagcaaga 03 rs703990 10 q q22.3 ZMIZ1  80930439 5.80E− 1.14 0.224 0.202 A (SEQ ID NO: 0847) 04 gcaggctttcatgtgt[A/G] ttaactattaaggctc 03 rs7906565 10 q q23.31 LOC119358|  91922383 8.31E− 0.78 0.027 0.035 G (SEQ ID NO: 0848) HTR7 03 aacaaattccatatgt[A/G] attaggatgtacatgc 02 rs6583759 10 q q23.32 NUDT9P1|  92976570 7.20E− 1.27 0.074 0.059 C (SEQ ID NO: 0849) PCGF5 05 tccccctaccattcat[A/C] catcattgattttagg 03 rs7894133 10 q q23.32 NUDT9P1|  92979176 8.65E− 1.24 0.066 0.054 A (SEQ ID NO: 0850) PCGF5 04 ttgtggtatatataca[A/G] taatatcctccaatgc 03 rs1057971 10 q q23.32 PCGF5  92987510 6.66E− 1.24 0.067 0.054 A (SEQ ID NO: 0851) 04 tggtaggggaggaagt[A/G] gtaggcagaaaccagt 03 rs7074612 10 q q23.32 PCGF5  93041869 2.55E− 1.22 0.064 0.053 G (SEQ ID NO: 0852) 03 atataaatcccataga[A/G] tgaagtcttttctata 03 rs7082510 10 q q23.32 PCGF5  93004825 9.19E− 1.23 0.067 0.055 A (SEQ ID NO: 0853) 04 ccttggtcctttactc[A/G] tgcctctctgtactca 03 rs10882232 10 q q23.33 MYOF  95189263 1.29E− 1.08 0.416 0.397 G (SEQ ID NO: 0854) 02 aagatggtataagtca[A/G] tgatttttctgccttc 02 rs2296580 10 q q24.32 ACTR1A 104241683 2.32E− 0.88 0.265 0.292 A (SEQ ID NO: 0855) 05 gcaccctgagaattga[A/C] ttgaagttctcctctt 03 rs7075281 10 q q24.32 C10orf95| 104220301 1.16E− 0.89 0.282 0.305 A (SEQ ID NO: 0856) TMEM180 03 acagcctacattgagc[A/C] aaacaaaacttgattt 03 rs7475335 10 q q24.32 SUFU 104343428 1.27E− 0.90 0.309 0.333 A (SEQ ID NO: 0857) 03 tccagcctaaataaat[A/C] cccacccggtttgggg 03 rs2236211 10 q q24.33 NEURL 105349816 3.89E− 1.10 0.421 0.399 A (SEQ ID NO: 0858) 03 ggggacacaagaggcc[A/G] gggagctctcttcccg 03 rs7071247 10 q q24.33 NEURL 105257786 1.30E− 1.19 0.151 0.130 A (SEQ ID NO: 0859) 04 agatatacgctcaagc[A/C] cctccaagcctttact 03 rs7918186 10 q q24.33 NEURL 105350447 2.46E− 1.10 0.420 0.397 A (SEQ ID NO: 0860) 03 ctagaaacctgcctca[A/G] atggggaaagattagg 03 rs729952 10 q q24.33 NEURL| 105352990 6.35E− 1.09 0.417 0.396 A (SEQ ID NO: 0861) SH3PXD2A 03 caacactgtgcctaga[A/C] cttggggccagtctgg 03 rs11191750 10 q q24.33 SH3PXD2A 105388286 2.73E− 1.17 0.174 0.153 A (SEQ ID NO: 0862) 04 ggtgcttgagccagta[A/G] ctcagaggtaacccct 03 rs7918134 10 q q24.33 SH3PXD2A 105391300 1.29E− 1.14 0.183 0.164 A (SEQ ID NO: 0863) 03 gtgattgttaggggtg[A/G] catcagcaaggactgt 02 rs11193561 10 q q25.1 SORCS1| 109374384 2.91E− 1.16 0.269 0.240 A (SEQ ID NO: 0864) LOC 05 gctgtaggcaaacagt[A/G] 100128304 aatccaatttcctcca 03 rs11195815 10 q q25.2 ADRA2A| 113859224 5.16E− 1.30 0.029 0.022 A (SEQ ID NO: 0865) GPAM 03 ctgtgctctaacactg[A/C] acattcatgtagcttt 03 rs17129504 10 q q25.2 ADRA2A| 113855817 2.88E− 1.37 0.023 0.017 C (SEQ ID NO: 0866) GPAM 03 tccaggaattcagcac[A/C] ttccagccctggagac 03 rs6584993 10 q q25.2 DUSP5| 112314670 3.83E− 1.20 0.070 0.059 A (SEQ ID NO: 0867) SMC3 03 agagaggaggggagag[A/G] taactgatacatgcta 03 rs1541466 10 q q25.3 ATRNL1 117594744 3.71E− 0.89 0.188 0.206 G (SEQ ID NO: 0868) 03 cactgtccctgaatgc[A/G] aaataagggtgacctt 03 rs2024179 10 q q25.3 ATRNL1 117591081 3.35E− 0.89 0.188 0.207 G (SEQ ID NO: 0869) 03 aagcaaaccaattgga[A/G] aggtgttccctgtatt 03 rs7099933 10 q q25.3 LOC 115728772 6.95E− 1.14 0.121 0.107 A (SEQ ID NO: 0870) 100286977| 03 ccgatagttggtgact[A/G] LOC ttttatttctttgttg 100132839 02 rs2275111 10 q q26.11 SFXN4 120917445 1.11E− 1.14 0.527 0.494 G (SEQ ID NO: 0871) 06 cagaggaaaacctgcc[A/G] agaggggcaaatggat 02 rs10749291 10 q q26.11 SFXN4 120920588 3.61E− 0.91 0.463 0.487 G (SEQ ID NO: 0872) 05 tctcctttaagataca[A/G] gaagcttggaagcgga 03 rs12355817 10 q q26.12 SEC23IP| 121838912 2.46E− 1.18 0.092 0.079 A (SEQ ID NO: 0873) PPAPDC1A 03 cccatctgtaaaatgg[A/G] cacctaccattgattc 02 rs2901297 10 q q26.13 ATE1 123521484 3.23E− 1.08 0.125 0.117 A (SEQ ID NO: 0874) 05 gagggaatggccatta[A/G] gtaaatgctctttaga 02 rs1470996 10 q q26.13 FAM53B 126331555 2.39E− 1.11 0.184 0.169 A (SEQ ID NO: 0875) 05 caggtcccacgatacc[A/G] tcaggaatgtccgttt 02 rs7919338 10 q q26.2 ADAM12 127731365 6.00E− 1.10 0.276 0.258 A (SEQ ID NO: 0876) 02 agttaagaaaagtgtc[A/G] caggctaaggaactgg 03 rs7076942 10 q q26.3 GLRX3| 132374743 2.51E− 1.13 0.292 0.266 C (SEQ ID NO: 0877) TCERG1L 04 attgtagacttgcacg[A/C] ggggctgtatgggctc 03 rs4880419 10 q q26.3 INPP5A 134456109 7.78E− 0.92 0.411 0.432 A (SEQ ID NO: 0878) 03 ggggacccctgctccc[A/G] gagtgacaggggagga 03 rs2814183 10 q q26.3 JAKMIP3 133948347 4.01E− 0.89 0.462 0.489 G (SEQ ID NO: 0879) 04 cgcaaccgcgtgaggc[A/G] acagaaccgacgggca 03 rs12774814 10 # #N/A PITRM1   3182572 1.26E− 0.89 0.241 0.264 A (SEQ ID NO: 0880) N/A 03 tttattacccacagtc[A/C] ccctcggtctgaaaat 03 rs11038044 11 p p11.2 ALX4|  44541295 5.37E− 0.86 0.179 0.203 G (SEQ ID NO: 0881) CD82 05 tcaattttcgtccagc[A/G] ttctctgctacactgc 01 exm2264447 11 p p11.2 C11orf49  46963196 1.45E− 20.9 0.004 0.000 A (SEQ ID NO: 0882) 20 2 cacgcctggccaacct[A/C] ttcaccctcaatctaa 03 rs6416127 11 p p11.2 PRDM11  45239959 1.31E− 1.15 0.169 0.151 C (SEQ ID NO: 0883) 03 tcagcatcactaataa[A/C] agaaacacagcgtagt 03 rs4756204 11 p p13 SLC1A2  35292312 4.58E− 1.10 0.418 0.396 A (SEQ ID NO: 0884) 03 gaaaatgagatagaga[A/G] aggaaagaaataatat 03 rs11030997 11 p p14.1 KCNA4|  30206532 2.43E− 0.90 0.337 0.360 G (SEQ ID NO: 0885) FSHB 03 ccctattgggctatta[A/G] tagattggcatttaaa 03 rs4074516 11 p p14.1 LGR4  27465591 5.78E− 1.10 0.441 0.418 G (SEQ ID NO: 0886) 05 attgaaaaaagcctgt[A/G] ggggtgctttgtgcag 02 rs16916435 11 p p14.2 FIBIN|  27030676 1.54E− 1.09 0.095 0.088 G (SEQ ID NO: 0887) BBOX1 05 ctgttgattctaccct[A/G] tgaacagctgggctta 03 rs1602916 11 p p14.3 LUZP2|  25696461 4.84E− 1.09 0.447 0.425 A (SEQ ID NO: 0888) ANO3 03 tcaagaccctgaattc[A/C] atttttttgaatatat 02 rs324204 11 p p14.3 NELL1|  22001998 9.32E− 1.17 0.265 0.235 A (SEQ ID NO: 0889) ANO5 06 tccagtttttatggaa[A/G] ctaccatttactctgt 02 rs324172 11 p p14.3 NELL1|  21952288 3.51E− 1.15 0.326 0.296 A (SEQ ID NO: 0890) ANO5 05 agactcatatcaaaac[A/G] caataagtgtgtggca 02 rs2009912 11 p p14.3 NELL1|  21945004 5.97E− 1.14 0.330 0.301 G (SEQ ID NO: 0891) ANO5 05 tgcttctagttagctt[A/G] tctatagcttccctgt 02 rs10833683 11 p p14.3 NELL1|  21984498 2.53E− 0.87 0.429 0.462 A (SEQ ID NO: 0892) ANO5 05 accctacatacacata[A/G] ctaaatttttttttct 03 rs793283 11 p p15.1 E2F8|  19264497 1.07E− 0.88 0.205 0.226 A (SEQ ID NO: 0893) NAV2 03 tgtggctcgcagattt[A/G] aaataaagcagaggtc 03 rs7924734 11 p p15.2 ARNTL  13350747 8.93E− 1.10 0.270 0.252 G (SEQ ID NO: 0894) 03 gagagtcacaggaagg[A/G] cccctttacgtcggat 03 rs12290622 11 p p15.2 ARNTL  13314307 4.97E− 1.10 0.310 0.290 G (SEQ ID NO: 0895) 03 agtagatagtggtcca[A/G] gcctagtatttttaac 03 rs7949336 11 p p15.2 ARNTL  13319894 1.22E− 1.09 0.273 0.255 G (SEQ ID NO: 0896) 02 tcccccagaggtgtgt[A/G] tggctagttagctcac 03 rs10766066 11 p p15.2 RASSF10|  13278027 2.73E− 1.08 0.296 0.280 G (SEQ ID NO: 0897) ARNTL 02 attagtgtgcagttac[A/G] tagcttgggcccagac 03 rs11042937 11 p p15.3 MRVI1|  10745394 3.79E− 1.12 0.520 0.492 A (SEQ ID NO: 0898) CTR9 04 cagcacatgaatatgg[A/C] ggcctgctgtgtgcca 03 rs10834648 11 p p15.4 LOC650368|  3645345 2.92E− 1.11 0.325 0.303 G (SEQ ID NO: 0899) TRPC2 03 ctagcctatacttaac[A/G] cataagtttcatccat 03 rs17403795 11 p p15.4 LYVE1  10581217 2.51E− 0.86 0.106 0.122 A (SEQ ID NO: 0900) 03 aaaagattgggctgaa[A/G] ggaaagagatgagatg 03 rs4910630 11 p p15.4 0R52M1|   4590639 2.59E− 0.89 0.393 0.421 A (SEQ ID NO: 0901) C11orf40 04 ccctcctgctgccctc[A/G] gtttagggtttacaag 03 rs12271195 11 p p15.4 SYT9   7463443 2.27E− 0.86 0.116 0.132 A (SEQ ID NO: 0902) 03 ctcagtgaaaatggct[A/G] aggggaggagcttttc 02 rs1908177 11 p p15.4 TRIM68|   4659419 6.34E− 0.87 0.389 0.424 A (SEQ ID NO: 0903) OR51D1 06 tctcctctttcacccc[A/C] acatgcaattcaactt 03 rs1865558 11 p p15.4 WEE1|   9650585 1.83E− 1.11 0.289 0.267 A (SEQ ID NO: 0904) SWAP70 03 tatatctccatgatat[A/G] taatccaagatatata 02 rs885414 11 p p15.4 ZNF195|   3644307 1.01E− 1.16 0.189 0.168 C (SEQ ID NO: 0905) ART5 02 cttatttgtgagagaa[C/G] agaaacctccagggtg 02 exm926722 11 q q13.1 SCYL1  65305309 3.44E− 9.50 0.010 0.001 A (SEQ ID NO: 0906) 14 cggtgctccagtcgtc[A/C] tgctgggccagcacag 03 rs10752564 11 q q13.3 FGF19|  69540990 1.84E− 1.13 0.322 0.295 A (SEQ ID NO: 0907) FGF4 04 ggaggaagcggctgtc[A/G] cagtggctgggcttag 02 exm936578 11 q q13.3 PPFIA1  70170536 1.14E− 5.27 0.007 0.000 G (SEQ ID NO: 0908) 16 cttactaaagaactca[A/G] tgtatgcagggaacag 03 rs11228498 11 q q13.3 TPCN2|  68870298 9.14E− 1.11 0.508 0.482 A (SEQ ID NO: 0909) MYEOV 05 ttgcatttgttttggg[A/G] actgtctgaggttaga 02 rs10751211 11 q q13.4 ARAP1  72405223 3.03E− 1.18 0.202 0.177 A (SEQ ID NO: 0910) 05 tggcagcagtggagat[A/G] gacagagcagagagat 02 exm937263 11 q q13.4 DHCR7  71155161 1.41E− 35.8 0.004 0.000 A (SEQ ID NO: 0911) 08 6 tgaccagtacagctgc[A/G] ccctgactggccctgt 02 rs6592850 11 q q14.1 ODZ4  79226201 9.43E− 1.19 0.407 0.366 G (SEQ ID NO: 0912) 05 aataagcaataataaa[A/G] atgtgacttttacagc 03 rs10831309 11 q q21 ENDOD1|  94881894 5.60E− 0.91 0.449 0.471 A (SEQ ID NO: 0913) SESN3 03 tcatataacttagcta[A/G] gtcattgtgaaatttt 03 rs16922232 11 q q21 LOC  95304581 8.66E− 1.26 0.033 0.026 A (SEQ ID NO: 0914) 100129203| 03 catggagaacaggtgt[A/G] FAM76B acctaagtgcagagcc 03 rs2123325 11 q q22.1 CNTN5  99959543 4.27E− 0.88 0.279 0.305 G (SEQ ID NO: 0915) 04 tctaccaaacatacaa[A/G] aaagagctgatatcaa 03 rs7128754 11 q q22.1 JRKL|  97618161 1.23E− 1.09 0.366 0.348 A (SEQ ID NO: 0916) CNTN5 02 aaatcctggtgaacac[A/C] tgtgccttttcacaga 03 rs11212569 11 q q22.1 JRKL|  97623375 7.12E− 1.12 0.351 0.326 C (SEQ ID NO: 0917) CNTN5 04 atggtgcttttttcaa[A/C] catacccatgaccaat 03 rs12792912 11 q q22.2 LOC 102801303 1.97E− 0.93 0.414 0.432 C (SEQ ID NO: 0918) 100288111| 02 ctcacatttaaactga[A/C] MMP13 ggaatcataaagtaac 03 rs12788925 11 q q22.2 LOC 102801847 1.80E− 0.93 0.413 0.431 G (SEQ ID NO: 0919) 100288111| 02 aaaagaaattctgggt[A/G] MMP13 tctccagagagggaat 02 rs1784408 11 q q22.2 MMP20 102469509 2.13E− 1.11 0.367 0.343 G (SEQ ID NO: 0920) 02 aaaagaagacctttaa[C/G] gctcaacaacatgcat 02 exm952255 11 q q22.3 CASP12 104768141 5.64E− 6.54 0.020 0.005 A (SEQ ID NO: 0921) 12 aatgccatctagaaag[A/G] tcttgatcagcaactt 03 rs10891431 11 q q23.2 LOC 112641531 1.95E− 0.92 0.240 0.256 A (SEQ ID NO: 0922) 100132686| 02 ccagccaatgggagag[A/G] NCAM1 tgaatgctagagggtt 03 rs2073848 11 q q23.2 ZBTB16 114051904 7.66E− 1.15 0.178 0.159 G (SEQ ID NO: 0923) 04 agagctcccttcatgc[A/G] attaaagtatgactga 03 rs3782007 11 q q23.2 ZBTB16 114066438 4.47E− 1.15 0.207 0.186 A (SEQ ID NO: 0924) 04 gataatctcaatatag[A/G] cctcgcatggagtaag 03 rs11215574 11 q q23.3 CADM1 115363443 3.37E− 0.93 0.245 0.260 G (SEQ ID NO: 0925) 02 gttttcaccatgggag[A/G] aagaaaacacaaataa 02 exm960718 11 q q23.3 PHLDB1 118516274 5.43E− 33.1 0.007 0.000 A (SEQ ID NO: 0926) 15 7 ggaggagggtgagcac[A/G] cctatgatacgctgag 01 rs11217801 11 q q23.3 POU2F3 120165942 2.66E− 1.25 0.132 0.109 G (SEQ ID NO: 0927) 06 ctaacagatagcgccc[A/G] ggttggaggcaaagca 03 rs17671708 11 q q24.1 LOC 123306172 1.59E− 1.11 0.147 0.134 G (SEQ ID NO: 0928) 100128242 02 cctcttcatattttca[A/G] ctttgtgcagtgaaaa 03 rs10892895 11 q q24.1 UBASH3B 122630672 2.34E− 1.14 0.086 0.076 G (SEQ ID NO: 0929) 02 gtgttcactcctttgt[A/G] taattccctcccctca 03 rs1946091 11 q q24.2 KIRREL3 126612903 3.20E− 1.10 0.388 0.366 G (SEQ ID NO: 0930) 03 tatctgagatgaggcc[A/G] tcagtgaggacctcct 02 exm968612 11 q q24.2 RPUSD4 126081523 1.59E− Inf 0.003 0.000 A (SEQ ID NO: 0931) 08 cgacgcgctccacctg[A/G] gcgccgccatcttaca 03 rs11221660 11 q q24.3 RICS| 129182778 1.35E− 0.92 0.388 0.407 A (SEQ ID NO: 0932) BARX2 02 ctgaggtttccgggat[A/G] aggagagggtgtggcg 03 rs7122696 11 q q25 NTM 132001390 1.81E− 1.16 0.215 0.192 A (SEQ ID NO: 0933) 04 acaaggctgcactttc[A/G] tagggttccatcataa 03 rs7310913 12 p p11.23 ITPR2  26854487 1.45E− 1.09 0.315 0.297 C (SEQ ID NO: 0934) 02 ccagaccctatacata[A/C] gaataaaatgttacat 03 rs11048661 12 p p11.23 ITPR2  26854124 1.31E− 1.11 0.355 0.331 C (SEQ ID NO: 0935) 03 ggcagtgaaagtcatg[A/C] ttgtaccgcaatcaat 02 rs11054439 12 p p13.2 ETV6  11895308 7.91E− 0.88 0.336 0.366 A (SEQ ID NO: 0936) 05 atagggactcagaaaa[A/G] gcatcattcccttcat 02 rs2051525 12 p p13.2 ETV6  11888423 7.12E− 0.88 0.345 0.375 A (SEQ ID NO: 0937) 05 ccctaataaacaaact[A/G] cttaattgaacagccc 03 rs17181375 12 p p13.31 ANO2   5678868 6.25E− 1.15 0.109 0.097 A (SEQ ID NO: 0938) 03 gtctcaatcccagcca[A/G] gagtgaataatagatg 03 rs7296720 12 p p13.32 TSPAN9   3374920 2.50E− 1.19 0.128 0.110 G (SEQ ID NO: 0939) 04 tagaaatttgtcgaac[A/G] tgtttgataaaatgga 03 rs2429166 12 p p13.33 CACNA2D4   2025907 1.12E− 0.88 0.181 0.201 G (SEQ ID NO: 0940) 03 gtctcctggattgggc[A/G] tgaggagggctttggg 03 rs10774066 12 p p13.33 FKBP4|   2920736 3.61E− 1.18 0.144 0.125 G (SEQ ID NO: 0941) ITFG2 04 aaaaaaaaatgattct[A/G] ccttatctgggatttt 03 rs10848706 12 p p13.33 FKBP4|   2919701 3.45E− 1.18 0.144 0.125 G (SEQ ID NO: 0942) ITFG2 04 tgcagatatattctga[A/G] gctgaactgtgttaca 03 rs2286601 12 p p13.33 ITFG2   2932177 2.25E− 1.18 0.148 0.128 A (SEQ ID NO: 0943) 04 cacttccctttctgac[A/G] tatcccctgatgtaag 03 rs3759411 12 p p13.33 LOC   2901570 1.10E− 1.19 0.145 0.124 G (SEQ ID NO: 0944) 100288472| 04 catccaccttatctgt[A/G] LOC728147 ggtgactcctgctggg 03 rs3814249 12 p p13.33 NRIP2   2936276 1.57E− 1.14 0.174 0.156 G (SEQ ID NO: 0945) 03 tggaagggcagacacc[A/G] tagtccccagctacct 03 rs3814250 12 p p13.33 NRIP2   2936049 1.89E− 1.18 0.147 0.127 A (SEQ ID NO: 0946) 04 ctgcttgggctgggtc[A/G] aaggctctgctgactg 03 rs11062376 12 p p13.33 NRIP2|   2950208 3.76E− 1.17 0.146 0.127 A (SEQ ID NO: 0947) FOXM1 04 ttatgtccccaaaccc[A/G] cctggggcaagggggt 02 exm997545 12 q q13.11 HDAC7  48187329 6.43E− 12.7 0.013 0.001 A (SEQ ID NO: 0948) 21 1 tccccggtgctgcccc[A/G] ggggagccgcccagcc 03 rs7488270 12 q q13.12 SPATS2  49784365 1.05E− 1.24 0.087 0.071 A (SEQ ID NO: 0949) 04 ttcatccttatttggc[A/G] ttaaagttaacacaaa 03 rs7309610 12 q q13.12 SPATS2  49783814 1.61E− 1.24 0.087 0.071 A (SEQ ID NO: 0950) 04 atttcaacttgaacaa[A/G] aaaacaaaggcgttag 03 rs186231 12 q q13.13 FIGNL2  52212489 9.30E− 1.16 0.145 0.127 A (SEQ ID NO: 0951) 04 tgcacaggaggctgag[A/G] tgggagagagaaaaag 03 rs172559 12 q q13.13 FLJ33996  52204246 7.90E− 1.16 0.143 0.125 A (SEQ ID NO: 0952) 04 taatatttggcaaagc[A/G] ttgccacttacccact 03 rs3900362 12 q q13.13 SCN8A  52108030 2.18E− 1.19 0.135 0.116 G (SEQ ID NO: 0953) 04 ctgttatagtttccac[A/G] tcacaactaactgttt 03 rs303808 12 q q13.13 SCN8A  52163789 2.88E− 1.16 0.169 0.149 G (SEQ ID NO: 0954) 04 aaaggggatgaggagc[A/G] gatgggctggggacac 03 rs303771 12 q q13.13 SCN8A  52152192 8.38E− 1.17 0.131 0.114 G (SEQ ID NO: 0955) 04 gttcgacattttgcaa[A/G] tctctttaatgtctgg 03 rs2580807 12 q q13.13 SCN8A  52174231 6.32E− 1.17 0.143 0.125 A (SEQ ID NO: 0956) 04 cctttccttccaggtc[A/G] tttgagtcaagttgaa 03 rs715930 12 q q13.3 B4GALNT1  58023981 1.85E− 0.88 0.190 0.210 A (SEQ ID NO: 0957) 03 ggctgctgtaagtgac[A/C] agttgtagttgcctgt 03 rs11173855 12 q q14.1 LOC  61637441 1.33E− 0.90 0.438 0.463 A (SEQ ID NO: 0958) 100289417| 03 tagactaaaattaata[A/C] FAM19A2 agataagagttgaaac 03 rs10784186 12 q q14.1 LOC  61604963 2.08E− 0.91 0.425 0.449 A (SEQ ID NO: 0959) 100289417| 03 attatcatttcttctt[A/C] FAM19A2 atttattcctagtctg 02 rs2270482 12 q q14.1 PPM1H  63087901 2.89E− 0.82 0.131 0.155 A (SEQ ID NO: 0960) 05 tccctataaaggaaga[A/G] gtagtcagtgtggtga 03 rs2711666 12 q q14.1 SLC16A7  60132210 1.06E− 0.92 0.437 0.457 A (SEQ ID NO: 0961) 02 tgggctgctatttctc[A/G] tggaccaataacaaga 03 rs10431559 12 q q14.1 SLC16A7|  60244639 7.38E− 0.94 0.438 0.452 A (SEQ ID NO: 0962) LOC 02 attagtcttgggtcca[A/G] 100289417 attaatttcatgatca 03 rs10437957 12 q q14.1 SLC16A7|  60202218 3.19E− 0.93 0.440 0.457 A (SEQ ID NO: 0963) LOC 02 ctaataatctccctag[A/G] 100289417 ttttgtcctttgtcta 03 rs7307997 12 q q14.2 AVPR1A|  63557914 8.89E− 0.92 0.414 0.434 G (SEQ ID NO: 0964) DPY19L2 03 gaattcttgactgcct[A/G] tgtgttactcttcttc 03 rs6581482 12 q q14.2 AVPR1A|  63682898 1.85E− 0.92 0.324 0.342 A (SEQ ID NO: 0965) DPY19L2 02 gtaaagattgggaaaa[A/G] cttgcactaacttcca 03 rs11612942 12 q q14.2 AVPR1A|  63704363 1.38E− 1.16 0.142 0.125 A (SEQ ID NO: 0966) DPY19L2 03 ctggatgttggggaga[A/G] ttaacttgagttcaga 02 exm1020169 12 q q15 CAND1  67706476 4.89E− 40.9 0.004 0.000 A (SEQ ID NO: 0967) 10 6 ctcttctctgcttctg[A/G] aatggttagcagtgct 02 rs1861933 12 q q15 LOC  68842405 2.18E− 1.16 0.214 0.190 G (SEQ ID NO: 0968) 100286998| 05 aagtaaaggaattata[A/G] LOC actagctgctgcttca 100288856 02 rs7298169 12 q q15 LOC  68854225 1.61E− 1.21 0.129 0.109 G (SEQ ID NO: 0969) 100286998| 05 gccaaagctgtcagaa[A/G] LOC acatcctacaatgcac 100288856 02 rs2216437 12 q q15 LOC  68850924 4.99E− 1.19 0.097 0.082 G (SEQ ID NO: 0970) 100286998| 05 accccttgttgagcac[A/G] LOC tggatacctttgaggt 100288856 02 rs3863373 12 q q15 PTPRR  71288396 3.63E− 1.09 0.349 0.330 A (SEQ ID NO: 0971) 05 tatttttagtaaaata[A/C] taaatacacaccttgt 03 rs2035151 12 q q21.2 E2F7  77445086 8.84E− 1.11 0.098 0.089 G (SEQ ID NO: 0972) 05 tgtctcctcaacccac[A/G] tttgaaaggggctcca 03 rs12422952 12 q q21.2 GLIPR1  75881018 3.38E− 0.89 0.372 0.400 A (SEQ ID NO: 0973) 04 ctggagttgcttttgg[A/G] gtctgcattttaacaa 03 rs7969930 12 q q21.2 GLIPR1L2|  75867565 6.61E− 0.90 0.375 0.401 G (SEQ ID NO: 0974) GLIPR1 04 ttttgacagatagttg[A/G] caacagacatgtacag 03 rs11180540 12 q q21.2 GLIPR1L2|  75873161 5.42E− 0.89 0.375 0.402 A (SEQ ID NO: 0975) GLIPR1 04 gctacaggtgtgcctg[A/G] aatgtttctttacttt 03 rs10785190 12 q q21.2 GLIPR1L2|  75819844 7.57E− 0.90 0.375 0.401 G (SEQ ID NO: 0976) GLIPR1 04 aatacaactagagaga[A/G] atatatagatacttaa 03 rs733880 12 q q21.2 KRR1|  75976164 7.43E− 1.11 0.495 0.470 G (SEQ ID NO: 0977) LOC 05 taaaattgaccatttt[A/G] 100289143 cagacataatggcaag 03 rs6582294 12 q q21.2 KRR1|  76034992 7.29E− 0.90 0.383 0.409 A (SEQ ID NO: 0978) LOC 04 gaatgaatcatcccca[A/G] 100289143 tttgtttcttgctaca 03 rs12423804 12 q q21.31 PPP1R12A|  80580111 7.63E− 0.90 0.436 0.462 A (SEQ ID NO: 0979) C12orf64 04 acctgatgggagagac[A/G] cggctaagtaggaaag 03 rs4882448 12 q q21.31 TMTC2|  83746599 1.24E− 0.92 0.467 0.486 G (SEQ ID NO: 0980) SLC6A15 02 tcctctgacatggatg[A/G] ttgtggcattagtaac 03 rs17790382 12 q q22 EEA1  93230276 4.98E− 0.85 0.087 0.100 C (SEQ ID NO: 0981) 03 atgcttcatagcttac[A/C] aagttatttcagagat 03 rs11829776 12 q q22 FGD6  95531442 2.93E− 0.89 0.195 0.214 G (SEQ ID NO: 0982) 03 ataggactgaacaaca[A/G] agaattgctgatatct 03 rs12579299 12 q q22 NR2C1  95442242 1.10E− 0.88 0.193 0.214 G (SEQ ID NO: 0983) 03 cgcaataactgctatt[A/G] taactgacttaacagg 02 rs14121 12 q q22 VEZT  95694394 9.10E− 0.85 0.262 0.294 G (SEQ ID NO: 0984) 06 gaacagacttttggtg[A/G] tgaggaggaagaacaa 01 rs3596 12 q q22 VEZT  95696420 8.71E− 1.16 0.508 0.471 G (SEQ ID NO: 0985) 08 gaagtcagtggttctc[A/G] gttgtattagtggggt 02 rs10859856 12 q q22 VEZT  95631276 5.23E− 1.15 0.505 0.470 G (SEQ ID NO: 0986) 07 cctctggtttggtgat[A/G] tcagtggaggctgata 02 rs7959730 12 q q23.1 NEDD1|  97495927 3.16E− 1.09 0.347 0.328 G (SEQ ID NO: 0987) RMST 05 aatgcaaatgaaaaca[A/G] tatgagaagccactac 03 rs10861688 12 q q23.3 CRY1 107394048 9.61E− 0.85 0.169 0.193 A (SEQ ID NO: 0988) 05 tgtgctgcacaaggac[A/G] actgaaacaaaagaat 03 rs973724 12 q q23.3 CRY1| 107578877 4.68E− 0.89 0.316 0.342 G (SEQ ID NO: 0989) BTBD11 04 taacaagaatgaccca[A/G] tctatatgatcaactt 03 rs1896058 12 q q23.3 LOC 108405763 7.17E− 1.11 0.436 0.410 A (SEQ ID NO: 0990) 100287556| 04 catgaaagtgtcacta[A/G] WSCD2 aaaactctacctactg 03 rs11068393 12 q q24.22 FBXO21 117623136 3.08E− 0.87 0.193 0.217 G (SEQ ID NO: 0991) 04 ggagagagaaatatct[A/G] tcagtggaacaactgt 03 rs1466852 12 q q24.22 FBXO21 117591843 1.57E− 0.86 0.192 0.216 A (SEQ ID NO: 0992) 04 atagacactggcccac[A/G] gtgttgttgaaaagaa 01 rs10431397 12 q q24.23 KSR2 118106194 1.38E− 2.43 0.021 0.009 A (SEQ ID NO: 0993) 15 cctatgatctggtgga[A/G] caccctccctcctgaa 03 rs10846578 12 q q24.31 DNAH10 124400278 7.08E− 1.12 0.306 0.282 A (SEQ ID NO: 0994) 04 tgtctgttcatacacc[A/G] gaatatcattcagccc 03 rs7975815 12 q q24.31 DNAH10 124388129 3.30E− 0.72 0.019 0.026 G (SEQ ID NO: 0995) 03 gtgagagtaggtcact[A/G] ttgaggcccccataca 02 exm1044289 12 q q24.31 P2RX7 121622550 1.22E− 6.57 0.009 0.001 A (SEQ ID NO: 0996) 10 tgccgctggaggatcc[A/G] gaaagagtttccgaag 03 rs4765052 12 q q24.32 TMEM132B 126043965 1.91E− 0.87 0.140 0.158 A (SEQ ID NO: 0997) 03 atcacaaagccatact[A/G] caggtacagggtctga 03 rs4765044 12 q q24.32 TMEM132B 125981136 9.73E− 0.90 0.375 0.400 A (SEQ ID NO: 0998) 04 ctcctgggttgccccc[A/G] tccttgagccaatgta 02 exm1054045 12 q q24.33 POLE 133263886 1.21E− 7.12 0.007 0.001 C (SEQ ID NO: 0999) 08 catgtctctgaggagc[C/G] gcgggcggcggcgcgc 02 rs2012359 13 q q12.12 PARP4  25078073 2.11E− 1.16 0.135 0.119 G (SEQ ID NO: 1000) 02 cacatattgcaagcta[C/G] gatattattcaatttt 03 rs3117849 13 q q12.13 ATP8A2  26299179 4.22E− 1.34 0.025 0.018 A (SEQ ID NO: 1001) 03 tgtcctcccagagtct[A/G] tcatctatcaggaagt 03 rs7328428 13 q q12.3 HMGB1|  31083678 8.44E− 1.24 0.062 0.051 A (SEQ ID NO: 1002) USPL1 04 aattaagaatattggg[A/G] cacggccaggcgtggt 03 rs1543660 13 q q12.3 KIAA0774  29855650 6.01E− 1.29 0.031 0.024 G (SEQ ID NO: 1003) 03 ttaagtcactgcataa[A/G] tatctgtcacacaaat 03 rs9506012 13 q q12.3 LOC  29135021 2.97E− 1.16 0.183 0.161 G (SEQ ID NO: 1004) 100287487| 04 ccaaagctccctccac[A/G] POMP gcagccaacacaccct 03 rs663528 13 q q12.3 UBL3|  30607076 4.92E− 0.90 0.464 0.492 A (SEQ ID NO: 1005) KATNAL1 04 tctgaacaaagatgac[A/C] ggaggagctgccttgg 03 rs8002871 13 q q12.3 UBL3|  30574667 4.74E− 1.12 0.464 0.437 G (SEQ ID NO: 1006) KATNAL1 04 tgtgctttggagtttg[A/G] gcggcagaaccgcgta 02 rs9595159 13 q q13.1 FRY  32798953 4.76E− 1.16 0.230 0.204 A (SEQ ID NO: 1007) 05 tatttcccccgaataa[A/G] agccttatataatgtt 02 rs394307 13 q q13.1 LOC122038|  33569834 3.37E− 1.08 0.442 0.422 G (SEQ ID NO: 1008) KL 05 actgagtagtcatcag[A/G] atatttggttgtgttg 03 rs1199994 13 q q13.3 CSNK1A1L|  37694027 1.50E− 1.23 0.063 0.052 G (SEQ ID NO: 1009) POSTN 03 caagtactcaataaat[A/G] taaacaaacctgtcat 03 rs9315468 13 q q13.3 FAM48A|  37667508 8.35E− 0.90 0.416 0.442 A (SEQ ID NO: 1010) CSNK1A1L 04 atgaaatagtaaatac[A/C] agccttacactttgaa 03 rs9603439 13 q q13.3 FREM2  39402920 9.64E− 1.20 0.055 0.046 A (SEQ ID NO: 1011) 03 gagctgggtttatatg[A/C] attgacatgaaaagtt 03 rs9603442 13 q q13.3 FREM2  39406629 5.34E− 1.21 0.055 0.046 A (SEQ ID NO: 1012) 03 aactggttatttccta[A/G] agctgagattgtgagg 03 rs2766484 13 q q14.13 SIAH3|  46443060 1.56E− 1.13 0.409 0.380 C (SEQ ID NO: 1013) ZC3H13 04 attacaagtcagcagt[A/C] caagaaaggaacaggg 03 rs9567586 13 q q14.13 SIAH3|  46431655 3.94E− 1.12 0.409 0.382 G (SEQ ID NO: 1014) ZC3H13 04 acaaagaatataaaca[A/G] agtacacagaagaagt 02 exm1068520 13 q q14.2 CYSLTR2  49281785 5.84E− 5.52 0.017 0.003 T (SEQ ID NO: 1015) 17 agtctgtctttgcata[A/T] acccactttccatgtc 03 rs2765760 13 q q14.2 FAM10A4|  50851577 1.59E− 0.83 0.123 0.145 A (SEQ ID NO: 1016) DLEU7 04 ggcacagtcacacgcc[A/C] acgaggccagccctgc 03 rs9591076 13 q q14.2 HTR2A|  48127371 1.44E− 1.60 0.017 0.011 A (SEQ ID NO: 1017) SUCLA2 04 ccttcagtttctccct[A/G] gggcttcattatggct 03 rs9596839 13 q q14.3 OLFM4|  54264395 3.64E− 0.93 0.283 0.298 A (SEQ ID NO: 1018) LOC 02 taattttaattgatcc[A/G] 100287887 tcacctctactgtttg 03 rs9563182 13 q q14.3 OLFM4|  54395310 1.71E− 0.90 0.155 0.169 G (SEQ ID NO: 1019) LOC gtaattattaaattac[A/G] 100287887 02 tggaagttccttgccc 03 rs9316660 13 q q14.3 OLFM4|  54353562 2.90E− 0.88 0.146 0.163 G (SEQ ID NO: 1020) LOC 03 tttacttacctcttac[A/G] 100287887 tagtcctaagcacaat 03 rs9563183 13 q q14.3 OLFM4|  54396931 1.71E− 0.90 0.155 0.169 C (SEQ ID NO: 1021) LOC 02 gaggagagctagtgaa[A/C] 100287887 taaaagcctaagtata 03 rs12860689 13 q q14.3 OLFM4|  54315805 2.89E− 0.88 0.146 0.163 G (SEQ ID NO: 1022) LOC 03 tttggggatatagcct[A/G] 100287887 gaaatgtgtactttta 03 rs9568924 13 q q14.3 OLFM4|  54360952 3.94E− 0.88 0.148 0.165 C (SEQ ID NO: 1023) LOC 03 ctgtattacacattat[A/C] 100287887 cataatctagaaatga 03 rs9568902 13 q q14.3 OLFM4|  54324954 3.15E− 0.88 0.145 0.162 A (SEQ ID NO: 1024) LOC 03 aaagctgtttgttttt[A/G] 100287887 agaagttctatgctca 03 rs2806731 13 q q14.3 OLFM4|  54290333 3.33E− 0.89 0.191 0.210 G (SEQ ID NO: 1025) LOC 03 aacttctgtttttact[A/G] 100287887 ttttctaggcaatgtc 03 rs9568919 13 q q14.3 OLFM4|  54352229 2.71E− 0.88 0.146 0.163 C (SEQ ID NO: 1026) L0C 03 tggtgtctagaactgc[A/C] 100287887 tctagcaagtgggagg 02 rs2786266 13 q q21.32 LOC730236|  68327766 2.37E− 1.30 0.078 0.061 G (SEQ ID NO: 1027) KLHL1 03 tgctggacaagtgtaa[A/G] gaatctggggtttaga 03 rs287548 13 q q22.1 KLF5|  73905783 1.15E− 0.76 0.033 0.043 A (SEQ ID NO: 1028) LOC647281 03 gagggtttggctttag[A/G] ctttgttagggcaagt 03 rs9543642 13 q q22.1 LOC  75008312 2.48E− 1.13 0.405 0.377 A (SEQ ID NO: 1029) 100288208| 04 tagaagcacacctagc[A/G] LOC647288 tatttaaaacttggag 03 rs9543662 13 q q22.1 LOC  75066010 1.30E− 0.89 0.434 0.464 G (SEQ ID NO: 1030) 100288208| 04 acggatgaatcaaaac[A/G] LOC647288 ttaagctctctaaaag 03 rs1337278 13 q q31.1 SLITRK1|  86316853 1.97E− 1.08 0.406 0.388 G (SEQ ID NO: 1031) SLITRK6 02 aaataatccttgatac[A/G] gtactgaatattttgt 03 rs4344612 13 q q31.1 SPRY2|  81574866 3.11E− 1.14 0.273 0.248 C (SEQ ID NO: 1032) SLITRK1 04 ttatctcaaaaaaaat[A/C] tgtaggtataaatttg 03 rs7336590 13 q q31.1 SPRY2|  81529694 3.80E− 0.89 0.448 0.476 A (SEQ ID NO: 1033) SLITRK1 04 aatccatttgaaattg[A/G] cagtgtttttatattt 03 rs12865263 13 q q31.1 SPRY2|  81362430 8.35E− 1.15 0.174 0.154 A (SEQ ID NO: 1034) SLITRK1 04 cttcagtcttcgtaca[A/G] aaacacttactttata 03 rs4536348 13 q q31.1 SPRY2|  81562924 5.42E− 1.13 0.165 0.149 G (SEQ ID NO: 1035) SLITRK1 03 cctggtaatttgatca[A/G] tcattaagctatcctt 03 rs2348445 13 q q31.2 LOC  89846656 1.08E− 1.15 0.156 0.138 G (SEQ ID NO: 1036) 100287432| 03 tgaagaatttactcac[A/G] LOC144776 tggggaaataaaggcc 03 rs11616543 13 q q31.2 LOC  89298757 3.61E− 1.13 0.180 0.163 A (SEQ ID NO: 1037) 100287432| 03 tgtattctctagtcag[A/G] LOC144776 ttctctttccagcttg 03 rs11620369 13 q q31.3 GPC5|  93873495 1.12E− 0.82 0.068 0.082 A (SEQ ID NO: 1038) GPC6 03 tagtattttaggtaac[A/G] atgagtaaatcttaag 03 rs9556267 13 q q31.3 GPC5|  93839833 6.97E− 0.81 0.067 0.082 G (SEQ ID NO: 1039) GPC6 04 acagagtctggaaata[A/G] gaccgatgaaaccagg 03 rs7322277 13 q q31.3 GPC6  94826895 7.99E− 0.87 0.174 0.195 G (SEQ ID NO: 1040) 04 agcacaaacttttgct[A/G] aatagcatgtcatcta 03 rs7329232 13 q q31.3 GPC6  94828678 1.97E− 0.86 0.113 0.130 G (SEQ ID NO: 1041) 03 atatcggttctgctat[A/G] tctatgagttcctttc 03 rs9301082 13 q q33.2 DAOA| 106586930 1.40E− 1.12 0.302 0.279 A (SEQ ID NO: 1042) LOC728192 03 aatagatgaggaagtt[A/G] aagtccaaaaatagtc 03 rs9519858 13 q q33.2 DAOA| 106583444 1.03E− 1.12 0.304 0.280 A (SEQ ID NO: 1043) LOC728192 03 aaagtgaatgagaaca[A/G] tactgataataatagc 02 rs9583036 13 q q33.2 DAOA| 106389385 8.28E− 1.29 0.104 0.083 G (SEQ ID NO: 1044) LOC728192 04 tgcctgtgacacaata[T/G] tgaaatcttacttaaa 02 rs277836 13 q q33.3 MYO16 109710600 2.10E− 1.15 0.394 0.362 G (SEQ ID NO: 1045) 05 atgttgaaagggtgcc[A/G] gtgccttggtgatcaa 03 rs12018760 13 # #N/A OLFM4|  54308253 3.67E− 0.88 0.145 0.162 A (SEQ ID NO: 1046) N/A LOC 03 ttgattcttaatctgg[A/G] 100287887 ggtgtttatttcccta 02 exm1085390 14 q q11.2 EDDM3A  21216136 2.92E− 9.13 0.008 0.001 A (SEQ ID NO: 1047) 12 tggcgtagatggatat[A/G] ttgataacatagaaga 02 rs227865 14 q q11.2 OR4E2|  22953607 4.78E− 1.27 0.076 0.061 G (SEQ ID NO: 1048) DAD1 05 tcgtcaatgttttaaa[A/G] ggtaggagttgttaca 03 rs2233859 14 q q11.2 RNASE3  21359808 9.05E− 0.90 0.398 0.423 A (SEQ ID NO: 1049) 04 ataaccgagaccggat[A/C] ggggagtagttacttc 03 rs2300850 14 q q12 AKAP6  33271488 9.28E− 1.18 0.131 0.113 G (SEQ ID NO: 1050) 05 agttcataatcttcca[A/G] gcctccatagtctggt 02 exm- 14 q q12 NOVA1|  27406892 6.53E− 4.47 0.011 0.002 A (SEQ ID NO: 1051) rs17111920 LINC00645 10 tagactaatgcaagca[A/C] aaaatttccatttgct 03 rs8009605 14 q q12 PRKD1  30254780 1.23E− 0.86 0.208 0.233 G (SEQ ID NO: 1052) 04 ggaagtcttattcgga[A/G] caatcagtcaagaaaa 02 rs17489969 14 q q12 STXBP6|  26642640 7.02E− 1.36 0.073 0.055 C (SEQ ID NO: 1053) NOVA1 04 catgcaccgaaatctc/T/C] tcatgatggagaattt 02 rs17110902 14 q q12 STXBP6|  26673425 9.11E− 1.12 0.169 0.153 A (SEQ ID NO: 1054) NOVA1 07 ggactgcaaggtaatc[A/G] tcaagggactcttaga 02 rs1012146 14 q q12 STXBP6|  26678953 6.04E− 1.12 0.169 0.153 A (SEQ ID NO: 1055) NOVA1 07 ttcatttaattttaca[A/C] ggaagagtttaaaaaa 03 rs2899875 14 q q21.1 CLEC14A|  39001144 8.58E− 0.91 0.475 0.499 G (SEQ ID NO: 1056) LOC283547 05 tatcattgctatttcc[A/G] tgtttggtcaaggcat 03 rs8005701 14 q q21.2 LOC644589|  46883709 7.79E− 0.92 0.419 0.439 A (SEQ ID NO: 1057) LOC 03 aaattataacaaaaga[A/G] 100289583 aattttactcttataa 03 rs10138214 14 q q21.2 LOC644589|  46866809 1.36E− 0.92 0.418 0.437 A (SEQ ID NO: 1058) LOC 02 agtgccagcattctga[A/G] 100289583 ccataatttttgtgac 03 rs1669786 14 q q21.2 LOC644589|  46894155 8.60E− 0.92 0.420 0.440 G (SEQ ID NO: 1059) LOC 03 gggttcaacagtctat[A/G] 100289583 tttttagcagactgtc 03 rs2415982 14 q q21.2 LOC644589|  46865899 9.90E− 0.92 0.417 0.437 A (SEQ ID NO: 1060) LOC 03 aggcctgcctgtgtat[A/G] 100289583 actgtaaatattcatt 03 rs12883384 14 q q21.3 MDGA2  47403684 6.84E− 1.11 0.434 0.407 A (SEQ ID NO: 1061) 04 tcttggcttgaactgc[A/C] aatcttaaaagttaat 03 rs11846126 14 q q21.3 RPL10L|  47249450 2.32E− 0.89 0.455 0.484 G (SEQ ID NO: 1062) MDGA2 04 tgaaatattgtaaatc[A/G] gtggttttgagtgtct 03 rs1253706 14 q q22.1 GNG2  52400377 2.84E− 1.12 0.456 0.427 A (SEQ ID NO: 1063) 04 aaagaaaatgagagcc[A/G] ctgctcgagtgaaggg 03 rs4271525 14 q q22.1 GNG2  52408987 5.65E− 1.12 0.428 0.401 A (SEQ ID NO: 1064) 05 ttttcatgatggcttt[A/G] tggctatttttttagg 03 rs10498440 14 q q22.1 GNG2  52413573 8.43E− 1.11 0.429 0.403 G (SEQ ID NO: 1065) 04 aaagtactaggccagc[A/G] ttccaaagaagtgttt 03 rs1618825 14 q q22.1 GNG2  52407340 1.32E− 1.11 0.439 0.414 A (SEQ ID NO: 1066) 03 tgattgggaaagagtg[A/G] ctgagtgtgcaaggtg 03 rs7157151 14 q q22.1 NID2|  52571583 7.51E− 1.12 0.311 0.287 A (SEQ ID NO: 1067) PTGDR 04 acgttactcatcaaat[A/G] tatacaatgtagctaa 03 rs941630 14 q q22.1 NID2  52557650 7.32E− 1.10 0.236 0.218 A (SEQ ID NO: 1068) PTGD|R 03 ttgtctatcagttgcc[A/G] tcttccattggccaag 03 rs34096981 14 q q22.3 C14orf34|  56302744 6.76E− 1.12 0.315 0.291 A (SEQ ID NO: 1069) LOC 05 ggcagagttacacctc[A/G] 100286940 taaacaaactattcaa 03 rs2342595 14 q q22.3 C14orf34|  56271486 8.48E− 1.12 0.312 0.288 A (SEQ ID NO: 1070) LOC 05 agggccaagctgccaa[A/G] 100286940 aacttcttgaggtctg 02 rs1953358 14 q q22.3 C14orf34|  56295580 5.14E− 0.88 0.458 0.489 A (SEQ ID NO: 1071) LOC 05 ggcagcatcaaagtca[A/G] 100286940 atgactgacccaaggc 02 rs12896938 14 q q22.3 TBPL2|  55955102 3.40E− 1.12 0.236 0.216 G (SEQ ID NO: 1072) C14orf33 05 ctatgctctggtttct[A/G] tatttctagaacttgt 03 rs12880763 14 q q22.3 TBPL2|  55970308 9.86E− 1.12 0.225 0.206 G (SEQ ID NO: 1073) C14orf33 05 taatctttaaattgtt[A/G] catatttagcaagtgt 03 rs12884010 14 q q22.3 TBPL2|  55944612 1.96E− 1.13 0.372 0.344 G (SEQ ID NO: 1074) C14orf33 04 gctgtgctcccagcca[A/G] cagccagaatcaactg 02 rs7156144 14 q q24.1 TMEM229B  67979713 5.74E− 0.92 0.415 0.435 A (SEQ ID NO: 1075) 02 taaatctgatacaacc[A/G] aaataaacacagtata 03 rs17104036 14 q q24.3 C14orf179|  76573554 1.38E− 1.18 0.060 0.051 A (SEQ ID NO: 1076) C14orf118 02 cactctagaagaccct[A/G] caaatcagaaccagag 02 exm1114136 14 q q24.3 COQ6  74427993 6.12E− Inf 0.004 0.000 G (SEQ ID NO: 1077) 12 gcccccaagcgtagcc[A/G] gggtggatgccaaaag 02 exm1113959 14 q q24.3 ZNF410  74388791 4.89E− 40.9 0.004 0.000 G (SEQ ID NO: 1078) 10 6 aagcctcttcaagcaa[A/G] ctactgcccattagtg 03 rs7148059 14 q q32.11 KCNK13|  90657405 8.80E− 1.12 0.174 0.159 A (SEQ ID NO: 1079) PSMC1 05 gttgtcaatgctaaac[A/G] agaaagggtccctgga 03 rs1241719 14 q q32.12 CPSF2|  92673710 3.01E− 1.09 0.226 0.212 A (SEQ ID NO: 1080) SLC24A4 02 tcaaaccagccctgcc[A/G] gtgcccttgtgtccct 02 rs1257415 14 q q32.2 BCL11B  99698931 3.94E− 1.14 0.525 0.493 C (SEQ ID NO: 1081) 05 cactccagggccccca[A/C] gtggattcccccatcg 02 rs2614459 14 q q32.2 BCL11B  99691180 2.49E− 1.15 0.314 0.285 C (SEQ ID NO: 1082) 06 cattgtgggaagctct[A/C] gagatggggccatcct 03 rs2793321 14 q q32.2 BCL11B  99676623 1.04E− 1.14 0.326 0.298 A (SEQ ID NO: 1083) 04 ctgcagtgcttattct[A/G] tctcttttgtttgttt 03 rs756055 14 q q32.2 DEGS2|YY1 100691178 6.05E− 0.88 0.376 0.408 G (SEQ ID NO: 1084) 05 atcaggggaaaagcat[A/G] aactcaaaatagatga 03 rs7153665 14 q q32.2 YY1 100730920 8.62E− 0.88 0.376 0.408 A (SEQ ID NO: 1085) 05 aagggcgatgaatcct[A/G] ggccaggctgtgcaga 02 exm1134843 14 q q32.33 PACS2 105858969 1.20E− Inf 0.003 0.000 A (SEQ ID NO: 1086) 07 cagccagggtgtcggc[A/G] ccgagctgatggggct 02 rs8179187 15 q q11.2 UBE3A  25652326 2.69E− 1.28 0.081 0.065 C (SEQ ID NO: 1087) 05 gagggtcgcactttca[A/C] aaatgagtcagctggt 03 rs12437614 15 q q12 GABRG3  27706661 2.08E− 1.28 0.060 0.047 A (SEQ ID NO: 1088) 04 cagcaagagttattgc[A/G] aagagaaacaacaaag 03 rs939981 15 q q13.1 LOC727808|  30290306 3.19E− 1.15 0.124 0.110 A (SEQ ID NO: 1089) LOC 03 ggtcctttctaaaaat[A/G] 100128435 gtcaccccaatccatc 03 rs12905328 15 q q13.1 LOC727808|  30239328 1.72E− 0.88 0.202 0.222 A (SEQ ID NO: 1090) LOC 03 attaatattttatgtt[A/G] 10012|8435 catgatttagatttat 02 rs12438794 15 q q14 MEIS2  38146571 8.47E− 1.08 0.076 0.071 A (SEQ ID NO: 1091) TMCO5A 07 tcatggaactaaaagt[A/G] agcatctcaagagact 02 rs8041665 15 q q14 MEIS2|  38150179 2.56E− 1.08 0.077 0.072 A (SEQ ID NO: 1092) TMCO5A 07 agcgtatattatcttc[A/G] aagagcatttttattt 02 rs8037309 15 q q14 MEIS2|  38150438 2.77E− 1.08 0.077 0.072 A (SEQ ID NO: 1093) TMCO5A 07 gagcatccacatccat[A/G] aggctgctgaattcat 03 rs12907066 15 q q14 RYR3  33990976 7.93E− 1.12 0.319 0.295 A (SEQ ID NO: 1094) 04 tctccagaagatccct[A/G] agcacatgtctggatg 03 rs7165303 15 q q14 RYR3  33693677 2.31E− 0.89 0.391 0.420 G (SEQ ID NO: 1095) 04 ttcagcactattcagc[A/G] cctatcactgccagct 03 rs2279663 15 q q14 RYR3  33952326 5.80E− 1.13 0.157 0.142 A (SEQ ID NO: 1096) 03 cccagacattttaacc[A/G] atatggccagtataaa 01 exm1159600 15 q q21.1 DUT  48623812 4.41E− 1.65 0.010 0.000 A (SEQ ID NO: 1097) 08 cgcacggcagagggcc[A/G] aagccgcggtactctc 03 rs17645290 15 q q21.2 USP8  50787955 1.92E− 1.10 0.191 0.177 G (SEQ ID NO: 1098) 02 tacaaacacttgccag[A/G] tttagaaacacctgta 02 rs16940167 15 q q21.3 AQP9|  58683697 7.99E− 1.18 0.176 0.154 G (SEQ ID NO: 1099) LIPC 05 ttatgggcccagaatg[A/G] ttccagatcagaattt 03 rs1280415 15 q q21.3 CGNL1  57749193 4.60E− 1.12 0.082 0.074 G (SEQ ID NO: 1100) 02 tattgaacattctaca[A/G] atttttataaaaaagg 03 rs1280416 15 q q21.3 CGNL1  57749300 2.10E− 1.24 0.055 0.045 A (SEQ ID NO: 1101) 03 ttctttgtcagctacc[A/G] ttgctataaaaccttt 03 rs2017176 15 q q21.3 KIAA1370|  53006147 6.68E− 0.89 0.440 0.469 A (SEQ ID NO: 1102) ONECUT1 05 tgactaattacactgg[A/G] gagtccatcaacatct 02 rs17543144 15 q q21.3 KIAA1370|  53008923 2.07E− 0.88 0.438 0.468 A (SEQ ID NO: 1103) ONECUT1 05 tggttggaacatagcc[A/G] tgacagctagccaaca 03 rs2414407 15 q q21.3 RAB27A  55556228 4.27E− 1.14 0.131 0.117 A (SEQ ID NO: 1104) 03 caaacaaacagaaaaa[A/G] taaccctggctatagt 03 rs1991574 15 q q21.3 UNC13C  54484950 6.41E− 0.87 0.200 0.223 A (SEQ ID NO: 1105) 04 gaaggcccagtgggaa[A/G] ccgagtagtgctacag 03 rs12440360 15 q q21.3 UNC13C  54491059 1.01E− 0.90 0.450 0.476 C (SEQ ID NO: 1106) 03 atccaaatcaagaaaa[A/C] aatctctgaattgcca 03 rs16950635 15 q q22.33 SMAD3  67418205 7.50E− 1.27 0.052 0.041 A (SEQ ID NO: 1107) 04 ggggtaatttattgcc[A/G] ccgctcgcttcaccag 03 rs16951541 15 q q23 LOC  68276895 2.17E− 1.23 0.090 0.074 A (SEQ ID NO: 1108) 100286942| 04 attctgcagacacaca[A/G] PIAS1 tcctttttgcctacaa 02 exm1173822 15 q q23 THSD4  72023502 9.46E− 17.8 0.006 0.000 A (SEQ ID NO: 1109) 11 7 cgtgcactacgagtac[A/G] tgatcatggggaccaa 03 rs1130741 15 q q24.1 MPI  75189930 1.47E− 1.13 0.477 0.448 A (SEQ ID NO: 1110) 04 tggtacaggggacagt[A/G] atagccagcacaccca 03 rs2415251 15 q q24.2 COX5A|  75242155 2.06E− 1.12 0.502 0.473 A (SEQ ID NO: 1111) RPP25 04 atctgagcccttgggt[A/G] cccctgcctttggaga 03 rs11855944 15 q q24.3 LINGO1|  78088127 8.41E− 1.11 0.195 0.179 C (SEQ ID NO: 1112) LOC645752 03 tgccacttgctgccag[A/C] cctggctgaagcaggg 03 rs4075024 15 q q24.3 LINGO1|  78093898 1.18E− 1.10 0.198 0.183 G (SEQ ID NO: 1113) LOC645752 02 ttgtttttctgattac[A/G] acagaagacccaacaa 03 rs15939 15 q q24.3 RCN2  77241542 2.36E− 0.89 0.105 0.117 G (SEQ ID NO: 1114) 02 gctcatcatgatagaa[A/G] tagtcatcatggagct 02 exml181151 15 q q25.1 ADAMTS7  79089098 2.26E− Inf 0.003 0.000 A (SEQ ID NO: 1115) 09 gagtctcgacgggagc[A/G] ttgggagcagcggcag 02 exm1182536 15 q q25.1 IL16  81572094 1.94E− 34.6 0.004 0.000 A (SEQ ID NO: 1116) 08 4 caattacagaatcatg[A/G] tggaggtttctctgca 03 rs12905510 15 q q25.3 AGBL1|  87944954 1.60E− 1.13 0.353 0.325 G (SEQ ID NO: 1117) NCRNA00052 04 tgataagctggacttc[A/G] taaaaactatacacat 03 rs2016517 15 q q25.3 AKAP13  86229618 1.28E− 1.12 0.275 0.253 A (SEQ ID NO: 1118) 03 catggtaaaatacttt[A/G] gctatatttccatcag 03 rs11630274 15 q q25.3 AKAP13  86288387 9.24E− 1.12 0.288 0.265 A (SEQ ID NO: 1119) 04 tgaccagacgcctggt[A/G] cagactgggccttctt 03 rs1978391 15 q q25.3 KLHL25  86311695 9.49E− 1.12 0.288 0.264 A (SEQ ID NO: 1120) 04 ggatgctggttcctcc[A/G] aaaacaaagagcttca 03 rs3743332 15 q q25.3 LOC  86303751 1.33E− 1.09 0.288 0.270 G (SEQ ID NO: 1121) 100288896 02 accagaaaggtgacca[A/G] gacagattttttaagg 03 rs11634975 15 q q25.3 PDE8A  85606478 3.07E− 1.11 0.309 0.288 G (SEQ ID NO: 1122) 03 aacagtgacctattct[A/G] gtaaacacattacgaa 03 rs11629962 15 q q25.3 PDE8A  85530028 1.18E− 1.12 0.268 0.246 A (SEQ ID NO: 1123) 03 agcaagatctcgtctc[A/G] acaaaaaaaaagttta 03 rs6496766 15 q q25.3 PDE8A|  85702375 1.06E− 1.11 0.400 0.375 C (SEQ ID NO: 1124) LOC728121 03 atgaaccaactatatg[A/C] tgtctacaagaaacac 03 rs12905479 15 q q26.1 LOC390638|  91711209 1.44E− 0.93 0.431 0.450 A (SEQ ID NO: 1125) SV2B 02 cggcctttgtggtgct[A/G] tttggtttcatcccca 02 exm1190729 15 q q26.1 UNC45A  91486258 1.72E− Inf 0.003 0.000 A (SEQ ID NO: 1126) 08 tccttgagagacttcc[A/G] gggcaccgctttaatc 03 rs896070 15 q q26.2 LOC145820|  96428860 1.06E− 1.17 0.198 0.175 A (SEQ ID NO: 1127) NR2F2 04 aaggctctgaggtttt[A/G] gtaccccagaaagatt 03 rs1025833 15 q q26.2 SPATA8|  98224547 2.07E− 1.25 0.073 0.059 A (SEQ ID NO: 1128) LOC91948 04 tattaccatgaacttt[A/G] gtaaaagttacaaata 02 rs8024630 15 q q26.2 SPATA8|  98034118 4.66E− 1.14 0.526 0.494 A (SEQ ID NO: 1129) LOC91948 05 ttagaaaatctataac[A/G] gtaaaaagtacattag 03 rs12910816 15 q q26.2 SPATA8|  98249133 2.76E− 1.26 0.065 0.052 C (SEQ ID NO: 1130) LOC91948 04 aaaacctctcacatga[A/C] taagcttacaaaatag 03 rs8041786 15 q q26.2 SPATA8|  97896453 8.59E− 1.18 0.112 0.096 G (SEQ ID NO: 1131) LOC91948 04 ttctatagcagacatt[A/G] gtctctgaacttgggt 02 exm1193980 15 q q26.3 LRRK1 101567912 8.37E− Inf 0.005 0.000 A (SEQ ID NO: 1132) 13 ccgcagccgggacgac[A/G] acgtgcagtacctgac 02 rs7173796 15 q q26.3 PCSK6| 102148666 1.66E− 1.22 0.134 0.113 A (SEQ ID NO: 1133) TM2D3 05 ggcaggcagggaacag[A/G] tgattagtaaccaaag 01 exm1194576 15 q q26.3 TM2D3 102192537 1.63E− 46.4 0.013 0.000 C (SEQ ID NO: 1134) 21 1 ggtgctcccgctgagg/C]G] gcctccgcgccttgtg 03 rs1132812 16 p p11.2 CORO1A  30198151 2.94E− 0.89 0.438 0.466 A (SEQ ID NO: 1135) 04 aggtgtgggagatccc[A/G] gatgggggcctgatgc 03 rs11859842 16 p p11.2 SLC7A5P1|  29661217 1.65E− 1.13 0.497 0.467 A (SEQ ID NO: 1136) SPN 04 cagcaaagtctgacca[A/G] tctaaagtaaccactc 02 rs12447415 16 p p11.2 SPN|QPRT  29682945 5.03E− 1.11 0.412 0.386 A (SEQ ID NO: 1137) 06 agggacccttctaaaa[A/G] gtcactgtgggctggg 02 rs2343605 16 p p12.1 TNRC6A|  24848663 1.33E− 0.91 0.369 0.392 G (SEQ ID NO: 1138) SLC5A11 05 gagaccagcctacgca[A/G] catagaacctgtctct 03 rs7200734 16 p p12.3 XYLT1  17443547 1.00E− 1.08 0.495 0.475 A (SEQ ID NO: 1139) 02 agtaatacttcccata[A/C] gagatagttgtgaaat 02 exm1219737 16 p p13.11 KIAA0430  15729650 1.26E− Inf 0.003 0.000 A (SEQ ID NO: 1140) 07 ttctgatttcacaagc[A/G] gggctccagggcattt 03 rs1541702 16 p p13.13 C16orf75  11445552 2.32E− 1.11 0.140 0.128 G (SEQ ID NO: 1141) 02 tctacaaccatgtcag[A/G] acacaatctaactcct 03 rs434762 16 p p13.13 GSPT1  12009781 4.81E− 1.24 0.069 0.056 G (SEQ ID NO: 1142) 04 cagaggcggcggcggc[A/G] gcagctcaaccctcct 03 rs7204004 16 p p13.2 C16orf72   9332745 2.64E− 0.86 0.168 0.190 A (SEQ ID NO: 1143) GRIN2A| 04 ctcccctgacccaggt[A/G] aggcagtgagtacccc 02 rs12443943 16 p p13.2 GRIN2A|  10428747 2.59E− 1.15 0.236 0.212 G (SEQ ID NO: 1144) LOC 05 atgtcctctggagcac[A/G] 100287628 ccccacagcaagttgg 02 exm1215795 16 p p13.3 ALG1   5122041 2.22E− 16.4 0.008 0.001 A (SEQ ID NO: 1145) 15 5 cacggcttctcggtga[A/C] cctcctggggttctgc 02 exm1207746 16 p p13.3 C16orf59   2512728 1.48E− Inf 0.005 0.000 A (SEQ ID NO: 1146) 14 aggctgcaggagctgc[A/G] tgcaggtgagaccccg 02 rs2171226 16 p p13.3 LOC650177|   5588451 1.22E− 0.88 0.427 0.458 A (SEQ ID NO: 1147) A2BP1 06 atcctcctcatttttc[A/G] tctaaaagccttagtc 03 rs2294619 16 p p13.3 MAPK8IP3   1814440 1.89E− 1.13 0.200 0.181 G (SEQ ID NO: 1148) 03 gcccaagagcgcccac[A/G] cgtctcccgagaagaa 03 rs3211995 16 p p13.3 SLC9A3R2   2089006 4.89E− 1.15 0.187 0.166 A (SEQ ID NO: 1149) 04 gcatgcgcgctctcag[A/G] ataaacaggccctgcc 02 exm1211849 16 p p13.3 SLX4   3640815 8.05E− 43.9 0.005 0.000 C (SEQ ID NO: 1150) 11 3 aggggcacggggagca[C/G] aggcccctgagcagga 03 rs13334798 16 q q12.1 ABCC11  48244717 5.74E− 1.18 0.080 0.069 G (SEQ ID NO: 1151) 05 aaaattcaaatttttc[A/G] tggagggcaaacacag 03 rs7194667 16 q q12.1 ABCC11  48242898 5.35E− 1.18 0.080 0.068 C (SEQ ID NO: 1152) 05 cccatcccctcagctt[A/C] tattctgagctcaatg 03 rs3910446 16 q q12.1 LOC388276|  52196841 1.68E− 1.11 0.369 0.345 A (SEQ ID NO: 1153) TOX3 03 gagtcacagtgatggc[A/G] acccggtattctcagc 03 rs8052698 16 q q12.2 TOX3|CHD9  52967995 3.62E− 1.12 0.474 0.446 A (SEQ ID NO: 1154) 04 tgcgccatcatgccct[A/G] cgcatttcatttaaat 03 rs4784181 16 q q21 CDH8|CDH11  62346479 8.70E− 0.92 0.410 0.431 A (SEQ ID NO: 1155) 03 atgagcatgtgatcca[A/G] tgatagtcaatgaaat 03 rs11861466 16 q q21 GOT2|  59495475 7.02E− 1.09 0.434 0.413 A (SEQ ID NO: 1156) LOC644649 03 gtcaaaaaaagcatca[A/G] taaataagtagagagt 03 rs1582600 16 q q21 GOT2|  59314789 1.09E− 1.09 0.397 0.378 C (SEQ ID NO: 1157) LOC644649 02 taaatgtagtcatggc[A/C] gaaagctgagtgggtg 03 rs1364204 16 q q21 GOT2|  59411217 1.77E− 1.08 0.385 0.367 A (SEQ ID NO: 1158) LOC644649 02 tgatcaggttttgggc[A/G] agggtctgcttttttg 02 rs7193968 16 q q22.1 IL34  70672952 4.90E− 0.88 0.443 0.474 C (SEQ ID NO: 1159) 03 tgccagctttacaagc[C/G] acagaatcaccaaaac 02 rs4149499 16 q q22.2 CHST4  71570413 5.95E− 1.36 0.057 0.042 A (SEQ ID NO: 1160) 06 caacaatggcaccagt[A/C] cttctccaaatcattt 03 rs150617 16 q q22.2 DHX38  72139396 1.82E− 1.20 0.124 0.106 A (SEQ ID NO: 1161) 04 gagcaggacatacagg[A/G] agggaaaaatgagtcc 03 rs4788591 16 q q22.2 PKD1L3  72020323 1.51E− 1.09 0.233 0.218 A (SEQ ID NO: 1162) 02 tgtgatgtgatacttg[A/G] tagtactgaaggaaac 03 rs152828 16 q q22.2 TXNL4B  72123886 1.93E− 1.20 0.123 0.105 A (SEQ ID NO: 1163) 04 tctaccctcagtcata[A/G] gcaggaggaaatacca 02 exm1257256 16 q q22.2 ZFHX3  72821344 2.06E− 5.63 0.015 0.003 A (SEQ ID NO: 1164) 15 gacttcctggaggcgt[A/G] gggggaagcggaggag 03 rs12102460 16 q q23.1 WWOX  79093317 6.10E− 1.30 0.028 0.022 G (SEQ ID NO: 1165) 03 tgagatgtagagcttg[A/G] cacctgcatataaagt 02 rs9923563 16 q q23.1 WWOX  78615460 3.64E− 1.16 0.262 0.234 G (SEQ ID NO: 1166) 05 ttcctagaggttcaca[A/G] taaatctaaaaagatc 02 rs12598440 16 q q23.1 WWOX  78576107 1.74E− 1.14 0.508 0.474 G (SEQ ID NO: 1167) 05 tccggcagtgtttacg[A/G] agggctggagatacac 02 rs11150085 16 q q23.1 WWOX  78567094 1.50E− 1.22 0.117 0.098 A (SEQ ID NO: 1168) 05 caggtcagccagttgg[A/G] aacagagttgacggag 03 rs2943768 16 q q23.1 WWOX  78612914 1.77E− 1.13 0.206 0.187 C (SEQ ID NO: 1169) 03 ttacattatacatctt[A/C] ggcatttttttccttt 01 rs4319778 16 q q23.1 WWOX  78552954 1.99E− 1.16 0.423 0.387 A (SEQ ID NO: 1170) 06 tttctaatttaatctt[A/G] tacatgagacagctat 02 rs2978632 16 q q23.1 WWOX  78559880 7.70E− 1.14 0.341 0.312 A (SEQ ID NO: 1171) 05 gcagataggatgatac[A/G] tgtgctctgcaaccat 03 rs16947885 16 q q23.1 WWOX  78551317 3.56E− 1.24 0.077 0.064 G (SEQ ID NO: 1172) 04 caccagaactgaaatt[A/G] tttccagctatgttta 03 rs30405 16 q q23.2 LOC729251|  79621818 9.13E− 0.87 0.181 0.202 G (SEQ ID NO: 1173) MAF 04 gaacacagaaactgca[A/G] tggcttttggacgcta 01 rs30428 16 q q23.2 LOC729251|  79598399 2.68E− 0.86 0.349 0.384 G (SEQ ID NO: 1174) MAF 06 cttcttccatcaggga[A/G] gttatcaggctcaaag 03 rs3784925 16 q q23.2 LOC729251|  79605583 2.50E− 1.16 0.189 0.167 A (SEQ ID NO: 1175) MAF 04 atcctctgctctccta[A/G] gttcaggcaggataga 03 rs173645 16 q q23.2 LOC729251|  79594409 5.42E− 0.88 0.243 0.267 G (SEQ ID NO: 1176) MAF 04 caaaccattgcatcat[A/G] ttttggactgatagtt 03 rs7206458 16 q q23.3 CDH13  83446995 3.30E− 1.13 0.284 0.259 A (SEQ ID NO: 1177) 04 ttccccaattattatc[A/C] gtcactcctcctccat 02 rs1013465 16 q q23.3 CDH13  83412113 2.31E− 1.14 0.406 0.375 A (SEQ ID NO: 1178) 05 tggccaatccaactga[A/C] ggggacccctttattg 02 exm1263172 16 q q23.3 OSGIN1  83999431 1.18E− Inf 0.003 0.000 G (SEQ ID NO: 1179) 07 gcagtggatcctgacc[A/G] gccgctgagcgccaag 03 rs13521 16 q q24.1 COTL1  84599970 5.86E− 0.88 0.263 0.287 A (SEQ ID NO: 1180) 04 gccaggagctgtgccc[A/G] gtgcctgcagccttca 03 rs11641616 16 q q24.1 FOXL1|  86638543 6.76E− 1.24 0.070 0.057 A (SEQ ID NO: 1181) LOC 04 ttaatcaaatatcggg[A/G] 100288525 ttaaagaatgtatcaa 03 rs7202350 16 q q24.1 FOXL1|  86642680 1.37E− 1.22 0.070 0.058 G (SEQ ID NO: 1182) LOC 03 gcagccccagcaggaa[A/G] 100288525 gacacgataatcgatt 03 rs11642168 16 q q24.1 LOC732275|  86520474 4.54E− 1.13 0.152 0.136 A (SEQ ID NO: 1183) FOXF1 03 aaggggaaacggagcc[A/G] gccaaggacaggtgaa 03 rs7186320 16 q q24.1 TMEM148|  85577092 9.13E− 0.79 0.052 0.065 A (SEQ ID NO: 1184) KIAA0182 05 acatggggaatggggt[A/G] tggactctatggggtg 03 rs2274892 17 p p11.2 TNFRSF13B  16852027 1.23E− 1.13 0.400 0.370 C (SEQ ID NO: 1185) 04 cccaaggcaaacctgc[A/C] tggtgtcacgcagggt 03 rs17793572 17 p p11.2 TNFRSF13B  16843992 5.67E− 1.02 0.292 0.288 A (SEQ ID NO: 1186) 01 tgctctctggatcctg[A/G] aggaagttgatccact 03 rs4792801 17 p p11.2 TNFRSF13B  16845467 6.12E− 1.11 0.438 0.412 G (SEQ ID NO: 1187) 05 caggtcctcaaaaaac[A/G] aaacagagctattatg 03 rs8072293 17 p p11.2 TNFRSF13B  16855878 1.02E− 1.12 0.278 0.255 G (SEQ ID NO: 1188) 03 cacagggcctgtggac[A/G] ggggtggctatgagat 02 rs7223652 17 p p11.2 TNFRSF13B  16864559 3.60E− 1.22 0.325 0.283 G (SEQ ID NO: 1189) 05 gttcttttggatgttt[G/A] cttaggagtggaatta 03 rs7504096 17 p p11.2 TNFRSF13B|  16877083 2.25E− 1.15 0.216 0.192 A (SEQ ID NO: 1190) MPRIP 04 caggccagagccagga[A/G] tctattgcacagttaa 02 rs4441330 17 p p11.2 ZNF286B  18562720 1.22E− 1.12 0.513 0.485 G (SEQ ID NO: 1191) 05 cattcatcaagaagtc[A/G] gataaagggtttaaac 02 rs11078211 17 p p12 HS3ST3A1|  13836036 7.83E− 1.15 0.297 0.270 A (SEQ ID NO: 1192) CDRT15P 05 ttaactcctttcaaac[A/G] atttcctttgtatctt 03 rs10852926 17 p p12 PIRT|  10778976 2.25E− 1.04 0.494 0.484 A (SEQ ID NO: 1193) FLJ45455 01 aaatagagacacagcc[A/G] gagtgctggctatgac 02 rs179521 17 p p12 PMP22|  15173221 9.82E− 1.13 0.387 0.357 A (SEQ ID NO: 1194) TEKT3 05 catctctgagttcctg[A/C] accacttatcaagtgt 02 rs8068414 17 p p12 TEKT3|  15248449 9.77E− 1.15 0.289 0.262 A (SEQ ID NO: 1195) LOC 05 gggagtgtggacacgg[A/G] 100287829 gctgcactgccaggct 02 rs11078672 17 p p13.1 EIF5A   7215142 5.26E− 0.87 0.306 0.336 A (SEQ ID NO: 1196) 05 ctctctcctacctagg[A/G] tggcggtggtggcagc 03 rs8072788 17 p p13.2 NLRP1|   5594285 8.70E− 1.11 0.200 0.184 A (SEQ ID NO: 1197) WSCD1 03 aaataaaggcctgtgg[A/G] cctcagtttcctgtgt 02 rs17804008 17 p p13.2 PITPNM3   6433659 6.08E− 1.12 0.369 0.344 G (SEQ ID NO: 1198) 06 ctgaccctgactttga[A/G] atttcgtctgtaaaat 03 rs907941 17 p p13.2 PITPNM3   6362387 3.70E− 0.89 0.433 0.461 G (SEQ ID NO: 1199) 04 ggagcagcccctcttc[A/G] tctggcccttccacct 03 rs11078612 17 p p13.2 WSCD1|   6067298 8.12E− 0.87 0.101 0.114 G (SEQ ID NO: 1200) AIPL1 03 tattgctcattttttt[A/G] tagatgaggaaactgc 03 rs9894371 17 p p13.2 WSCD1|   6212579 1.92E− 0.91 0.475 0.499 G (SEQ ID NO: 1201) AIPL1 03 ccttgtcttagttcca[A/G] acgtctccctctgtga 03 rs8078781 17 p p13.3 OR1D|2   3008882 8.67E− 1.16 0.082 0.072 A (SEQ ID NO: 1202) OR1G1 05 aacaccatacagcaat[A/G] agcatgaacaacctac 03 rs9902340 17 q q11.2 CCDC55  28476458 3.06E− 1.07 0.503 0.486 C (SEQ ID NO: 1203) 02 gcaatcttactcctct[A/C] tgataacaaatagatc 03 rs11080118 17 q q11.2 CCDC55  28475379 3.31E− 1.07 0.502 0.486 A (SEQ ID NO: 1204) 02 ctatgtctataagtgg[A/G] aaaggctttgtttatt 03 rs9896012 17 q q11.2 CCDC55  28470091 3.12E− 1.07 0.503 0.486 G (SEQ ID NO: 1205) 02 gaagcagatgtgtatg[A/G] ttttggagaaacagaa 03 rs9897794 17 q q11.2 EFCAB5  28296327 2.57E− 1.07 0.507 0.489 C (SEQ ID NO: 1206) 02 gtgacttctttcatca[A/C] cctctggtaaccagac 03 rs3102555 17 q q11.2 SSH2  28044101 5.26E− 0.92 0.464 0.486 G (SEQ ID NO: 1207) 03 tctctgttttaagggc[A/G] gtggatagggtagggt 03 rs10445384 17 q q11.2 SSH2|  28182685 1.59E− 1.08 0.503 0.484 G (SEQ ID NO: 1208) EFCAB5 02 tccttagttggatcag[A/G] cacagactatgaaatt 03 rs10445400 17 q q11.2 SSH2|  28183059 1.33E− 1.08 0.504 0.485 G (SEQ ID NO: 1209) EFCAB5 02 gatgaggtctgtgcat[A/G] ctcctttccccatcaa 03 rs7219163 17 q q11.2 SSH2|  28210703 1.11E− 0.92 0.466 0.486 A (SEQ ID NO: 1210) EFCAB5 02 ttaattctcttcctgg[A/C] cagcctaacttctcct 03 rs9914342 17 q q12 FLJ43826  37190141 5.71E− 0.88 0.238 0.262 G (SEQ ID NO: 1211) 04 gtaaggactttatcca[A/G] aatcacttatgtgtct 03 rs8070269 17 q q12 MRM1|  35134033 3.98E− 1.14 0.146 0.130 A (SEQ ID NO: 1212) LHX1 03 tgatagccatcaccca[A/G] ggagaatggtgaaaga 02 rs3744474 17 q q21.31 C1QL1|  43100070 2.70E− 1.12 0.219 0.199 G (SEQ ID NO: 1213) DCAKD 05 ggatgtgtaagaccct[A/G] tagttaacataacact 03 rs4793598 17 q q21.32 HOXB9|  46743914 7.15E− 1.11 0.387 0.362 G (SEQ ID NO: 1214) PRAC 05 tgctgaactttgtcct[A/G] gcatataattagttac 02 rs12453356 17 q q22 TMEM100  53808950 4.16E− 1.50 0.027 0.018 C (SEQ ID NO: 1215) 05 tagctaacactactac[A/C] caagctaccagaacag 03 rs10512502 17 q q23.3 DDX5  62495009 2.05E− 1.21 0.071 0.059 A (SEQ ID NO: 1216) 03 taatgactaatcagga[A/G] gcaacgtaaccaaaag 02 exm1345526 17 q q23.3 SCN4A  62028920 7.02E− 9.29 0.033 0.002 C (SEQ ID NO: 1217) 18 gacggccccccatcca[C/G] cctcgagctggaccac 02 exm1345636 17 q q23.3 SCN4A  62049749 1.33E− 5.07 0.013 0.003 A (SEQ ID NO: 1218) 12 gctgagccccttcagc[A/G] tagtcaggcgcggggc 03 rs7218921 17 q q24.1 GNA13|  63068976 3.64E− 0.89 0.461 0.489 A (SEQ ID NO: 1219) RGS9 04 tcatgtcctaaccaac[A/G] gaatcaccctggttcc 03 rs2907373 17 q q24.2 FAM20A  66533655 1.19E− 1.13 0.372 0.343 A (SEQ ID NO: 1220) 04 gccagagtctggggcc[A/G] actgttccactgggcc 02 rs8076465 17 q q24.2 PRKAR1A  66513025 3.83E− 1.13 0.372 0.343 A (SEQ ID NO: 1221) 05 ttttgaagtcaagtgc[A/G] ttcctggagatccggt 02 rs8080306 17 q q24.2 PRKAR1A  66508243 1.62E− 1.16 0.314 0.284 C (SEQ ID NO: 1222) 05 gagagcgaagagcagg[A/C] ggaggaacaaaggcga 03 rs2952275 17 q q24.2 PRKAR1A  66518663 1.33E− 1.13 0.372 0.344 A (SEQ ID NO: 1223) 04 atggcttgtactaatg[A/G] cttttgcccattaata 02 rs2302782 17 q q24.2 WIPI1  66446803 8.10E− 1.14 0.334 0.306 G (SEQ ID NO: 1224) 05 aaacaaaaagatggac[A/G] tctttcaagatcaatg 03 rs2952291 17 q q24.2 WIPI1|  66460984 1.20E− 1.14 0.327 0.299 G (SEQ ID NO: 1225) PRKAR1A 04 ctattatgaaattctg[A/G] gtctaaagacattgca 03 rs16969749 17 q q25.2 SEC14L1  75192907 2.88E− 0.87 0.127 0.143 A (SEQ ID NO: 1226) 03 ctaattctgtcagcct[A/G] cttactagaaaccaaa 03 rs4969170 17 q q25.3 SOCS3|PGS1  76360538 7.40E− 1.09 0.358 0.338 A (SEQ ID NO: 1227) 03 gtttttagagaccaca[A/G] cctgctttcttctaga 02 rs9957245 18 p p11.21 LOC  15102421 1.26E− 1.21 0.188 0.161 A (SEQ ID NO: 1228) 100131500| 03 tcctaaaaggtttcac[G/A] LOC644669 tcaagcataagtttct 03 rs1852893 18 p p11.21 LOC  15082789 1.12E− 1.14 0.282 0.256 G (SEQ ID NO: 1229) 100131500| 04 attatctggagtcagg[A/G] LOC644669 ttcttctttagcagtg 02 rs1893187 18 p p11.22 VAPA|  10295300 2.33E− 1.20 0.170 0.146 A (SEQ ID NO: 1230) APCDD1 06 actcaccttgtcatca[A/G] aagagaaaggaccatg 03 rs206475 18 p p11.22 VAPA|  10295284 4.30E− 0.89 0.444 0.472 A (SEQ ID NO: 1231) APCDD1 04 gggcactaggtgccac[A/G] ctcaccttgtcatcag 03 rs206470 18 p p11.22 VAP|A  10296623 5.55E− 0.89 0.316 0.341 A (SEQ ID NO: 1232) APCDD1 04 cattactcagaattat[A/G] tctggagcaaataaca 02 rs189982 18 p p11.22 VAPA|  10302384 1.52E− 1.20 0.157 0.135 A (SEQ ID NO: 1233) APCDD1 05 cttacaccatgtttct[A/G] tcagtatcaaacaaag 02 rs11080401 18 p p11.22 VAPA|  10304345 2.69E− 1.20 0.177 0.153 A (SEQ ID NO: 1234) APCDD1 06 ggtttggagtctgatc[A/G] cttggattctggcagg 03 rs475001 18 p p11.32 C18orf2|   2192946 8.65E− 1.15 0.102 0.090 A (SEQ ID NO: 1235) METTL4 03 ttcatttgaatgaaac[A/G] ggtcactttaaaaatt 03 rs1507732 18 p p11.32 C18orf2|   1464859 1.29E− 1.14 0.181 0.162 A (SEQ ID NO: 1236) METTL4 03 ctgcaaagttccatta[A/G] aaagatggtggacaaa 03 rs561312 18 p p11.32 C18orf2|   2194248 7.75E− 1.15 0.103 0.091 A (SEQ ID NO: 1237) METTL4 03 cctgtgcctgagatga[A/G] gcaggaatctccaggg 03 rs2419027 18 q q12.1 CDH2|DSC3  27785716 4.67E− 1.09 0.493 0.470 A (SEQ ID NO: 1238) 03 tttacttttggcctcc[A/G] ttgacccagatgggga 03 rs954640 18 q q12.1 CDH2|DSC3  27688654 1.89E− 1.10 0.475 0.451 A (SEQ ID NO: 1239) 03 tttacagatactgact[A/G] cataaaacaacaatcc 03 rs9967020 18 q q12.1 CDH2|DSC3  27681568 5.95E− 1.09 0.492 0.471 A (SEQ ID NO: 1240) 03 caaaaggacgtactgc[A/G] tgatgctaatttataa 03 rs8090231 18 q q12.1 CDH2|DSC3  27755950 3.86E− 1.10 0.468 0.446 A (SEQ ID NO: 1241) 03 acagacttaagtgaag[A/G] cccgcattcctacttt 03 rs12456839 18 q q12.1 CDH2|DSC3  25895735 2.66E− 0.89 0.218 0.238 A (SEQ ID NO: 1242) 03 aagctaggagcatttt[A/G] aatatgtatttctgga 03 rs11564361 18 q q12.1 CDH2|DSC3  25904868 2.12E− 0.89 0.217 0.238 G (SEQ ID NO: 1243) 03 aacactagttgagtaa[A/G] tggatacaattgaggt 03 rs9952363 18 q q12.1 CDH2|DSC3  27690198 6.81E− 1.11 0.479 0.452 A (SEQ ID NO: 1244) 04 ctagacctactgccat[A/G] agttttgtaagacaca 03 rs12967345 18 q q12.1 CDH2|DSC3  27758155 2.29E− 1.12 0.221 0.202 G (SEQ ID NO: 1245) 03 caggacaggcaacaca[A/G] taacttgatacaaaag 03 rs8094149 18 q q12.2 BRUNOL4  34979873 2.11E− 0.89 0.365 0.394 C (SEQ ID NO: 1246) 04 agtgaggctcatctgc[A/C] tgggtgagaagcgaaa 03 rs1511938 18 q q12.2 BRUNOL4|  35967920 8.63E− 0.90 0.461 0.488 G (SEQ ID NO: 1247) LOC647946 04 atgctgtagccacttg[A/G] taacatctttcttgaa 03 rs12604671 18 q q12.2 BRUNOL4|  36039666 4.68E− 1.12 0.343 0.318 A (SEQ ID NO: 1248) LOC647946 04 aacgacttggaaatag[A/G] ctataaatgtagaagg 03 rs2625068 18 q q12.2 LOC647946  37172774 1.34E− 0.88 0.337 0.366 A (SEQ ID NO: 1249) 04 tttaatttaaaataat[A/C] acattctggggtgcca 02 rs10502725 18 q q12.2 LOC647946  37111762 4.65E− 0.88 0.365 0.396 A (SEQ ID NO: 1250) 05 ccaatgacataatatc[A/C] gaccttaaaaaaatga 03 rs2852346 18 q q12.2 LOC647946  37194499 7.92E− 0.90 0.475 0.501 A (SEQ ID NO: 1251) 04 caggtcttatttcttc[A/G] tttacgttatgtgaaa 03 rs2255757 18 q q12.3 LOC  42958392 1.63E− 1.11 0.416 0.392 C (SEQ ID NO: 1252) 100131669| 03 gccatcccctatctct[A/C] SLC14A2 ttgaaaactgacttca 03 rs2726262 18 q q12.3 LOC647946  37200183 1.99E− 0.89 0.351 0.379 A (SEQ ID NO: 1253) 04 cctctcccatgatcca[A/G] tcatctctccccaggc 03 rs2726267 18 q q12.3 LOC647946  37208969 2.06E− 0.88 0.338 0.366 C (SEQ ID NO: 1254) 04 gtattcaaatcttggc[A/C] aatatccaactagcaa 03 rs2726232 18 q q12.3 LOC647946  37212167 3.33E− 0.89 0.465 0.493 G (SEQ ID NO: 1255) 04 gaagaatgaatgtctt[A/G] ggatacaattaagtga 02 rs10163756 18 q q12.3 LOC647946|  38325874 7.90E− 1.18 0.171 0.148 C (SEQ ID NO: 1256) KC6 05 aaaccattacataggt[A/C] tcaaaatccaaatatt 03 rs981500 18 q q12.3 LOC647946|  38024748 5.32E− 1.17 0.151 0.133 C (SEQ ID NO: 1257) KC6 04 aaacattttccagagt[A/C] aagaaagagtagaaaa 03 rs16973432 18 q q12.3 LOC647946|  38041069 5.69E− 1.16 0.151 0.133 C (SEQ ID NO: 1258) KC6 04 gtcattttatgagtga[A/C] aaaaagaaacaaatgg 03 rs4799515 18 q q12.3 LOC647946|  37387509 9.04E− 0.90 0.429 0.455 A (SEQ ID NO: 1259) KC6 04 aagcaatcctagctgg[A/G] gtagagctggcatttt 03 rs12455503 18 q q12.3 LOC647946|  37373687 4.31E− 0.89 0.340 0.367 G (SEQ ID NO: 1260) KC6 04 aacacaatggggttga[A/G] catcacctcatattca 03 rs10502850 18 q q12.3 SETBP1  42589714 1.87E− 1.28 0.060 0.048 A (SEQ ID NO: 1261) 04 acctgttctgtttgat[A/G] tgcagactgaggctca 02 exm1386239 18 q q21.1 C18ORF32  47008746 1.26E− Inf 0.003 0.000 A (SEQ ID NO: 1262) 07 atcacagatttctgtt[A/G] gtccttttgttggtaa 03 rs16949181 18 q q21.1 LOC647055  45945536 1.16E− 0.90 0.444 0.470 G (SEQ ID NO: 1263) 03 ttccaggtcccctttc[A/G] cttcctgtgctgttgc 03 rs1377016 18 q q21.1 LOXHD1  44063598 1.14E− 0.92 0.314 0.333 A (SEQ ID NO: 1264) 02 ggtcttgacatgccag[A/G] caagttctctcttggg 03 rs10502876 18 q q21.1 LOXHD1|  44257422 4.14E− 0.73 0.032 0.043 A (SEQ ID NO: 1265) ST8SIA5 04 agggaaagtgcttaac[A/G] tagcttgataaatgct 03 rs17681615 18 q q21.2 DCC  50124619 2.09E− 0.90 0.316 0.339 A (SEQ ID NO: 1266) 03 cattatactaaatacc[A/G] aggttaagagaataaa 03 rs9964201 18 q q21.2 DCC  50600552 1.82E− 1.14 0.092 0.082 A (SEQ ID NO: 1267) 02 agttactatgatttaa[A/C] tgtttcattgtgttta 03 rs12327270 18 q q21.2 TCF4  53168073 5.79E− 1.11 0.065 0.058 G (SEQ ID NO: 1268) 05 gcttcattatatcaca[A/G] agaatgagctcaaata 03 rs1506647 18 q q21.31 TCF4|  54136314 1.01E− 1.28 0.047 0.037 A (SEQ ID NO: 1269) TXNL1 03 ctacctttaagaaaca[A/G] gataaaaaataatgat 02 rs1469488 18 q q21.32 CCBE1  57228450 6.44E− 1.26 0.085 0.069 A (SEQ ID NO: 1270) 05 gcttttgggtacacag[A/G] cccattacatacatga 02 rs2332079 18 q q21.32 LOC728111|  58594189 4.68E− 0.90 0.416 0.443 G (SEQ ID NO: 1271) CDH20 05 ccaatttcctttaaaa[A/G] agaggcttctgaaatt 02 rs17609410 18 q q21.32 LOC728111|  58563363 1.11E− 0.90 0.386 0.412 A (SEQ ID NO: 1272) CDH20 05 atagcacctctttctg[A/C] agctctcgggactctt 02 rs1979787 18 q q21.32 LOC728111|  58684971 2.68E− 0.88 0.407 0.438 G (SEQ ID NO: 1273) CDH20 05 tcctaactgtctaact[A/G] tatgaattccaaaagt 02 rs2332197 18 q q21.32 LOC728111|  58717342 1.65E− 0.88 0.406 0.436 A (SEQ ID NO: 1274) CDH20 05 ttaaggcagaacaatc[A/G] tcatatctgttcagga 03 rs2850768 18 q q21.33 KDSR  61001410 6.16E− 0.90 0.190 0.208 G (SEQ ID NO: 1275) 03 tacattacagaatgaa[A/G] agaaaagagggcttgg 03 rs12969516 18 q q22.2 SOCS6|  68518485 6.27E− 0.92 0.445 0.466 G (SEQ ID NO: 1276) CBLN2 03 gcttgagctctctttt[A/G] aggattcatctttgac 03 rs7235677 18 q q22.2 SOCS6|  68552596 1.23E− 1.14 0.200 0.181 G (SEQ ID NO: 1277) CBLN2 03 agaggttgcaagcaca[A/G] gtatttgacacactgt 03 rs4555235 18 q q22.3 LOC  71071370 6.68E− 1.09 0.504 0.483 A (SEQ ID NO: 1278) 100289370| 03 tctctggctttaaaca[A/G] FBXO15 aaagatgactaaaact 02 exm1392554 18 q q22.3 TIMM21  71816278 3.44E− 3.66 0.026 0.007 A (SEQ ID NO: 1279) 17 aaaagcaaaggaggat[A/G] gcagcaaacaagtgtc 03 rs8084536 18 q q23 FLJ44313|  74227791 1.30E− 1.11 0.417 0.392 G (SEQ ID NO: 1280) LOC284276 03 cccaccagcagtatac[A/G] aggcttctcatttcac 03 rs4891030 18 q q23 LOC284276|  74295607 3.91E− 0.89 0.196 0.214 G (SEQ ID NO: 1281) FLJ44881 03 agagaaataagtggat[A/G] taacagagtggatctg 03 rs11874114 18 q q23 MBP  74699134 1.41E− 1.23 0.062 0.051 A (SEQ ID NO: 1282) 03 agtggactttggggcc[A/G] tcgtgccggatcctcc 03 rs8086634 18 q q23 MBP  74701192 2.52E− 1.23 0.087 0.072 A (SEQ ID NO: 1283) 04 cgctactcctagcccc[A/G] gaaagggctcacggtg 03 rs11669407 19 p p13.11 CHERP|  16654444 2.29E− 0.90 0.142 0.155 A (SEQ ID NO: 1284) SLC35E1 02 aggaggcaagatcaag[A/G] atttttttttttctaa 02 exm1442461 19 p p13.11 SLC27A1  17597661 2.51E− 7.24 0.017 0.002 A (SEQ ID NO: 1285) 20 agcagcgcggcctcca[A/T] gcccgccttggccagg 03 rs794084 19 p p13.2 XAB2   7692058 4.63E− 1.12 0.422 0.395 G (SEQ ID NO: 1286) 04 ctgggtgacatcctac[A/G] cggagctagtgtcaca 02 exm1400852 19 p p13.3 APC2   1468696 1.17E− Inf 0.003 0.000 A (SEQ ID NO: 1287) 07 ctgggcacggggtgcc[A/G] ggctggggacgtagat 02 rs313784 19 p p13.3 BRUNOL5   3293593 1.27E− 0.90 0.232 0.252 A (SEQ ID NO: 1288) 05 ggtggggtgatgcttc[A/G] agaggctacaagaaac 03 rs1610045 19 p p13.3 BTBD2   1997363 1.61E− 0.88 0.300 0.328 G (SEQ ID NO: 1289) 04 gcagtgcgaggaaggc[A/G] gcgggttccacgtcgg 03 rs12976454 19 p p13.3 C19orf28   3544971 5.02E− 1.13 0.312 0.288 A (SEQ ID NO: 1290) 04 cgggggggtggtaccc[A/G] cggtgcctactcatcc 03 rs3916080 19 p p13.3 FUT6   5832899 2.02E− 0.90 0.345 0.369 A (SEQ ID NO: 1291) 03 ccttttctggtgtgtc[A/C] ccagactcttcctcaa 03 rs11878982 19 p p13.3 KDM4B   5041049 1.37E− 1.15 0.252 0.227 A (SEQ ID NO: 1292) 04 cacccatgaaagaggc[A/G] ggaggggctctgctcc 02 rs33938520 19 p p13.3 KDM4B   4984588 4.40E− 1.15 0.292 0.264 A (SEQ ID NO: 1293) 05 acctgacgaggcgtac[A/G] gaacaggccggaacag 03 rs4805077 19 q q13.11 LSM14A|  34742705 2.08E− 1.08 0.381 0.363 G (SEQ ID NO: 1294) KIAA0355 02 ttccagtgtgaacatg[A/G] catcaaagaagaggca 03 rs6510478 19 q q13.12 CD22  35834621 2.20E− 0.87 0.234 0.260 G (SEQ ID NO: 1295) 04 cccacacctcatagca[A/G] gatctcatctctacaa 03 rs7251526 19 q q13.12 CD22  35829513 4.64E− 0.90 0.263 0.283 A (SEQ ID NO: 1296) 03 aaaacaagcatctacc[A/G] agcaccctccatgagc 02 rs4806152 19 q q13.12 FFAR3|  35886660 5.27E− 0.84 0.204 0.235 C (SEQ ID NO: 1297) LOC 06 caagtgagagcagata[A/C] 100128682 ggcagcacagggattc 03 rs11669734 19 q q13.12 MAG  35794775 1.41E− 0.89 0.233 0.254 A (SEQ ID NO: 1298) 03 cgatattccagaggga[A/G] ttgcttaaggaagggg 02 exm1458802 19 q q13.12 WDR62  36546015 8.28E− 5.91 0.017 0.003 A (SEQ ID NO: 1299) 18 tcggaggccgtcgaga[A/G] tcgcgtccgccgccgt 03 rs234341 19 q q13.2 PSMC4  40486136 1.29E− 1.25 0.034 0.027 A (SEQ ID NO: 1300) 02 ctaaggggtggttatc[A/G] tgacaggaaggaggta 03 rs17289513 19 q q13.32 AP2S1|  47412622 3.06E− 0.85 0.087 0.101 A (SEQ ID NO: 1301) GRLF1 03 cagtagactttcaagg[A/G] ctagtaactcgcatgc 02 exm1493646 19 q q13.33 MYH14  50747534 4.61E− 95.0 0.010 0.000 A (SEQ ID NO: 1302) 24 5 ttcaaggcaatgttgc[A/C] aaactggagaactgct 03 rs10403102 19 q q13.33 TPRX1|CRX  48317892 4.87E− 0.91 0.452 0.474 A (SEQ ID NO: 1303) 03 aggtgtctgatcaacg[A/C] cctcagagatgacctg 03 rs11881877 19 q q13.41 ZNF320|  53401760 1.11E− 0.89 0.446 0.476 A (SEQ ID NO: 1304) LOC388559 04 gatttttaaaaaaagc[A/G] ttgacattgtaacagt 03 rs6080719 20 p p12.1 BFSP1  17477592 5.89E− 1.11 0.254 0.236 A (SEQ ID NO: 1305) 03 tctcagcactggatcc[A/G] gtgggaaaggtaacgc 03 rs1333400 20 p p12.1 BTBD3|  12693139 6.20E− 1.11 0.522 0.495 G (SEQ ID NO: 1306) LOC 04 catgcccagagtatgg[A/G] 100289040 tatattgggggaatca 02 rs1333383 20 p p12.1 BTBD3|  12710164 5.83E− 0.88 0.384 0.415 A (SEQ ID NO: 1307) LOC 05 attgaactgtaactta[A/C] 100289040 acagagcaaacattgt 03 rs4814155 20 p p12.1 BTBD3|  12708838 1.08E− 0.88 0.374 0.403 G (SEQ ID NO: 1308) LOC 04 gcctactaacagcaag[A/G] 100289040 gcctttattaatattt 02 rs6111020 20 p p12.1 KIF16B  16273832 7.40E− 1.14 0.364 0.334 A (SEQ ID NO: 1309) 05 acccatgggttctatc[A/G] atttctgccatatcct 03 rs7263619 20 p p12.1 KIF16B  16447367 1.08E− 0.91 0.204 0.220 A (SEQ ID NO: 1310) 02 gtgtccacctgtatta[A/G] agtgttttcatgtgct 03 rs7273594 20 p p12.1 KIF16B  16302535 3.12E− 1.14 0.143 0.128 A (SEQ ID NO: 1311) 03 cacagttttcccataa[A/G] agctcaaatatctttg 03 rs6111005 20 p p12.1 KIF16B  16256912 1.64E− 0.86 0.113 0.129 G (SEQ ID NO: 1312) 03 gcctaaagggtataat[A/G] agaagagaagtaaaag 03 rs6043962 20 p p12.1 KIF16B  16438733 6.11E− 1.13 0.286 0.262 C (SEQ ID NO: 1313) 04 ggctcacagcaaaact[A/C] taccgttttgatctgg 03 rs8120353 20 p p12.1 KIF16B  16412764 1.15E− 0.90 0.158 0.173 A (SEQ ID NO: 1314) 02 gtcagatgggcctgat[A/G] tcaagataaggcctac 03 rs1028539 20 p p12.1 KIF16B  16445463 3.42E− 1.14 0.244 0.221 A (SEQ ID NO: 1315) 04 tacttgcatcccaacc[A/G] cctaaaagtgttggtt 03 rs8116503 20 p p12.1 KIF16B  16359650 8.91E− 0.90 0.184 0.201 A (SEQ ID NO: 1316) 03 tggagtccagagagaa[A/G] cagcagagagaggcgc 03 rs6085463 20 p p12.3 FERMT1|   6252538 1.46E− 0.92 0.388 0.407 A (SEQ ID NO: 1317) BMP2 02 cttcaacctcatgtta[A/G] atcagtacttataagc 02 exm1519568 20 p p13 TGM3   2297721 4.47E− Inf 0.004 0.000 A (SEQ ID NO: 1318) 11 tctgcccagatcaata[A/G] caatgatgacaatggt 03 rs4911107 20 q q11.21 DNMT3B  31374991 3.21E− 0.91 0.378 0.401 A (SEQ ID NO: 1319) 03 ttggtctctggtcacc[A/G] acatcctttgctctgg 02 exm1534977 20 q q11.22 E1F252  32685262 1.32E− Inf 0.023 0.000 A (SEQ ID NO: 1320) 35 tgagcctgcccaagca[A/G] ggcctgtctgattact 03 rs8050 20 q q11.22 RBM12  34237224 3.52E− 0.73 0.021 0.028 A (SEQ ID NO: 1321) 03 ccatacctgtacacaa[A/C] cacagactccagtaaa 02 rs16988087 20 q q12 LOC339568|  38087936 3.89E− 1.21 0.136 0.115 A (SEQ ID NO: 1322) MAFB 05 ctaaatcaaatgacaa[A/G] gagaaaagttagcttt 03 rs7263998 20 q q12 LOC339568|  38022796 1.65E− 1.19 0.135 0.116 A (SEQ ID NO: 1323) MAFB 04 tctcttccccccacaa[A/G] gtcattttcttaattc 03 rs6028507 20 q q12 LOC339568|  38181661 9.17E− 1.14 0.187 0.168 G (SEQ ID NO: 1324) MAFB 04 ccaagaaaaagtgccc[A/G] caagaaaaccaaaaca 03 rs11697337 20 q q12 LOC339568|  38236027 1.06E− 1.25 0.035 0.028 A (SEQ ID NO: 1325) MAFB 02 cacagttactcaagtc[A/G] agaggcaaaaaaaaaa 03 rs6101558 20 q q12 LOC339568|  38090963 8.72E− 1.16 0.174 0.154 G (SEQ ID NO: 1326) MAFB 05 tgtgactaaaccactc[A/G] tctgtttcccccactc 02 rs13044948 20 q q12 LOC339568|  38062804 1.20E− 1.23 0.132 0.110 A (SEQ ID NO: 1327) MAFB 05 attaaatatatttttc[A/G] taataacccagctaga 03 rs2207799 20 q q12 LOC339568|  38195894 1.99E− 1.26 0.069 0.055 A (SEQ ID NO: 1328) MAFB 04 tattaacattcataaa[A/C] cattcagacaattgct 02 rs13036738 20 q q12 LOC339568|  38078988 1.64E− 1.22 0.132 0.110 C (SEQ ID NO: 1329) MAFB 05 tgcctatttctaaact[A/C] tgctggggaaagcagg 02 rs13044925 20 q q12 LOC339568|  38085378 1.81E− 1.22 0.133 0.111 G (SEQ ID NO: 1330) MAFB 05 aggagattagggtgtt[A/G] attttcccgttctttc 03 rs2143216 20 q q12 LOC339568|  38066525 1.62E− 1.17 0.183 0.161 A (SEQ ID NO: 1331) MAFB 04 ataaacttgccttact[A/G] tatacacacacatgca 03 rs8119002 20 q q12 PTPRT  41072290 1.06E− 0.89 0.145 0.160 A (SEQ ID NO: 1332) 02 ccagggctatgaaacc[A/G] tctcattctgcagcag 03 rs6090639 20 q q13.12 EYA2|  45835008 2.30E− 1.16 0.180 0.159 G (SEQ ID NO: 1333) ZMYND8 04 ttttagggggtgtgat[A/G] tctgctatgtggacac 02 exm2264714 20 q q13.13 B4GALT5|  48383467 3.26E− Inf 0.005 0.000 C (SEQ ID NO: 1334) SLC9A8 10 ggattacaggcatgag[A/C] caccacatgctgccat 03 rs13041253 20 q q13.13 LOC  46773023 3.39E− 1.14 0.227 0.205 G (SEQ ID NO: 1335) 100130589 04 atgagttggaagaggt[A/G] LOC28474|9 ttagagtccccatcgt 03 rs162076 20 q q13.13 LOC  46785499 1.17E− 1.13 0.461 0.431 G (SEQ ID NO: 1336) 100130589| 04 ggttttcaggaatgca[A/G] LOC284749 aagtctgagaagacac 03 rs927478 20 q q13.13 LOC  46761590 2.66E− 1.15 0.227 0.203 A (SEQ ID NO: 1337) 100130589| 04 taagacaaagataagg[A/G] LOC284749 tctaatttcattcttt 03 rs852353 20 q q13.13 LOC  46833654 2.34E− 1.12 0.453 0.425 A (SEQ ID NO: 1338) 100130589| 04 aatttttccttagaag[A/C] LOC284749 ctcaacctcagcatac 03 rs852373 20 q q13.13 LOC  46841297 4.67E− 0.90 0.212 0.231 G (SEQ ID NO: 1339) 100130589| 03 ggggtcccttccctgc[A/G] LOC284749 ctctcataagctcccc 02 rs162079 20 q q13.13 LOC  46784745 8.36E− 1.16 0.239 0.214 A (SEQ ID NO: 1340) 100130589| 05 tcgagggctagagagt[A/G] LOC284749 atgagagtgggtgggg 03 rs6023407 20 q q13.2 DOK5  53221238 9.11E− 0.93 0.329 0.346 G (SEQ ID NO: 1341) 05 atgtatatttaaggta[A/G] gcttttctttttccct 03 rs6064102 20 q q13.2 DOK5|CBLN4  53283735 7.76E− 0.88 0.123 0.137 A (SEQ ID NO: 1342) 03 tgacatccctcctatc[A/G] ggtctttgagggagaa 02 exm1550638 20 q q13.2 SALL4  50408481 1.26E− Inf 0.003 0.000 A (SEQ ID NO: 1343) 07 agtggccaacactaat[A/G] tgaccttgcaggcact 02 rs6013748 20 q q13.2 ZNF217|  52275163 1.44E− 1.17 0.177 0.156 A (SEQ ID NO: 1344) SUMO1P1 05 agcatatttggcctcc[A/G] taatgccgcttaaggt 03 rs6025739 20 q q13.31 PMEPA1|  56294313 1.40E− 1.18 0.100 0.086 G (SEQ ID NO: 1345) LOC 03 taaatggcaattgttc[A/G] 100129869 tgcaataaagaacaat 03 rs170602 20 q q13.31 RBM38|  56019162 2.24E− 0.89 0.222 0.242 G (SEQ ID NO: 1346) HMGB1L1 03 ctcatctcttctagcc[A/G] gctttccccttacagg 03 rs6129089 20 q q13.33 CDH4  59850852 2.39E− 1.11 0.270 0.249 A (SEQ ID NO: 1347) 03 ttccacccccagtgat[A/G] ctcagaatccaggatc 03 rs2427021 20 q q13.33 CDH4  59845250 1.52E− 1.15 0.157 0.140 A (SEQ ID NO: 1348) 03 ataaataacgatagcc[A/G] gtaacttacgttcact 03 rs6010784 20 q q13.33 DIDO1  61540319 1.25E− 0.90 0.474 0.500 A (SEQ ID NO: 1349) 03 ctcatgctgcgctgct[A/G] tcagaggccacatctg 01 JBL0001 20 q q13.33 LAMA5  60892450 5.28E− 3.95 0.020 0.010 T (SEQ ID NO: 1350) 12 9 tgtgcgtgggcctcgg[C/T] ggcctccactagacgc 03 rs6015653 20 q q13.33 LOC729296|  58692731 4.54E− 1.21 0.095 0.080 A (SEQ ID NO: 1351) CDH4 04 actgggttttgtggac[A/C] ctttgcagaggtcggg 03 rs2426990 20 q q13.33 LOC729296|  59788003 9.56E− 1.09 0.356 0.337 G (SEQ ID NO: 1352) CDH4 03 gtgccttttaatatat[A/G] gaccacaagctcagag 03 rs2426983 20 q q13.33 LOC729296|  59777873 1.43E− 1.08 0.424 0.405 C (SEQ ID NO: 1353) CDH4 02 cattgacacactggca[A/C] actcaatactgtgcac 03 rs6028076 20 q q13.33 LOC729296|  59801421 2.54E− 1.08 0.359 0.343 G (SEQ ID NO: 1354) CDH4 02 cccaaaaggaaaccct[A/G] aacccaataagcagtc 03 rs2426986 20 q q13.33 LOC729296|  59786367 1.33E− 1.11 0.167 0.153 G (SEQ ID NO: 1355) CDH4 02 tgttactgaggtatgc[A/G] atgccatgatttccac 03 rs6028080 20 q q13.33 LOC729296|  59804478 8.27E− 1.15 0.168 0.149 G (SEQ ID NO: 1356) CDH4 04 tgtaaatcaccacctc[A/G] ttttgttcctagagct 03 rs2427000 20 q q13.33 LOC729296|  59802749 2.07E− 1.09 0.269 0.254 A (SEQ ID NO: 1357) CDH4 02 cccttgccataaattg[A/G] aatccagagctgtaag 03 rs2426993 20 q q13.33 LOC729296|  59798418 1.03E− 1.12 0.167 0.153 G (SEQ ID NO: 1358) CDH4 02 acttctactcagcata[A/G] aatgggccgttgccaa 03 rs6027379 20 q q13.33 LOC729296|  58747589 9.67E− 0.89 0.445 0.474 G (SEQ ID NO: 1359) CDH4 05 ccataaaaggccggct[A/G] tagactcacatgtttt 02 rs1023361 21 q q21.1 NCAM2|  23344282 3.08E− 1.13 0.049 0.044 A (SEQ ID NO: 1360) NCRNA00158 05 gtttaaatgaaataaa[A/G] catcctctgtttgcgg 03 rs390955 21 q q21.3 ADAMTS1|  28218457 8.60E− 0.89 0.283 0.307 C (SEQ ID NO: 1361) ADAMTS5 04 cgcacgccacctcttc[A/C] ccagagacgactttgt 03 rs10482984 21 q q21.3 LOC  28820729 7.34E− 1.22 0.075 0.062 G (SEQ ID NO: 1362) 100288252| 04 tggaagaagaggtaag[A/G] NCRNA00113 tatctccagagccgct 03 rs12482697 21 q q22.11 ATP5O|  35293199 2.60E− 0.81 0.081 0.098 C (SEQ ID NO: 1363) FLJ46020 04 gtttctccctttgccc[A/C] caccactaaaatacag 03 rs11701963 21 q q22.11 ATP5O|  35323657 1.08E− 0.80 0.055 0.068 A (SEQ ID NO: 1364) FLJ46020 03 agtccaagcagcacct[A/G] gtaattaaactgagtc 03 rs2032314 21 q q22.11 FLJ46020|  35354523 2.40E− 0.82 0.063 0.075 A (SEQ ID NO: 1365) MRPS6 03 gcaaatctatacagac[A/G] gacacagattcatggt 03 rs2070371 21 q q22.11 HUNK  33368188 6.19E− 1.13 0.246 0.223 A (SEQ ID NO: 1366) 04 tctgaatctgtgtcat[A/G] agcgagcctgagggct 03 rs198914 21 q q22.11 KRTAP6-2|  31973405 7.04E− 0.89 0.275 0.299 A (SEQ ID NO: 1367) KRTAP22-1 04 ctcagttgtatagcag[A/G] atcagattctagagtt 03 rs2834889 21 q q22.12 RUNX1|  36675294 4.79E− 0.90 0.437 0.464 C (SEQ ID NO: 1368) SETD4 04 agaaaccagccatttg[A/C] atgcgctcaatggaat 03 rs6517494 21 q q22.2 FLJ45139|  40330767 6.46E− 1.10 0.314 0.295 A (SEQ ID NO: 1369) LOC 03 aaaaagctacgcccac[A/C] 100289305 tcctaaccctcggact 02 exm1571045 21 q q22.2 LCA5L  40778182 2.87E− 1.47 0.127 0.090 A (SEQ ID NO: 1370) 10 ggggccagccaatgcc[A/G] gcaacatgaggtacag 02 rs9981939 21 q q22.3 C21orf121|  43473602 2.00E− 1.13 0.259 0.236 C (SEQ ID NO: 1371) UMODL1 05 tataaccttccaaaaa[A/C] ttcaacatcatcttcc 02 rs467997 21 q q22.3 C21orf121|  43488016 3.66E− 1.16 0.279 0.251 A (SEQ ID NO: 1372) UMODL1 05 aaaggaaaagtcattc[A/G] ggctgtgataagaaag 02 rs2839452 21 q q22.3 C21orf121|  43466047 1.88E− 1.13 0.289 0.265 G (SEQ ID NO: 1373) UMODL1 05 taccactaattccaat[A/G] ctcaagaagagctgac 03 rs220263 21 q q22.3 C21orf121|  43482161 5.74E− 1.13 0.471 0.440 G (SEQ ID NO: 1374) UMODL1 05 ccccacgtgaactcgc[A/G] gcaggcagagaatcta 03 rs762395 21 q q22.3 C21orf136|  44769676 5.57E− 1.10 0.361 0.340 A (SEQ ID NO: 1375) FLJ41733 03 gggctcgtttcagaat[A/G] cggttgggcaagtttg 03 rs9978582 21 q q22.3 COL6A1|  47488387 2.34E− 0.91 0.417 0.441 C (SEQ ID NO: 1376) COL6A2 03 tccgtctacagccacc[A/C] agttaaataacagcgg 03 rs2282527 21 q q22.3 RRP1B  45081426 3.72E− 1.10 0.357 0.336 A (SEQ ID NO: 1377) 03 gttcacctcctgatga[A/C] ataaattcttgaccgt 03 rs3814903 21 q q22.3 TMPRSS3|  43817117 3.43E− 1.12 0.363 0.336 A (SEQ ID NO: 1378) UBASH3A 04 gggctatttgataggc[A/C] cacggcagcttgggtt 03 rs5992034 22 q q11.1 CECR1|  17852805 1.63E− 1.15 0.144 0.128 A (SEQ ID NO: 1379) CECR2 03 aatccatgagttcagc[A/C] tggtgagatctttccc 03 rs1296795 22 q q11.21 CECR2  18021760 1.19E− 0.87 0.235 0.262 G (SEQ ID NO: 1380) 04 cattgcgtcctttccc[A/G] aagagtctgttcccat 03 rs714027 22 q q12.2 HORMAD2|  30577771 4.03E− 1.09 0.475 0.453 A (SEQ ID NO: 1381) 03 aaagaattttccccca[A/G] tgctctagcaaattgc 03 rs1049536 22 q q12.2 THOC5LIF  29904354 5.88E− 1.11 0.245 0.227 A (SEQ ID NO: 1382) 03 ggctggtgtctttgga[A/G] aatatcaagagtcaca 03 rs2016485 22 q q12.3 LARGE  34086416 7.28E− 0.92 0.442 0.463 A (SEQ ID NO: 1383) 03 gtcattcagccctccc[A/G] gcaaccccagaaatag 03 rs739166 22 q q13.1 ELFN2|  37863459 9.09E− 1.12 0.267 0.244 G (SEQ ID NO: 1384) MFNG 05 gaagtgacccatctgg[A/G] ccccagaggcaggggc 02 rs1005522 22 q q13.1 MAP3K7IP1|  39845898 7.35E− 1.15 0.271 0.244 C (SEQ ID NO: 1385) MGAT3 05 cctgcagcacccctgg[A/C] cctcatggggcacttc 02 exm1609618 22 q q13.1 PDGFB  39621819 2.38E− 4.42 0.009 0.002 A (SEQ ID NO: 1386) 08 ccggcggactcgcacc[A/G] tccgaatggtcacccg 03 rs2187793 22 q q13.31 LOC  47688003 2.72E− 0.89 0.330 0.357 A (SEQ ID NO: 1387) 100289420| 04 tgcaaaatgcttctga[A/G] FAM19A5 atgggtcaaccagaag 03 rs16993202 22 q q13.31 PHF21B  45353413 1.02E− 0.84 0.097 0.113 G (SEQ ID NO: 1388) 03 aaagagagggctgact[A/G] ttgattctgtgcatac 03 rs736490 22 q q13.31 PHF21B  45338213 4.34E− 0.82 0.078 0.094 A (SEQ ID NO: 1389) 04 agagggtgcccccagg[A/G] tcctactgtggatcag 03 rs138850 22 q q13.33 BRD1  50193337 1.71E− 1.12 0.241 0.220 G (SEQ ID NO: 1390) 03 gaagggagcaggtgct[A/G] tcaatggaaatgggac 03 rs138843 22 q q13.33 BRD1  50183162 3.97E− 1.14 0.251 0.228 A (SEQ ID NO: 1391) 04 gaatgtcgtaatcagg[A/G] cgagagctcggggcgg 03 rs5769373 22 q q13.33 LOC  49411595 7.63E− 1.06 0.413 0.399 A (SEQ ID NO: 1392) 100128946| 02 caagtctctcagtgac[A/G] LOC gggccgacacttggtc 100287247 03 rs5769807 22 q q13.33 LOC  49415539 1.58E− 1.09 0.303 0.285 G (SEQ ID NO: 1393) 100128946| 02 aactttctgtaaagca[A/G] LOC tgggagttagggcaac 100287247 03 rs2064542 22 q q13.33 LOC  49430916 5.02E− 1.07 0.399 0.384 C (SEQ ID NO: 1394) 100128946| 02 ctgcctctaaacccga[A/C] LOC gtcttcaagcctgact 100287247 03 rs1548245 22 q q13.33 LOC  49412197 5.13E− 1.07 0.249 0.236 A (SEQ ID NO: 1395) 100128946| 02 gtgtcgtggcagatac[A/C] LOC aggtctcacggaagtc 100287247 03 rs4823969 22 q q13.33 LOC  49416063 6.92E− 1.11 0.207 0.190 G (SEQ ID NO: 1396) 100128946| 03 gtgagctgcacatcct[A/G] LOC cctagaagggacatct 100287247 03 rs5770992 22 q q13.33 SHANK3  51146139 1.21E− 0.81 0.092 0.111 G (SEQ ID NO: 1397) 04 tagctattccaaataa[A/G] ataaaacccaaagaaa 02 rs1007461 X p p22.2 CLCN4|MID1  10297210 1.36E− 1.19 0.466 0.423 A (SEQ ID NO: 1398) 04 ccaatgtatgtgaagt[G/A] gctcaaatgaattttg 

1. A method of treating pain comprising applying at least one therapeutic to a patient having at least one gynecological disorder associated biomarker.
 2. The method of claim 1, wherein said therapeutic defines at least one of the administration or cancellation of a compound and the administration or cancellation of an invasive procedure.
 3. The method of claim 2, wherein said compound defines an estrogen containing composition, a progesterone containing composition, a progestin containing composition, and a gonadotropin releasing-hormone (GnRH) agonist, and wherein said invasive procedure defines a laparoscopy.
 4. The method of claim 1, wherein said gynecological disorder defines dysmenorrhea.
 5. The method of claim 1, wherein said gynecological disorder associated biomarker defines at least one of an increased risk of a disorder biomarker and a decreased risk of a disorder biomarker.
 6. The method of claim 1, wherein said at least one gynecological disorder associated biomarker is located in the DNA of said patient.
 7. The method of claim 1, wherein said at least one gynecological disorder associated biomarker defines the minor allele of at least one biomarker of table
 1. 8. A method of treating infertility comprising applying at least one therapeutic to a patient having at least one gynecological disorder associated biomarker.
 9. The method of claim 8, wherein said therapeutic defines at least one of the administration or cancellation of a compound and the administration or cancellation of an invasive procedure.
 10. The method of claim 9, wherein said compound defines an estrogen containing composition, a progesterone containing composition, a progestin containing composition, and a gonadotropin releasing-hormone (GnRH) agonist, and wherein said invasive procedure defines at least one of a laparoscopy and an Advanced Reproductive Therapy.
 11. The method of claim 8, wherein said gynecological disorder defines endometriosis.
 12. The method of claim 8, wherein said gynecological disorder associated biomarker defines at least one of an increased risk of a disorder biomarker and a decreased risk of a disorder biomarker.
 13. The method of claim 8, wherein said at least one gynecological disorder associated biomarker is located in the DNA of said patient.
 14. The method of claim 8, wherein said at least one gynecological disorder associated biomarker defines the minor allele of at least one biomarker of table
 1. 15. A method of treating at least one of pain and infertility comprising applying at least one therapeutic to a patient having at least one gynecological disorder associated biomarker.
 16. The method of claim 15, wherein said therapeutic defines at least one of the administration or cancellation of a compound and the administration or cancellation of an invasive procedure.
 17. The method of claim 16, wherein said compound defines an estrogen containing composition, a progesterone containing composition, a progestin containing composition, and a gonadotropin releasing-hormone (GnRH) agonist, and wherein said invasive procedure defines at least one of a laparoscopy and an Advanced Reproductive Therapy.
 18. The method of claim 15, wherein said gynecological disorder defines at least one of dysmenorrhea and endometriosis.
 19. The method of claim 15, wherein said gynecological disorder associated biomarker defines at least one of an increased risk of a disorder biomarker and a decreased risk of a disorder biomarker.
 20. The method of claim 15, wherein said at least one gynecological disorder associated biomarker is located in the DNA of said patient.
 21. The method of claim 15, wherein said at least one gynecological disorder associated biomarker defines the minor allele of at least one biomarker of table
 1. 